| Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells TN Seagroves, HE Ryan, H Lu, BG Wouters, M Knapp, P Thibault, ... Molecular and cellular biology, 2001 | 787 | 2001 |
| IKKα provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development Y Cao, G Bonizzi, TN Seagroves, FR Greten, R Johnson, EV Schmidt, ... Cell 107 (6), 763-775, 2001 | 608 | 2001 |
| Hypoxia-inducible factor-1α is a key regulator of metastasis in a transgenic model of cancer initiation and progression D Liao, C Corle, TN Seagroves, RS Johnson Cancer research 67 (2), 563-572, 2007 | 440 | 2007 |
| O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway CM Ferrer, TP Lynch, VL Sodi, JN Falcone, LP Schwab, DL Peacock, ... Molecular cell 54 (5), 820-831, 2014 | 419 | 2014 |
| C/EBPβ, but not C/EBPα, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland TN Seagroves, S Krnacik, B Raught, J Gay, B Burgess-Beusse, ... Genes & development 12 (12), 1917-1928, 1998 | 337 | 1998 |
| Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer LP Schwab, DL Peacock, D Majumdar, JF Ingels, LC Jensen, KD Smith, ... Breast Cancer Research 14, 1-25, 2012 | 270 | 2012 |
| The role of melanogenesis in regulation of melanoma behavior: Melanogenesis leads to stimulation of HIF-1α expression and HIF-dependent attendant pathways A Slominski, TK Kim, AA Brożyna, Z Janjetovic, DLP Brooks, LP Schwab, ... Archives of biochemistry and biophysics 563, 79-93, 2014 | 219 | 2014 |
| C/EBPβ (CCAAT/enhancer binding protein) controls cell fate determination during mammary gland development TN Seagroves, JP Lydon, RC Hovey, BK Vonderhaar, JM Rosen Molecular endocrinology 14 (3), 359-368, 2000 | 206 | 2000 |
| ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models DLP Brooks, LP Schwab, R Krutilina, DN Parke, A Sethuraman, ... Molecular cancer 15, 1-19, 2016 | 192 | 2016 |
| mTOR/MYC axis regulates O-GlcNAc transferase expression and O-GlcNAcylation in breast cancer VL Sodi, S Khaku, R Krutilina, LP Schwab, DJ Vocadlo, TN Seagroves, ... Molecular Cancer Research 13 (5), 923-933, 2015 | 148 | 2015 |
| Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development SL Grimm, TN Seagroves, EB Kabotyanski, RC Hovey, BK Vonderhaar, ... Molecular Endocrinology 16 (12), 2675-2691, 2002 | 148 | 2002 |
| Expression of the Rho-GEF Pbl/ECT2 is regulated by the UBE3A E3 ubiquitin ligase LT Reiter, TN Seagroves, M Bowers, E Bier Human molecular genetics 15 (18), 2825-2835, 2006 | 119 | 2006 |
| MicroRNA-18a inhibits hypoxia-inducible factor 1α activity and lung metastasis in basal breast cancers R Krutilina, W Sun, A Sethuraman, M Brown, TN Seagroves, LM Pfeffer, ... Breast Cancer Research 16, 1-16, 2014 | 115 | 2014 |
| HIF1α is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland TN Seagroves, D Hadsell, J McManaman, C Palmer, D Liao, W McNulty, ... Oxford University Press for The Company of Biologists Limited 130 (8), 1713-1724, 2003 | 103 | 2003 |
| The oncogene HER2/neu (ERBB2) requires the hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistance KA Whelan, LP Schwab, SV Karakashev, L Franchetti, GJ Johannes, ... Journal of Biological Chemistry 288 (22), 15865-15877, 2013 | 84 | 2013 |
| The Spy1/RINGO family represents a novel mechanism regulating mammary growth and tumorigenesis A Golipour, D Myers, T Seagroves, D Murphy, GI Evan, DJ Donoghue, ... Cancer Research 68 (10), 3591-3600, 2008 | 66 | 2008 |
| Activation of estrogen receptor alpha by decitabine inhibits osteosarcoma growth and metastasis MA Lillo Osuna, J Garcia-Lopez, I El Ayachi, I Fatima, AB Khalid, ... Cancer research 79 (6), 1054-1068, 2019 | 63 | 2019 |
| Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression TM Regan Anderson, DL Peacock, AR Daniel, GK Hubbard, KA Lofgren, ... Cancer research 73 (18), 5810-5820, 2013 | 63 | 2013 |
| The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer I Fatima, I El-Ayachi, L Taotao, MA Lillo, R Krutilina, TN Seagroves, ... PloS one 12 (12), e0189864, 2017 | 61 | 2017 |
| Methylparaben stimulates tumor initiating cells in ER+ breast cancer models MA Lillo, C Nichols, C Perry, S Runke, R Krutilina, TN Seagroves, ... Journal of Applied Toxicology 37 (4), 417-425, 2017 | 61 | 2017 |
Randall S. JohnsonUniversity of Cambridge and Karolinska Institutet and UC San DiegoEmail verificata su cam.ac.uk
