Lipid-chaperone hypothesis: A common molecular mechanism of membrane disruption by intrinsically disordered proteins MF Sciacca, F Lolicato, C Tempra, F Scollo, BR Sahoo, MD Watson, ... ACS chemical neuroscience 11 (24), 4336-4350, 2020 | 132 | 2020 |
Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways F Bellia, V Lanza, S García-Viñuales, IMM Ahmed, A Pietropaolo, ... Chemical science 10 (9), 2732-2742, 2019 | 54 | 2019 |
Trehalose conjugates of silybin as prodrugs for targeting toxic Aβ aggregates S García-Viñuales, R Ahmed, MFM Sciacca, V Lanza, ML Giuffrida, ... ACS Chemical Neuroscience 11 (17), 2566-2576, 2020 | 25 | 2020 |
The interplay between lipid and Aβ amyloid homeostasis in Alzheimer’s Disease: risk factors and therapeutic opportunities S García-Viñuales, MFM Sciacca, V Lanza, AM Santoro, G Grasso, ... Chemistry and Physics of Lipids 236, 105072, 2021 | 24 | 2021 |
Modulating Aβ aggregation by tyrosol-based ligands: The crucial role of the catechol moiety V Romanucci, S García-Viñuales, C Tempra, R Bernini, A Zarrelli, ... Biophysical Chemistry 265, 106434, 2020 | 24 | 2020 |
Silybins inhibit human IAPP amyloid growth and toxicity through stereospecific interactions S García-Viñuales, IM Ilie, AM Santoro, V Romanucci, A Zarrelli, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1870 (5), 140772, 2022 | 21 | 2022 |
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β‐Amyloid Toxicity AM Santoro, V Lanza, F Bellia, D Sbardella, GR Tundo, A Cannizzo, ... ChemMedChem 15 (3), 302-316, 2020 | 18 | 2020 |
Substitution of the native Zn (II) with Cd (II), Co (II) and Ni (II) changes the downhill unfolding mechanism of Ros87 to a completely different scenario R Grazioso, S García-Viñuales, L Russo, G D’Abrosca, S Esposito, ... International Journal of Molecular Sciences 21 (21), 8285, 2020 | 14 | 2020 |
Site directed mutagenesis of insulin-degrading enzyme allows singling out the molecular basis of peptidase versus E1-like activity: the role of metal ions F Bellia, V Lanza, IMM Ahmed, S Garcia-Vinuales, E Veiss, M Arizzi, ... Metallomics 11 (2), 278-281, 2019 | 13 | 2019 |
Endogenous and artificial miRNAs explore a rich variety of conformations: a potential relationship between secondary structure and biological functionality CMA Gangemi, S Alaimo, A Pulvirenti, S García-Viñuales, D Milardi, ... Scientific Reports 10 (1), 453, 2020 | 12 | 2020 |
Stereoselective ethynylation and propargylation of chiral cyclic nitrones: Application to the synthesis of glycomimetics S García-Viñuales, I Delso, P Merino, T Tejero Synthesis 48 (19), 3339-3351, 2016 | 12 | 2016 |
Synthesis of New Tyrosol‐Based Phosphodiester Derivatives: Effect on Amyloid β Aggregation and Metal Chelation Ability V Romanucci, M Giordano, G De Tommaso, M Iuliano, R Bernini, ... ChemMedChem 16 (7), 1172-1183, 2021 | 11 | 2021 |
Study of melamine-formaldehyde/phase change material microcapsules for the preparation of polymer films by extrusion S García-Viñuales, C Rubio, L Martínez-Izquierdo, B Zornoza, E Piera, ... Membranes 12 (3), 266, 2022 | 10 | 2022 |
Recent advances in the preparation of enantiomerically pure hydroxylamines from nitrones R Matute, S García-Viñuales, H Hayes, M Ghirardello, A Darù, T Tejero, ... Current Organic Synthesis 13 (5), 669-686, 2016 | 9 | 2016 |
The ionophoric activity of a pro-apoptotic VEGF165 fragment on HUVEC Cells S Zimbone, AM Santoro, D La Mendola, C Giacomelli, ML Trincavelli, ... International Journal of Molecular Sciences 21 (8), 2866, 2020 | 7 | 2020 |
Silybins are stereospecific regulators of the 20S proteasome M Persico, S García-Viñuales, AM Santoro, V Lanza, GR Tundo, ... Bioorganic & Medicinal Chemistry 66, 116813, 2022 | 6 | 2022 |
The change of conditions does not affect Ros87 downhill folding mechanism R Grazioso, S García-Viñuales, G D’Abrosca, I Baglivo, PV Pedone, ... Scientific Reports 10 (1), 21067, 2020 | 6 | 2020 |
Lipid-Chaperone Hypothesis: A Common Molecular Mechanism of Membrane Disruption by Intrinsically Disordered Proteins, ACS Chem Neurosci. 11 (2020) 4336–4350 MF Sciacca, F Lolicato, C Tempra, F Scollo, BR Sahoo, MD Watson, ... | 5 | |
Dipyridamole for tracking amyloidogenic proteins aggregation and enhancing polyubiquitination F Laneri, S García-Viñuales, V Lanza, N Licciardello, D Milardi, S Sortino, ... Archives of Biochemistry and Biophysics 728, 109354, 2022 | 4 | 2022 |
Structural characterization of the thermal unfolding pathway of human VEGFR1 D2 domain D Diana, R Di Stasi, S García‐Viñuales, L De Rosa, C Isernia, G Malgieri, ... The FEBS Journal 289 (6), 1591-1602, 2022 | 1 | 2022 |