The implications of alternative splicing in the ENCODE protein complement ML Tress, PL Martelli, A Frankish, GA Reeves, JJ Wesselink, C Yeats, ... Proceedings of the National Academy of Sciences 104 (13), 5495-5500, 2007 | 251 | 2007 |
Insights into the binding of Phenyltiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptor X Biarnés, A Marchiori, A Giorgetti, C Lanzara, P Gasparini, P Carloni, ... PloS one 5 (8), e12394, 2010 | 134 | 2010 |
Hypomorphic mutations in POLR3A are a frequent cause of sporadic and recessive spastic ataxia M Minnerop, D Kurzwelly, H Wagner, AS Soehn, J Reichbauer, F Tao, ... Brain 140 (6), 1561-1578, 2017 | 108 | 2017 |
Evaluating the usefulness of protein structure models for molecular replacement A Giorgetti, D Raimondo, AE Miele, A Tramontano Bioinformatics 21 (suppl_2), ii72-ii76, 2005 | 92 | 2005 |
GOMoDo: a GPCRs online modeling and docking webserver M Sandal, TP Duy, M Cona, H Zung, P Carloni, F Musiani, A Giorgetti PloS one 8 (9), e74092, 2013 | 85 | 2013 |
Coarse-grained/molecular mechanics of the TAS2R38 bitter taste receptor: experimentally-validated detailed structural prediction of agonist binding A Marchiori, L Capece, A Giorgetti, P Gasparini, M Behrens, P Carloni, ... PloS one 8 (5), e64675, 2013 | 84 | 2013 |
Evidence for a transient additional ligand binding site in the TAS2R46 bitter taste receptor M Sandal, M Behrens, A Brockhoff, F Musiani, A Giorgetti, P Carloni, ... Journal of chemical theory and computation 11 (9), 4439-4449, 2015 | 79 | 2015 |
Mutation analysis of violaxanthin de-epoxidase identifies substrate-binding sites and residues involved in catalysis G Saga, A Giorgetti, C Fufezan, GM Giacometti, R Bassi, T Morosinotto Journal of Biological Chemistry 285 (31), 23763-23770, 2010 | 71 | 2010 |
Site‐directed enzymatic PEGylation of the human granulocyte colony‐stimulating factor C Maullu, D Raimondo, F Caboi, A Giorgetti, M Sergi, M Valentini, ... The FEBS journal 276 (22), 6741-6750, 2009 | 62 | 2009 |
A homology model of the pore region of HCN channels A Giorgetti, P Carloni, P Mistrik, V Torre Biophysical journal 89 (2), 932-944, 2005 | 62 | 2005 |
A comprehensive picture of the mutations associated with aromatic amino acid decarboxylase deficiency: from molecular mechanisms to therapy implications R Montioli, M Dindo, A Giorgetti, S Piccoli, B Cellini, CB Voltattorni Human Molecular Genetics 23 (20), 5429-5440, 2014 | 61 | 2014 |
Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules A Grison, S Zucchelli, A Urzì, I Zamparo, D Lazarevic, G Pascarella, ... BMC genomics 15, 1-16, 2014 | 58 | 2014 |
Identification of new BMP6 pro‐peptide mutations in patients with iron overload C Piubelli, A Castagna, G Marchi, M Rizzi, F Busti, S Badar, M Marchetti, ... American journal of hematology 92 (6), 562-568, 2017 | 56 | 2017 |
Hybrid molecular mechanics/coarse-grained simulations for structural prediction of G-protein coupled receptor/ligand complexes M Leguèbe, C Nguyen, L Capece, Z Hoang, A Giorgetti, P Carloni Public Library of Science 7 (10), e47332, 2012 | 55 | 2012 |
All muscarinic acetylcholine receptors (M1-M5) are expressed in murine brain microvascular endothelium BM Radu, AMM Osculati, E Suku, A Banciu, G Tsenov, F Merigo, ... Scientific reports 7 (1), 5083, 2017 | 53 | 2017 |
Molecular modeling of ion channels: structural predictions A Giorgetti, P Carloni Current opinion in chemical biology 7 (1), 150-156, 2003 | 52 | 2003 |
Computational design of molecularly imprinted polymer for direct detection of melamine in milk F Bates, M Busato, E Piletska, MJ Whitcombe, K Karim, A Guerreiro, ... Separation Science and Technology 52 (8), 1441-1453, 2017 | 51 | 2017 |
Nicotine blocks the hyperpolarization-activated current Ih and severely impairs the oscillatory behavior of oriens-lacunosum moleculare interneurons M Griguoli, A Maul, C Nguyen, A Giorgetti, P Carloni, E Cherubini Journal of Neuroscience 30 (32), 10773-10783, 2010 | 46 | 2010 |
Apparent Mineralocorticoid Excess by a Novel Mutation and Epigenetic Modulation by HSD11B2 Promoter Methylation F Pizzolo, S Friso, F Morandini, F Antoniazzi, C Zaltron, S Udali, A Gandini, ... The Journal of Clinical Endocrinology & Metabolism 100 (9), E1234-E1241, 2015 | 44 | 2015 |
Predicting ligand binding poses for low-resolution membrane protein models: Perspectives from multiscale simulations J Schneider, K Korshunova, F Musiani, M Alfonso-Prieto, A Giorgetti, ... Biochemical and biophysical research communications 498 (2), 366-374, 2018 | 39 | 2018 |