| LRP-1-mediated intracellular antibody delivery to the Central Nervous System X Tian, S Nyberg, PS Sharp, J Madsen, N Daneshpour, SP Armes, ... Scientific reports 5 (1), 11990, 2015 | 168 | 2015 |
| Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer H Foster, PS Sharp, T Athanasopoulos, C Trollet, IR Graham, K Foster, ... Molecular therapy 16 (11), 1825-1832, 2008 | 138 | 2008 |
| Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression PS Sharp, MT Akbar, S Bouri, A Senda, K Joshi, HJ Chen, DS Latchman, ... Neurobiology of disease 30 (1), 42-55, 2008 | 135 | 2008 |
| Optimised and Rapid Pre-clinical Screening in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS) RJ Mead, EJ Bennett, AJ Kennerley, P Sharp, C Sunyach, P Kasher, ... PloS one 6 (8), e23244, 2011 | 119 | 2011 |
| Chronic systemic therapy with low-dose morpholino oligomers ameliorates the pathology and normalizes locomotor behavior in mdx mice A Malerba, PS Sharp, IR Graham, V Arechavala-Gomeza, K Foster, ... Molecular Therapy 19 (2), 345-354, 2011 | 107 | 2011 |
| Physiological characterization of muscle strength with variable levels of dystrophin restoration in mdx mice following local antisense therapy PS Sharp, H Bye-a-Jee, DJ Wells Molecular Therapy 19 (1), 165-171, 2011 | 97 | 2011 |
| Metformin Treatment Has No Beneficial Effect in a Dose-Response Survival Study in the SOD1G93A Mouse Model of ALS and Is Harmful in Female Mice HM Kaneb, PS Sharp, N Rahmani-Kondori, DJ Wells PloS one 6 (9), e24189, 2011 | 94 | 2011 |
| The effect of peripheral nerve injury on disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis PS Sharp, JRT Dick, L Greensmith Neuroscience 130 (4), 897-910, 2005 | 84 | 2005 |
| Key aspects of neurovascular control mediated by specific populations of inhibitory cortical interneurons L Lee, L Boorman, E Glendenning, C Christmas, P Sharp, P Redgrave, ... Cerebral Cortex 30 (4), 2452-2464, 2020 | 73 | 2020 |
| Neuropathology and behavioural features of transgenic murine models of Alzheimer's disease KE Ameen‐Ali, SB Wharton, JE Simpson, PR Heath, P Sharp, J Berwick Neuropathology and Applied Neurobiology 43 (7), 553-570, 2017 | 68 | 2017 |
| Heat shock protein 27 rescues motor neurons following nerve injury and preserves muscle function P Sharp, M Krishnan, O Pullar, R Navarrete, D Wells, J de Belleroche Experimental neurology 198 (2), 511-518, 2006 | 64 | 2006 |
| Comparison of stimulus-evoked cerebral hemodynamics in the awake mouse and under a novel anesthetic regime PS Sharp, K Shaw, L Boorman, S Harris, AJ Kennerley, M Azzouz, ... Scientific reports 5 (1), 12621, 2015 | 61 | 2015 |
| Transgenic overexpression of LARGE induces α-dystroglycan hyperglycosylation in skeletal and cardiac muscle M Brockington, S Torelli, PS Sharp, K Liu, S Cirak, SC Brown, DJ Wells, ... PLoS One 5 (12), e14434, 2010 | 44 | 2010 |
| Site specific modification of adeno-associated virus enables both fluorescent imaging of viral particles and characterization of the capsid interactome JS Chandran, PS Sharp, E Karyka, JMC Aves-Cruzeiro, I Coldicott, ... Scientific reports 7 (1), 14766, 2017 | 41 | 2017 |
| The time course of recognition memory impairment and glial pathology in the hAPP-J20 mouse model of Alzheimer’s disease KE Ameen-Ali, JE Simpson, SB Wharton, PR Heath, PS Sharp, G Brezzo, ... Journal of Alzheimer’s disease 68 (2), 609-624, 2019 | 36 | 2019 |
| A novel automated rodent tracker (ART), demonstrated in a mouse model of amyotrophic lateral sclerosis BM Hewitt, MH Yap, EF Hodson-Tole, AJ Kennerley, PS Sharp, RA Grant Journal of neuroscience methods 300, 147-156, 2018 | 33 | 2018 |
| Assessment of neurovascular coupling and cortical spreading depression in mixed mouse models of atherosclerosis and Alzheimer’s disease O Shabir, B Pendry, L Lee, B Eyre, PS Sharp, MA Rebollar, D Drew, ... Elife 11, e68242, 2022 | 31 | 2022 |
| Abnormalities in whisking behaviour are associated with lesions in brain stem nuclei in a mouse model of amyotrophic lateral sclerosis RA Grant, PS Sharp, AJ Kennerley, J Berwick, A Grierson, T Ramesh, ... Behavioural brain research 259, 274-283, 2014 | 30 | 2014 |
| Deep tissue translocation of graphene oxide sheets in human glioblastoma 3D spheroids and an orthotopic xenograft model I de Lázaro, P Sharp, C Gurcan, A Ceylan, M Stylianou, T Kisby, Y Chen, ... Advanced Therapeutics 4 (1), 2000109, 2021 | 25 | 2021 |
| Neurovascular coupling preserved in a chronic mouse model of Alzheimer’s disease: Methodology is critical PS Sharp, KE Ameen-Ali, L Boorman, S Harris, S Wharton, C Howarth, ... Journal of Cerebral Blood Flow & Metabolism 40 (11), 2289-2303, 2020 | 25 | 2020 |
Jason BerwickSheffieldEmail verificata su sheffield.ac.uk