Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition IM Flyamer*, J Gassler*, M Imakaev*, HB Brandão, SV Ulianov, ... Nature 544 (7648), 110-114, 2017 | 739 | 2017 |
Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains SV Ulianov, EE Khrameeva, AA Gavrilov, IM Flyamer, P Kos, ... Genome research 26 (1), 70-84, 2016 | 390 | 2016 |
A mechanism of cohesin‐dependent loop extrusion organizes zygotic genome architecture J Gassler, HB Brandão, M Imakaev, IM Flyamer, S Ladstätter, ... The EMBO journal 36 (24), 3600-3618, 2017 | 355 | 2017 |
Developmentally regulated Shh expression is robust to TAD perturbations I Williamson, L Kane, PS Devenney, IM Flyamer, E Anderson, ... Development 146 (19), dev179523, 2019 | 155 | 2019 |
Coolpup.py: versatile pile-up analysis of Hi-C data IM Flyamer, RS Illingworth, WA Bickmore Bioinformatics 36 (10), 2980-2985, 2020 | 139 | 2020 |
A central role for canonical PRC1 in shaping the 3D nuclear landscape S Boyle*, IM Flyamer*, I Williamson, D Sengupta, WA Bickmore, ... Genes & development 34 (13-14), 931-949, 2020 | 115 | 2020 |
Nuclear lamina integrity is required for proper spatial organization of chromatin in Drosophila SV Ulianov, SA Doronin, EE Khrameeva, PI Kos, AV Luzhin, SS Starikov, ... Nature communications 10 (1), 1176, 2019 | 106 | 2019 |
DNA methylation directs polycomb-dependent 3D genome re-organization in naive pluripotency K McLaughlin*, IM Flyamer*, JP Thomson, HK Mjoseng, R Shukla, ... Cell reports 29 (7), 1974-1985. e6, 2019 | 96 | 2019 |
MCM complexes are barriers that restrict cohesin-mediated loop extrusion BJH Dequeker, MJ Scherr, HB Brandão, J Gassler, S Powell, I Gaspar, ... Nature 606 (7912), 197-203, 2022 | 92 | 2022 |
Cohesin is required for long-range enhancer action at the Shh locus L Kane, I Williamson, IM Flyamer, Y Kumar, RE Hill, LA Lettice, ... Nature structural & molecular biology 29 (9), 891-897, 2022 | 83* | 2022 |
Cooltools: Enabling high-resolution Hi-C analysis in Python Open2C, N Abdennur, S Abraham, G Fudenberg, IM Flyamer, ... PLOS Computational Biology 20 (5), e1012067, 2024 | 73* | 2024 |
Pairtools: from sequencing data to chromosome contacts Open2C, N Abdennur, G Fudenberg, IM Flyamer, AA Galitsyna, ... PLOS Computational Biology 20 (5), e1012164, 2024 | 55 | 2024 |
Order and stochasticity in the folding of individual Drosophila genomes SV Ulianov, VV Zakharova, AA Galitsyna, PI Kos, KE Polovnikov, ... Nature communications 12 (1), 41, 2021 | 54 | 2021 |
Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction S Gnan, IM Flyamer, KN Klein, E Castelli, A Rapp, A Maiser, N Chen, ... Nature communications 12 (1), 2910, 2021 | 51 | 2021 |
Bivalent promoter hypermethylation in cancer is linked to the H327me3/H3K4me3 ratio in embryonic stem cells DS Dunican, HK Mjoseng, L Duthie, IM Flyamer, WA Bickmore, ... BMC biology 18, 1-21, 2020 | 42 | 2020 |
Activation of the alpha-globin gene expression correlates with dramatic upregulation of nearby non-globin genes and changes in local and large-scale chromatin spatial structure SV Ulianov, AA Galitsyna, IM Flyamer, AK Golov, EE Khrameeva, ... Epigenetics & Chromatin 10, 1-19, 2017 | 26 | 2017 |
Quantitative differences in TAD border strength underly the TAD hierarchy in Drosophila chromosomes AV Luzhin*, IM Flyamer*, EE Khrameeva, SV Ulianov, SV Razin, ... Journal of cellular biochemistry 120 (3), 4494-4503, 2019 | 23 | 2019 |
Ultra-long-range interactions between active regulatory elements ET Friman, IM Flyamer, D Marenduzzo, S Boyle, WA Bickmore Genome Research 33 (8), 1269-1283, 2023 | 20 | 2023 |
C-TALE, a new cost-effective method for targeted enrichment of Hi-C/3C-seq libraries AK Golov, SV Ulianov, AV Luzhin, EP Kalabusheva, OL Kantidze, ... Methods 170, 48-60, 2020 | 17 | 2020 |
Bioframe: operations on genomic intervals in Pandas dataframes Open2C, N Abdennur, G Fudenberg, IM Flyamer, AA Galitsyna, ... Bioinformatics 40 (2), btae088, 2024 | 16 | 2024 |