| Two tarantula peptides inhibit activation of multiple sodium channels RE Middleton, VA Warren, RL Kraus, JC Hwang, CJ Liu, G Dai, ... Biochemistry 41 (50), 14734-14747, 2002 | 292 | 2002 |
| Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-β-lactamase JH Toney, GG Hammond, PMD Fitzgerald, N Sharma, JM Balkovec, ... Journal of Biological Chemistry 276 (34), 31913-31918, 2001 | 256 | 2001 |
| Omarigliptin (MK-3102): a novel long-acting DPP-4 inhibitor for once-weekly treatment of type 2 diabetes T Biftu, R Sinha-Roy, P Chen, X Qian, D Feng, JT Kuethe, G Scapin, ... Journal of Medicinal Chemistry 57 (8), 3205-3212, 2014 | 194 | 2014 |
| Ligand activation domain of human orphan growth hormone (GH) secretagogue receptor (GHS-R) conserved from Pufferfish to humans OC Palyha, SD Feighner, CP Tan, KK McKee, DL Hreniuk, YD Gao, ... Molecular Endocrinology 14 (1), 160-169, 2000 | 166 | 2000 |
| Potassium channels: from scorpion venoms to high-resolution structure ML Garcia, YD Gao, OB McManus, GJ Kaczorowski Toxicon 39 (6), 739-748, 2001 | 147 | 2001 |
| Resiniferatoxin binds to the capsaicin receptor (TRPV1) near the extracellular side of the S4 transmembrane domain MZ Chou, T Mtui, YD Gao, M Kohler, RE Middleton Biochemistry 43 (9), 2501-2511, 2004 | 144 | 2004 |
| Drug-like density: a method of quantifying the “bindability” of a protein target based on a very large set of pockets and drug-like ligands from the Protein Data Bank RP Sheridan, VN Maiorov, MK Holloway, WD Cornell, YD Gao Journal of chemical information and modeling 50 (11), 2029-2040, 2010 | 129 | 2010 |
| Mimicry of erythropoietin by a nonpeptide molecule SA Qureshi, RM Kim, Z Konteatis, DE Biazzo, H Motamedi, R Rodrigues, ... Proceedings of the National Academy of Sciences 96 (21), 12156-12161, 1999 | 129 | 1999 |
| Attenuating pregnane X receptor (PXR) activation: a molecular modelling approach YD Gao, SH Olson, JM Balkovec, Y Zhu, I Royo, J Yabut, R Evers, EY Tan, ... Xenobiotica 37 (2), 124-138, 2007 | 115 | 2007 |
| Fullerenes with four-membered rings YD Gao, WC Herndon Journal of the American Chemical Society 115 (18), 8459-8460, 1993 | 92 | 1993 |
| A comparative study of the binding properties, dipeptidyl peptidase‐4 (DPP‐4) inhibitory activity and glucose‐lowering efficacy of the DPP‐4 inhibitors alogliptin, linagliptin … JP Berger, R SinhaRoy, A Pocai, TM Kelly, G Scapin, YD Gao, KAD Pryor, ... Endocrinology, diabetes & metabolism 1 (1), e00002, 2018 | 91 | 2018 |
| Interaction of agitoxin2, charybdotoxin, and iberiotoxin with potassium channels: selectivity between voltage‐gated and Maxi‐K channels YD Gao, ML Garcia Proteins: Structure, Function, and Bioinformatics 52 (2), 146-154, 2003 | 89 | 2003 |
| Tubular graphic carbon structures YD Gao, WC Herndon Molecular Physics 77 (3), 585-599, 1992 | 70 | 1992 |
| Binding of correolide to the Kv1. 3 potassium channel: characterization of the binding domain by site-directed mutagenesis M Hanner, B Green, YD Gao, WA Schmalhofer, M Matyskiela, DJ Durand, ... Biochemistry 40 (39), 11687-11697, 2001 | 67 | 2001 |
| (3R)-4-[(3R)-3-Amino-4-(2, 4, 5-trifluorophenyl) butanoyl]-3-(2, 2, 2-trifluoroethyl)-1, 4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of … T Biftu, D Feng, X Qian, GB Liang, G Kieczykowski, G Eiermann, H He, ... Bioorganic & Medicinal Chemistry Letters 17 (1), 49-52, 2007 | 64 | 2007 |
| Mathematical and chemical analysis of Wiener's polarity number H Hosoya, Y Gao Topology in Chemistry, 38-57, 2002 | 53 | 2002 |
| How do the polycyclic aromatic hydrocarbons approach infinity? H Hosoya, H Kumazaki, K Chida, M Ohuchi, YD Gao Pure and applied chemistry 62 (3), 445-450, 1990 | 53 | 1990 |
| Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis J Liu, D Guiadeen, A Krikorian, X Gao, J Wang, SB Boga, AB Alhassan, ... ACS Medicinal Chemistry Letters 7 (2), 198-203, 2016 | 46 | 2016 |
| Functional mapping of the transient receptor potential vanilloid 1 intracellular binding site DM Johnson, EM Garrett, R Rutter, TP Bonnert, YD Gao, RE Middleton, ... Molecular pharmacology 70 (3), 1005-1012, 2006 | 44 | 2006 |
| Discovery of novel tricyclic heterocycles as potent and selective DPP-4 inhibitors for the treatment of type 2 diabetes WL Wu, J Hao, M Domalski, DA Burnett, D Pissarnitski, Z Zhao, ... ACS medicinal chemistry letters 7 (5), 498-501, 2016 | 43 | 2016 |