An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA M Demaria, N Ohtani, SA Youssef, F Rodier, W Toussaint, JR Mitchell, ... Developmental cell 31 (6), 722-733, 2014 | 1944 | 2014 |
A telomerase component is defective in the human disease dyskeratosis congenita JR Mitchell, E Wood, K Collins Nature 402 (6761), 551-555, 1999 | 1483 | 1999 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 1149 | 2019 |
Telomerase in the human organism K Collins, JR Mitchell Oncogene 21 (4), 564-579, 2002 | 846 | 2002 |
Defective mitophagy in XPA via PARP-1 hyperactivation and NAD+/SIRT1 reduction EF Fang, M Scheibye-Knudsen, LE Brace, H Kassahun, T SenGupta, ... Cell 157 (4), 882-896, 2014 | 682 | 2014 |
A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3′ end JR Mitchell, J Cheng, K Collins Molecular and cellular biology 19 (1), 567-576, 1999 | 675 | 1999 |
Interventions to slow aging in humans: are we ready? VD Longo, A Antebi, A Bartke, N Barzilai, HM Brown‐Borg, C Caruso, ... Aging cell 14 (4), 497-510, 2015 | 643 | 2015 |
Endogenous hydrogen sulfide production is essential for dietary restriction benefits C Hine, E Harputlugil, Y Zhang, C Ruckenstuhl, BC Lee, L Brace, ... Cell 160 (1), 132-144, 2015 | 580 | 2015 |
Effects of sex, strain, and energy intake on hallmarks of aging in mice SJ Mitchell, J Madrigal-Matute, M Scheibye-Knudsen, E Fang, M Aon, ... Cell metabolism 23 (6), 1093-1112, 2016 | 450 | 2016 |
Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging A Das, GX Huang, MS Bonkowski, A Longchamp, C Li, MB Schultz, ... Cell 173 (1), 74-89. e20, 2018 | 432 | 2018 |
Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase JR Mitchell, K Collins Molecular cell 6 (2), 361-371, 2000 | 368 | 2000 |
The multidomain structure of Orc1 p reveals similarity to regulators of DNA replication and transcriptional silencing SP Bell, J Mitchell, J Leber, R Kobayashi, B Stillman Cell 83 (4), 563-568, 1995 | 351 | 1995 |
Selective persulfide detection reveals evolutionarily conserved antiaging effects of S-sulfhydration J Zivanovic, E Kouroussis, JB Kohl, B Adhikari, B Bursac, S Schott-Roux, ... Cell metabolism 30 (6), 1152-1170. e13, 2019 | 302 | 2019 |
Amino acid restriction triggers angiogenesis via GCN2/ATF4 regulation of VEGF and H2S production A Longchamp, T Mirabella, A Arduini, MR MacArthur, A Das, ... Cell 173 (1), 117-129. e14, 2018 | 297 | 2018 |
Short‐term dietary restriction and fasting precondition against ischemia reperfusion injury in mice JR Mitchell, M Verweij, K Brand, M Van De Ven, N Goemaere, ... Aging cell 9 (1), 40-53, 2010 | 283 | 2010 |
Impaired genome maintenance suppresses the growth hormone–insulin-like growth factor 1 axis in mice with Cockayne syndrome I Van Der Pluijm, GA Garinis, RMC Brandt, TGMF Gorgels, SW Wijnhoven, ... PLoS biology 5 (1), e2, 2007 | 274 | 2007 |
Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR J Gallinetti, E Harputlugil, JR Mitchell Biochemical Journal 449 (1), 1-10, 2013 | 273 | 2013 |
RNA binding domain of telomerase reverse transcriptase CK Lai, JR Mitchell, K Collins Molecular and cellular biology, 2001 | 255 | 2001 |
CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication L Zou, J Mitchell, B Stillman Molecular and cellular biology, 1997 | 237 | 1997 |
Divide and conquer: nucleotide excision repair battles cancer and ageing JR Mitchell, JHJ Hoeijmakers, LJ Niedernhofer Current opinion in cell biology 15 (2), 232-240, 2003 | 211 | 2003 |