| Clinical significance of symptoms in smokers with preserved pulmonary function PG Woodruff, RG Barr, E Bleecker, SA Christenson, D Couper, JL Curtis, ... New England Journal of Medicine 374 (19), 1811-1821, 2016 | 739 | 2016 |
| Clinical and radiologic disease in smokers with normal spirometry EA Regan, DA Lynch, D Curran-Everett, JL Curtis, JHM Austin, ... JAMA internal medicine 175 (9), 1539-1549, 2015 | 461 | 2015 |
| Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis MH Cho, MLN McDonald, X Zhou, M Mattheisen, PJ Castaldi, CP Hersh, ... The lancet Respiratory medicine 2 (3), 214-225, 2014 | 385 | 2014 |
| Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort MLK Han, PM Quibrera, EE Carretta, RG Barr, ER Bleecker, RP Bowler, ... The Lancet Respiratory Medicine 5 (8), 619-626, 2017 | 299 | 2017 |
| Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort AT Hastie, FJ Martinez, JL Curtis, CM Doerschuk, NN Hansel, ... The Lancet Respiratory Medicine 5 (12), 956-967, 2017 | 281 | 2017 |
| Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene ES Wan, PJ Castaldi, MH Cho, JE Hokanson, EA Regan, BJ Make, ... Respiratory research 15, 1-13, 2014 | 277 | 2014 |
| Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease JH Yun, A Lamb, R Chase, D Singh, MM Parker, A Saferali, J Vestbo, ... Journal of allergy and clinical immunology 141 (6), 2037-2047. e10, 2018 | 228 | 2018 |
| COPDGene® 2019: redefining the diagnosis of chronic obstructive pulmonary disease KE Lowe, EA Regan, A Anzueto, E Austin, JHM Austin, TH Beaty, ... Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation 6 (5 …, 2019 | 219 | 2019 |
| Cortisol levels and mortality in severe sepsis S Sam, TC Corbridge, B Mokhlesi, AP Comellas, ME Molitch Clinical endocrinology 60 (1), 29-35, 2004 | 211 | 2004 |
| Serious asthma events with fluticasone plus salmeterol versus fluticasone alone DA Stempel, IH Raphiou, KM Kral, AM Yeakey, AH Emmett, CM Prazma, ... New England Journal of Medicine 374 (19), 1822-1830, 2016 | 185 | 2016 |
| Cystic fibrosis carriers are at increased risk for a wide range of cystic fibrosis-related conditions AC Miller, AP Comellas, DB Hornick, DA Stoltz, JE Cavanaugh, AK Gerke, ... Proceedings of the National Academy of Sciences 117 (3), 1621-1627, 2020 | 162 | 2020 |
| Reduced bone density and vertebral fractures in smokers. Men and COPD patients at increased risk JD Jaramillo, C Wilson, DJ Stinson, DA Lynch, RP Bowler, S Lutz, JM Bon, ... Annals of the American Thoracic Society 12 (5), 648-656, 2015 | 157 | 2015 |
| A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry SM Lutz, MH Cho, K Young, CP Hersh, PJ Castaldi, ML McDonald, ... BMC genetics 16, 1-11, 2015 | 155 | 2015 |
| Iron oxide nanoparticles induce Pseudomonas aeruginosa growth, induce biofilm formation, and inhibit antimicrobial peptide function J Borcherding, J Baltrusaitis, H Chen, L Stebounova, CM Wu, ... Environmental Science: Nano 1 (2), 123-132, 2014 | 146 | 2014 |
| Ventilator-associated lung injury decreases lung ability to clear edema in rats E Lecuona, F Saldias, A Comellas, K Ridge, C Guerrero, JI Sznajder American journal of respiratory and critical care medicine 159 (2), 603-609, 1999 | 142 | 1999 |
| Hypoxia-mediated degradation of Na, K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system AP Comellas, LA Dada, E Lecuona, LM Pesce, NS Chandel, N Quesada, ... Circulation research 98 (10), 1314-1322, 2006 | 140 | 2006 |
| Comparison of proteomic assessment methods in multiple cohort studies LM Raffield, H Dang, KA Pratte, S Jacobson, LA Gillenwater, E Ampleford, ... Proteomics 20 (12), 1900278, 2020 | 133 | 2020 |
| The value of blood cytokines and chemokines in assessing COPD E Bradford, S Jacobson, J Varasteh, AP Comellas, P Woodruff, W O’Neal, ... Respiratory research 18, 1-11, 2017 | 124 | 2017 |
| β-Adrenergic stimulation restores rat lung ability to clear edema in ventilator-associated lung injury FJ Saldias, E Lecuona, AP Comellas, KM Ridge, DH Rutschman, ... American journal of respiratory and critical care medicine 162 (1), 282-287, 2000 | 118 | 2000 |
| Comparison between an alternative and the classic definition of chronic bronchitis in COPDGene V Kim, J Crapo, H Zhao, PW Jones, EK Silverman, A Comellas, BJ Make, ... Annals of the American Thoracic Society 12 (3), 332-339, 2015 | 113 | 2015 |
Eric A. HoffmanProfessor of Radiology, University of IowaEmail verificata su uiowa.edu