| Tagging and detection strategies for activity-based proteomics AM Sadaghiani, SHL Verhelst, M Bogyo Current opinion in chemical biology 11 (1), 20-28, 2007 | 318 | 2007 |
| Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages GP Shi, RAR Bryant, R Riese, S Verhelst, C Driessen, Z Li, D Bromme, ... The Journal of experimental medicine 191 (7), 1177-1186, 2000 | 309 | 2000 |
| Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs M Bogyo, S Verhelst, V Bellingard-Dubouchaud, S Toba, D Greenbaum Chemistry & biology 7 (1), 27-38, 2000 | 281 | 2000 |
| ATP13A2 deficiency disrupts lysosomal polyamine export S van Veen, S Martin, C Van den Haute, V Benoy, J Lyons, R Vanhoutte, ... Nature 578 (7795), 419-424, 2020 | 256 | 2020 |
| A mild chemically cleavable linker system for functional proteomic applications SHL Verhelst, M Fonovic, M Bogyo Angew. Chem. Int. Ed 46 (8), 1284-1286, 2007 | 189 | 2007 |
| Activity‐based probes for the study of proteases: recent advances and developments S Serim, U Haedke, SHL Verhelst ChemMedChem 7 (7), 1146-1159, 2012 | 130 | 2012 |
| Proteomics evaluation of chemically cleavable activity-based probes M Fonovic, SHL Verhelst, MT Sorum, M Bogyo Molecular & Cellular Proteomics 6 (10), 1761-1770, 2007 | 118 | 2007 |
| The structural basis for catalysis and substrate specificity of a rhomboid protease KR Vinothkumar, K Strisovsky, A Andreeva, Y Christova, S Verhelst, ... The EMBO journal 29 (22), 3797-3809, 2010 | 117 | 2010 |
| Proteome-wide detection of S-nitrosylation targets and motifs using bioorthogonal cleavable-linker-based enrichment and switch technique R Mnatsakanyan, S Markoutsa, K Walbrunn, A Roos, SHL Verhelst, ... Nature communications 10 (1), 2195, 2019 | 104 | 2019 |
| Design, synthesis, and evaluation of in vivo potency and selectivity of epoxysuccinyl-based inhibitors of papain-family cysteine proteases AM Sadaghiani, SHL Verhelst, V Gocheva, K Hill, E Majerova, S Stinson, ... Chemistry & biology 14 (5), 499-511, 2007 | 90 | 2007 |
| Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspase F Schlauderer, K Lammens, D Nagel, M Vincendeau, AC Eitelhuber, ... Angewandte Chemie International Edition 52 (39), 10384-10387, 2013 | 83 | 2013 |
| A selective activity-based probe for the papain family cysteine protease dipeptidyl peptidase I/cathepsin C F Yuan, SHL Verhelst, G Blum, LM Coussens, M Bogyo Journal of the American Chemical Society 128 (17), 5616-5617, 2006 | 79 | 2006 |
| A simple and effective cleavable linker for chemical proteomics applications Y Yang, H Hahne, B Kuster, SHL Verhelst Molecular & Cellular Proteomics 12 (1), 237-244, 2013 | 77 | 2013 |
| Activity-based probes for rhomboid proteases discovered in a mass spectrometry-based assay O Vosyka, KR Vinothkumar, EV Wolf, AJ Brouwer, RMJ Liskamp, ... Proceedings of the National Academy of Sciences 110 (7), 2472-2477, 2013 | 75 | 2013 |
| Minitags for small molecules: detecting targets of reactive small molecules in living plant tissues using ‘click chemistry’ F Kaschani, SHL Verhelst, PF Van Swieten, M Verdoes, CS Wong, ... The Plant Journal 57 (2), 373-385, 2009 | 75 | 2009 |
| A Short route toward chiral, polyhydroxylated indolizidines and quinolizidines SHL Verhelst, B Paez Martinez, MSM Timmer, G Lodder, ... The Journal of Organic Chemistry 68 (25), 9598-9603, 2003 | 71 | 2003 |
| A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile … SA Beckham, D Piedrafita, CI Phillips, N Samarawickrema, RHP Law, ... The international journal of biochemistry & cell biology 41 (7), 1601-1612, 2009 | 68 | 2009 |
| ATP13A3 is a major component of the enigmatic mammalian polyamine transport system NN Hamouda, C Van den Haute, R Vanhoutte, R Sannerud, M Azfar, ... Journal of Biological Chemistry 296, 2021 | 66 | 2021 |
| Development of calpain-specific inactivators by screening of positional scanning epoxide libraries D Cuerrier, T Moldoveanu, RL Campbell, J Kelly, B Yoruk, SHL Verhelst, ... Journal of Biological Chemistry 282 (13), 9600-9611, 2007 | 59 | 2007 |
| Surface plasmon resonance evaluation of various aminoglycoside–RNA hairpin interactions reveals low degree of selectivity SHL Verhelst, PJA Michiels, GA van der Marel, CAA van Boeckel, ... ChemBioChem 5 (7), 937-942, 2004 | 59 | 2004 |
