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Inflammation, stress, and diabetes KE Wellen, GS Hotamisligil The Journal of clinical investigation 115 (5), 1111-1119, 2005 | 5758 | 2005 |
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Inflammatory mechanisms in obesity MF Gregor, GS Hotamisligil Annual review of immunology 29 (1), 415-445, 2011 | 4517 | 2011 |
A central role for JNK in obesity and insulin resistance J Hirosumi, G Tuncman, L Chang, CZ Görgün, KT Uysal, K Maeda, ... Nature 420 (6913), 333-336, 2002 | 4217 | 2002 |
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α-and obesity-induced insulin resistance GS Hotamisligil, P Peraldi, A Budavari, R Ellis, MF White, BM Spiegelman Science 271 (5249), 665-670, 1996 | 3704 | 1996 |
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease GS Hotamisligil Cell 140 (6), 900-917, 2010 | 3197 | 2010 |
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes U Ozcan, E Yilmaz, L Ozcan, M Furuhashi, E Vaillancourt, RO Smith, ... Science 313 (5790), 1137-1140, 2006 | 2853 | 2006 |
Obesity-induced inflammatory changes in adipose tissue KE Wellen, GS Hotamisligil The Journal of clinical investigation 112 (12), 1785-1788, 2003 | 2499 | 2003 |
Plasma adiponectin levels and risk of myocardial infarction in men T Pischon, CJ Girman, GS Hotamisligil, N Rifai, FB Hu, EB Rimm Jama 291 (14), 1730-1737, 2004 | 2445 | 2004 |
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth KM Nieman, HA Kenny, CV Penicka, A Ladanyi, R Buell-Gutbrod, ... Nature medicine 17 (11), 1498-1503, 2011 | 2320 | 2011 |
Inflammation, metaflammation and immunometabolic disorders GS Hotamisligil Nature 542 (7640), 177-185, 2017 | 2026 | 2017 |
Tumor necrosis factor α: a key component of the obesity-diabetes link GS Hotamisligil, BM Spiegelman Diabetes 43 (11), 1271-1278, 1994 | 1999 | 1994 |
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets M Furuhashi, GS Hotamisligil Nature reviews Drug discovery 7 (6), 489-503, 2008 | 1917 | 2008 |
Tumor necrosis factor alpha inhibits signaling from the insulin receptor. GS Hotamisligil, DL Murray, LN Choy, BM Spiegelman Proceedings of the National Academy of Sciences 91 (11), 4854-4858, 1994 | 1677 | 1994 |
Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance L Yang, P Li, S Fu, ES Calay, GS Hotamisligil Cell metabolism 11 (6), 467-478, 2010 | 1402 | 2010 |
Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism H Cao, K Gerhold, JR Mayers, MM Wiest, SM Watkins, GS Hotamisligil Cell 134 (6), 933-944, 2008 | 1317 | 2008 |