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Timothy Hla
Timothy Hla
Professor, Harvard Medical School; Investigator, Boston Children's Hospital
Email verificata su childrens.harvard.edu - Home page
Titolo
Citata da
Citata da
Anno
Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition
DL Simmons, RM Botting, T Hla
Pharmacological reviews 56 (3), 387-437, 2004
23892004
Human cyclooxygenase-2 cDNA.
T Hla, K Neilson
Proceedings of the national academy of sciences 89 (16), 7384-7388, 1992
20701992
Expression of cyclooxygenase-1 and-2 in human colorectal cancer
H Sano, Y Kawahito, RL Wilder, A Hashiramoto, S Mukai, K Asai, ...
Cancer research 55 (17), 3785-3789, 1995
16401995
Edg-1, the G protein–coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
Y Liu, R Wada, T Yamashita, Y Mi, CX Deng, JP Hobson, HM Rosenfeldt, ...
The Journal of clinical investigation 106 (8), 951-961, 2000
14022000
Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate
MJ Lee, S Thangada, KP Claffey, N Ancellin, CH Liu, M Kluk, M Volpi, ...
Cell 99 (3), 301-312, 1999
12211999
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
MJ Lee, JR Van Brocklyn, S Thangada, CH Liu, AR Hand, R Menzeleev, ...
Science 279 (5356), 1552-1555, 1998
12211998
Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice
CH Liu, SH Chang, K Narko, OC Trifan, MT Wu, E Smith, C Haudenschild, ...
Journal of Biological Chemistry 276 (21), 18563-18569, 2001
11162001
Cyclooxygenase-1 and-2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids.
LJ Crofford, RL Wilder, AP Ristimäki, H Sano, EF Remmers, HR Epps, ...
The Journal of clinical investigation 93 (3), 1095-1101, 1994
9511994
Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells.
D Goldgaber, HW Harris, T Hla, T Maciag, RJ Donnelly, JS Jacobsen, ...
Proceedings of the National Academy of Sciences 86 (19), 7606-7610, 1989
7921989
Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: a potential mechanism for inflammatory angiogenesis
P Ben-Av, LJ Crofford, RL Wilder, T Hla
FEBS letters 372 (1), 83-87, 1995
7621995
Structure of the human cyclo-oxygenase-2 gene
SB Appleby, A Ristimäki, K Neilson, K Narko, T Hla
Biochemical Journal 302 (3), 723-727, 1994
7481994
Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M
C Christoffersen, H Obinata, SB Kumaraswamy, S Galvani, J Ahnström, ...
Proceedings of the National Academy of Sciences 108 (23), 9613-9618, 2011
6652011
Lysophospholipids--receptor revelations
T Hla, MJ Lee, N Ancellin, JH Paik, MJ Kluk
Science 294 (5548), 1875-1878, 2001
6652001
The nuclear receptor PPARγ and immunoregulation: PPARγ mediates inhibition of helper T cell responses
RB Clark, D Bishop-Bailey, T Estrada-Hernandez, T Hla, L Puddington, ...
The Journal of Immunology 164 (3), 1364-1371, 2000
6452000
An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors.
T Hla, T Maciag
Journal of Biological Chemistry 265 (16), 9308-9313, 1990
6201990
International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature
J Chun, EJ Goetzl, T Hla, Y Igarashi, KR Lynch, W Moolenaar, S Pyne, ...
Pharmacological reviews 54 (2), 265-269, 2002
6152002
Structural and functional characteristics of S1P receptors
T Sanchez, T Hla
Journal of cellular biochemistry 92 (5), 913-922, 2004
6132004
Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation.
A Ristimäki, S Garfinkel, J Wessendorf, T Maciag, T Hla
Journal of Biological Chemistry 269 (16), 11769-11775, 1994
6131994
Regulation of PTEN by Rho small GTPases
Z Li, X Dong, Z Wang, W Liu, N Deng, Y Ding, L Tang, T Hla, R Zeng, L Li, ...
Nature cell biology 7 (4), 399-404, 2005
6072005
Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells.
JA Maier, T Hla, T Maciag
Journal of Biological Chemistry 265 (19), 10805-10808, 1990
5971990
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