Articoli con mandati relativi all'accesso pubblico - Emma T van der WesthuizenUlteriori informazioni
Non disponibili pubblicamente: 3
Synthesis and Pharmacological Evaluation of Heterocyclic Carboxamides: Positive Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor with Weak …
JCC Dallagnol, E Khajehali, ET Van Der Westhuizen, M Jörg, C Valant, ...
Journal of Medicinal Chemistry 61 (7), 2875-2894, 2018
Mandati: Australian Research Council, National Health and Medical Research Council …
Biased Profile of Xanomeline at the Recombinant Human M4 Muscarinic Acetylcholine Receptor
JK McDonald, ET Van Der Westhuizen, V Pham, G Thompson, CC Felder, ...
ACS Chemical Neuroscience 13 (8), 1206-1218, 2022
Mandati: Australian Research Council, National Health and Medical Research Council …
Single nucleotide variations encoding missense mutations in G protein‐coupled receptors may contribute to autism
ET van der Westhuizen
British Journal of Pharmacology 181 (14), 2158-2181, 2024
Mandati: Wellcome Trust
Disponibili pubblicamente: 17
Relaxin family peptides and their receptors
RAD Bathgate, ML Halls, ET van der Westhuizen, GE Callander, M Kocan, ...
Physiological reviews 93 (1), 405-480, 2013
Mandati: National Health and Medical Research Council, Australia
Quantification of ligand bias for clinically relevant β2-adrenergic receptor ligands: implications for drug taxonomy
ET van der Westhuizen, B Breton, A Christopoulos, M Bouvier
Molecular pharmacology 85 (3), 492-509, 2014
Mandati: National Health and Medical Research Council, Australia, Canadian Institutes …
Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist
M Masureel, Y Zou, LP Picard, E van der Westhuizen, JP Mahoney, ...
Nature chemical biology 14 (11), 1059-1066, 2018
Mandati: US National Institutes of Health, American Heart Association, Canadian …
Endogenous allosteric modulators of G protein–coupled receptors
ET van der Westhuizen, C Valant, PM Sexton, A Christopoulos
Journal of Pharmacology and Experimental Therapeutics 353 (2), 246-260, 2015
Mandati: National Health and Medical Research Council, Australia
Impedance Responses Reveal β2-Adrenergic Receptor Signaling Pluridimensionality and Allow Classification of Ligands with Distinct Signaling Profiles
W Stallaert, JF Dorn, E van der Westhuizen, M Audet, M Bouvier
PloS one 7 (1), e29420, 2012
Mandati: Swiss National Science Foundation, Canadian Institutes of Health Research …
Crystal structure of the M5 muscarinic acetylcholine receptor
Z Vuckovic, PR Gentry, AE Berizzi, K Hirata, S Varghese, G Thompson, ...
Proceedings of the National Academy of Sciences 116 (51), 26001-26007, 2019
Mandati: Australian Research Council, National Health and Medical Research Council …
Purinergic receptor transactivation by the β2-adrenergic receptor increases intracellular Ca2+ in nonexcitable cells
W Stallaert, ET Van Der Westhuizen, AM Schönegge, B Plouffe, M Hogue, ...
Molecular pharmacology 91 (5), 533-544, 2017
Mandati: National Health and Medical Research Council, Australia, Canadian Institutes …
Fine tuning muscarinic acetylcholine receptor signaling through allostery and bias
ET Van der Westhuizen, KHC Choy, C Valant, S McKenzie-Nickson, ...
Frontiers in pharmacology 11, 606656, 2021
Mandati: Australian Research Council, National Health and Medical Research Council …
Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response
B Benredjem, J Gallion, D Pelletier, P Dallaire, J Charbonneau, D Cawkill, ...
Nature communications 10 (1), 4075, 2019
Mandati: US National Institutes of Health, Canadian Institutes of Health Research …
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics
Z Vuckovic, J Wang, V Pham, JI Mobbs, MJ Belousoff, A Bhattarai, ...
Elife 12, e83477, 2023
Mandati: US National Science Foundation, US Department of Energy, US National …
Assessment of the molecular mechanisms of action of novel 4-Phenylpyridine-2-one and 6-Phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors
ET van der Westhuizen, A Spathis, E Khajehali, M Jörg, SN Mistry, ...
Molecular Pharmacology 94 (1), 770-783, 2018
Mandati: Australian Research Council, National Health and Medical Research Council …
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity
M Jorg, ET van der Westhuizen, E Khajehali, WAC Burger, JM White, ...
ACS Chemical Neuroscience 10 (3), 1099-1114, 2018
Mandati: Australian Research Council, National Health and Medical Research Council …
Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits
HTM Nguyen, ET van der Westhuizen, CJ Langmead, AB Tobin, ...
British Journal of Pharmacology 181 (14), 2114-2142, 2024
Mandati: National Health and Medical Research Council, Australia, Wellcome Trust
Identification of a Novel Allosteric Site at the M5 Muscarinic Acetylcholine Receptor
WAC Burger, PR Gentry, AE Berizzi, Z Vuckovic, ET Van Der Westhuizen, ...
ACS Chemical Neuroscience 12 (16), 3112-3123, 2021
Mandati: Australian Research Council, National Health and Medical Research Council …
Development of Novel 4‐Arylpyridin‐2‐one and 6‐Arylpyrimidin‐4‐one Positive Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor
M Jörg, E Khajehali, ET van der Westhuizen, KH C. Choy, ...
ChemMedChem 16 (1), 216-233, 2021
Mandati: Australian Research Council, National Health and Medical Research Council …
Restoring Agonist Function at a Chemogenetically Modified M1 Muscarinic Acetylcholine Receptor
E Khajehali, S Bradley, ET Van Der Westhuizen, C Molloy, C Valant, ...
ACS Chemical Neuroscience 11 (24), 4270-4279, 2020
Mandati: National Health and Medical Research Council, Australia, Wellcome Trust
Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl) pyridine positive allosteric modulators for the M4 mAChR
M Jörg, ET van der Westhuizen, Y Lu, KHC Choy, DM Shackleford, ...
European Journal of Medicinal Chemistry 258, 115588, 2023
Mandati: Australian Research Council, National Health and Medical Research Council …
Le informazioni sulla pubblicazione e sul finanziamento vengono stabilite automaticamente da un software