Large deletions induced by Cas9 cleavage F Adikusuma, S Piltz, MA Corbett, M Turvey, SR McColl, KJ Helbig, ... Nature 560 (7717), E8-E9, 2018 | 355 | 2018 |
Analysis of ISG expression in chronic hepatitis C identifies viperin as a potential antiviral effector KJ Helbig, DTY Lau, L Semendric, HAJ Harley, MR Beard Hepatology 42 (3), 702-710, 2005 | 286 | 2005 |
HIV-1 infection of human macrophages directly induces viperin which inhibits viral production N Nasr, S Maddocks, SG Turville, AN Harman, N Woolger, KJ Helbig, ... Blood, The Journal of the American Society of Hematology 120 (4), 778-788, 2012 | 272 | 2012 |
The role of viperin in the innate antiviral response KJ Helbig, MR Beard Journal of molecular biology 426 (6), 1210-1219, 2014 | 255 | 2014 |
The antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5A KJ Helbig, NS Eyre, E Yip, S Narayana, K Li, G Fiches, EM McCartney, ... Hepatology 54 (5), 1506-1517, 2011 | 241 | 2011 |
Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin KJ Helbig, JM Carr, JK Calvert, S Wati, JN Clarke, NS Eyre, SK Narayana, ... PLoS neglected tropical diseases 7 (4), e2178, 2013 | 200 | 2013 |
Interferon-stimulated genes as enhancers of antiviral innate immune signaling KM Crosse, EA Monson, MR Beard, KJ Helbig Journal of innate immunity 10 (2), 85-93, 2018 | 195 | 2018 |
The interferon-induced transmembrane proteins, IFITM1, IFITM2, and IFITM3 inhibit hepatitis C virus entry SK Narayana, KJ Helbig, EM McCartney, NS Eyre, RA Bull, A Eltahla, ... Journal of Biological Chemistry 290 (43), 25946-25959, 2015 | 182 | 2015 |
Expression of the CXCR3 ligand I‐TAC by hepatocytes in chronic hepatitis C and its correlation with hepatic inflammation KJ Helbig, A Ruszkiewicz, L Semendric, HAJ Harley, SR McColl, ... Hepatology 39 (5), 1220-1229, 2004 | 147 | 2004 |
CD4+ T-Cell Deficiency in HIV Patients Responding to Antiretroviral Therapy Is Associated With Increased Expression of Interferon-Stimulated Genes in CD4+ T … S Fernandez, S Tanaskovic, K Helbig, R Rajasuriar, M Kramski, ... The Journal of infectious diseases 204 (12), 1927-1935, 2011 | 125 | 2011 |
Viperin is an important host restriction factor in control of Zika virus infection KH Van der Hoek, NS Eyre, B Shue, O Khantisitthiporn, K Glab-Ampi, ... Scientific reports 7 (1), 4475, 2017 | 122 | 2017 |
Lipid droplets and lipid mediators in viral infection and immunity EA Monson, AM Trenerry, JL Laws, JM Mackenzie, KJ Helbig FEMS microbiology reviews 45 (4), fuaa066, 2021 | 98 | 2021 |
Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response EA Monson, KM Crosse, M Duan, W Chen, RD O’shea, LM Wakim, ... Nature Communications 12 (1), 4303, 2021 | 94 | 2021 |
The Complex Diseases of Staphylococcus pseudintermedius in Canines: Where to Next? SA Lynch, KJ Helbig Veterinary sciences 8 (1), 11, 2021 | 90 | 2021 |
Differential expression of the CXCR3 ligands in chronic hepatitis C virus (HCV) infection and their modulation by HCV in vitro KJ Helbig, A Ruszkiewicz, RE Lanford, MD Berzsenyi, HA Harley, ... Journal of virology 83 (2), 836-846, 2009 | 85 | 2009 |
Alcohol metabolism increases the replication of hepatitis C virus and attenuates the antiviral action of interferon EM McCartney, L Semendric, KJ Helbig, S Hinze, B Jones, SA Weinman, ... The Journal of infectious diseases 198 (12), 1766-1775, 2008 | 77 | 2008 |
Genomic characterization of two novel pathogenic avipoxviruses isolated from pacific shearwaters (Ardenna spp.) S Sarker, S Das, JL Lavers, I Hutton, K Helbig, J Imbery, C Upton, ... BMC genomics 18, 1-26, 2017 | 66 | 2017 |
Signal transducer and activator of transcription 3 is a proviral host factor for hepatitis C virus EM McCartney, KJ Helbig, SK Narayana, NS Eyre, AL Aloia, MR Beard Hepatology 58 (5), 1558-1568, 2013 | 65 | 2013 |
Dynamic imaging of the hepatitis C virus NS5A protein during a productive infection NS Eyre, GN Fiches, AL Aloia, KJ Helbig, EM McCartney, CSP McErlean, ... Journal of virology 88 (7), 3636-3652, 2014 | 63 | 2014 |
Primed for success: Oyster parents treated with poly (I: C) produce offspring with enhanced protection against Ostreid herpesvirus type I infection TJ Green, K Helbig, P Speck, DA Raftos Molecular immunology 78, 113-120, 2016 | 62 | 2016 |