| The immune landscape of cancer V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ... Immunity 48 (4), 812-830. e14, 2018 | 4830 | 2018 |
| An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ... Cell 173 (2), 400-416. e11, 2018 | 2910 | 2018 |
| Genomic classification of cutaneous melanoma R Akbani, KC Akdemir, B áArman Aksoy, M Albert, A Ally, SB Amin, ... Cell 161 (7), 1681-1696, 2015 | 2822 | 2015 |
| Oncogenic signaling pathways in the cancer genome atlas F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ... Cell 173 (2), 321-337. e10, 2018 | 2727 | 2018 |
| Integrated genomic characterization of papillary thyroid carcinoma N Agrawal, R Akbani, BA Aksoy, A Ally, H Arachchi, SL Asa, JT Auman, ... Cell 159 (3), 676-690, 2014 | 2689 | 2014 |
| Comprehensive characterization of cancer driver genes and mutations MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ... Cell 173 (2), 371-385. e18, 2018 | 2339 | 2018 |
| Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ... Cell 173 (2), 291-304. e6, 2018 | 2188 | 2018 |
| Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs MG Kris, BE Johnson, LD Berry, DJ Kwiatkowski, AJ Iafrate, II Wistuba, ... Jama 311 (19), 1998-2006, 2014 | 1862 | 2014 |
| Machine learning identifies stemness features associated with oncogenic dedifferentiation TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ... Cell 173 (2), 338-354. e15, 2018 | 1770 | 2018 |
| A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer FR Khuri, J Nemunaitis, I Ganly, J Arseneau, IF Tannock, L Romel, ... Nature medicine 6 (8), 879-885, 2000 | 1435 | 2000 |
| Integrated genomic characterization of oesophageal carcinoma Cancer Genome Atlas Research Network Nature 541 (7636), 169, 2017 | 1373 | 2017 |
| The BATTLE trial: personalizing therapy for lung cancer ES Kim, RS Herbst, II Wistuba, JJ Lee, GR Blumenschein Jr, A Tsao, ... Cancer discovery 1 (1), 44-53, 2011 | 1050 | 2011 |
| Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas TA Knijnenburg, L Wang, MT Zimmermann, N Chambwe, GF Gao, ... Cell reports 23 (1), 239-254. e6, 2018 | 986 | 2018 |
| Genomic and functional approaches to understanding cancer aneuploidy AM Taylor, J Shih, G Ha, GF Gao, X Zhang, AC Berger, SE Schumacher, ... Cancer cell 33 (4), 676-689. e3, 2018 | 957 | 2018 |
| Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition SY Sun, LM Rosenberg, X Wang, Z Zhou, P Yue, H Fu, FR Khuri Cancer research 65 (16), 7052-7058, 2005 | 957 | 2005 |
| Spatial organization and molecular correlation of tumor-infiltrating lymphocytes using deep learning on pathology images J Saltz, R Gupta, L Hou, T Kurc, P Singh, V Nguyen, D Samaras, ... Cell reports 23 (1), 181-193. e7, 2018 | 913 | 2018 |
| Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer SG Swisher, JA Roth, J Nemunaitis, DD Lawrence, BL Kemp, ... Journal of the National Cancer Institute 91 (9), 763-771, 1999 | 908* | 1999 |
| The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ... Cell reports 23 (1), 313-326. e5, 2018 | 895 | 2018 |
| Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth T Hitosugi, S Kang, MG Vander Heiden, TW Chung, S Elf, K Lythgoe, ... Science signaling 2 (97), ra73-ra73, 2009 | 861 | 2009 |
| Comprehensive analysis of alternative splicing across tumors from 8,705 patients A Kahles, KV Lehmann, NC Toussaint, M Hüser, SG Stark, ... Cancer cell 34 (2), 211-224. e6, 2018 | 801 | 2018 |
