Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3 L Alexopoulou, AC Holt, R Medzhitov, RA Flavell Nature 413 (6857), 732-738, 2001 | 8331 | 2001 |
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells W Zheng, RA Flavell Cell 89 (4), 587-596, 1997 | 3256 | 1997 |
Transforming growth factor-β regulation of immune responses MO Li, YY Wan, S Sanjabi, AKL Robertson, RA Flavell Annu. Rev. Immunol. 24 (1), 99-146, 2006 | 2966 | 2006 |
Help for cytotoxic-T-cell responses is mediated by CD40 signalling SRM Bennett, FR Carbone, F Karamalis, RA Flavell, JFAP Miller, ... Nature 393 (6684), 478-480, 1998 | 2789 | 1998 |
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway LE Otterbein, FH Bach, J Alam, M Soares, H Tao Lu, M Wysk, RJ Davis, ... Nature medicine 6 (4), 422-428, 2000 | 2697 | 2000 |
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity J Henao-Mejia, E Elinav, C Jin, L Hao, WZ Mehal, T Strowig, CA Thaiss, ... nature 482 (7384), 179-185, 2012 | 2692 | 2012 |
Recognition of single-stranded RNA viruses by Toll-like receptor 7 JM Lund, L Alexopoulou, A Sato, M Karow, NC Adams, NW Gale, ... Proceedings of the National Academy of Sciences 101 (15), 5598-5603, 2004 | 2529 | 2004 |
Inflammasomes in health and disease T Strowig, J Henao-Mejia, E Elinav, R Flavell nature 481 (7381), 278-286, 2012 | 2501 | 2012 |
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice K Kuida, TS Zheng, S Na, CY Kuan, D Yang, H Karasuyama, P Rakic, ... Nature 384 (6607), 368-372, 1996 | 2403 | 1996 |
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract KS Kobayashi, M Chamaillard, Y Ogura, O Henegariu, N Inohara, ... Science 307 (5710), 731-734, 2005 | 2249 | 2005 |
BCL-2, BCL-XL sequester BH3 domain-only molecules preventing BAX-and BAK-mediated mitochondrial apoptosis HYAC Emily, MC Wei, S Weiler, RA Flavell, TW Mak, T Lindsten, ... Molecular cell 8 (3), 705-711, 2001 | 2248 | 2001 |
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway C Tournier, P Hess, DD Yang, J Xu, TK Turner, A Nimnual, D Bar-Sagi, ... Science 288 (5467), 870-874, 2000 | 2200 | 2000 |
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis E Elinav, T Strowig, AL Kau, J Henao-Mejia, CA Thaiss, CJ Booth, ... Cell 145 (5), 745-757, 2011 | 2190 | 2011 |
MAP KINASES IN THE IMMUNE RESPONSE C Dong, RJ Davis, RA Flavell Annual review of immunology 20 (1), 55-72, 2002 | 2153 | 2002 |
CD40 and CD154 in cell-mediated immunity IS Grewal, RA Flavell Annual review of immunology 16 (1), 111-135, 1998 | 2140 | 1998 |
Reduced apoptosis and cytochrome c–mediated caspase activation in mice lacking caspase 9 K Kuida, TF Haydar, CY Kuan, Y Gu, C Taya, H Karasuyama, MSS Su, ... Cell 94 (3), 325-337, 1998 | 2090 | 1998 |
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms E Elinav, R Nowarski, CA Thaiss, B Hu, C Jin, RA Flavell Nature Reviews Cancer 13 (11), 759-771, 2013 | 2051 | 2013 |
Altered cytokine export and apoptosis in mice deficient in interleukin-1β converting enzyme K Kuida, JA Lippke, G Ku, MW Harding, DJ Livingston, MSS Su, ... science 267 (5206), 2000-2003, 1995 | 2051 | 1995 |
IRAK-M is a negative regulator of Toll-like receptor signaling K Kobayashi, LD Hernandez, JE Galán, CA Janeway, R Medzhitov, ... Cell 110 (2), 191-202, 2002 | 1847 | 2002 |
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants SC Eisenbarth, OR Colegio, W O’Connor, FS Sutterwala, RA Flavell Nature 453 (7198), 1122-1126, 2008 | 1807 | 2008 |