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Sylvain E. Lesné, PhD
Sylvain E. Lesné, PhD
Associate Professor of Neuroscience, University of Minnesota
Email verificata su umn.edu - Home page
Titolo
Citata da
Citata da
Anno
A specific amyloid-β protein assembly in the brain impairs memory.
S Lesné, MT Koh, L Kotilinek, R Kayed, CG Glabe, A Yang, M Gallagher, ...
Nature 440 (7082), 2006
35302006
Amyloid oligomers: A joint experimental/computational perspective on Alzheimer’s disease, Parkinson’s disease, type II diabetes, and amyotrophic lateral sclerosis
PH Nguyen, A Ramamoorthy, BR Sahoo, J Zheng, P Faller, JE Straub, ...
Chemical reviews 121 (4), 2545-2647, 2021
5322021
Brain amyloid-β oligomers in ageing and Alzheimer’s disease
SE Lesne, MA Sherman, M Grant, M Kuskowski, JA Schneider, ...
Brain 136 (5), 1383-1398, 2013
5282013
Accelerating amyloid-β fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models
IH Cheng, K Scearce-Levie, J Legleiter, JJ Palop, H Gerstein, N Bien-Ly, ...
Journal of Biological Chemistry 282 (33), 23818-23828, 2007
5182007
Soluble Aβ oligomer production and toxicity
ME Larson, SE Lesné
Journal of neurochemistry 120, 125-139, 2012
4752012
The complex PrPc-Fyn couples human oligomeric Aβ with pathological Tau changes in Alzheimer's disease
M Larson, MA Sherman, F Amar, M Nuvolone, JA Schneider, DA Bennett, ...
Journal of Neuroscience 32 (47), 16857-16871, 2012
3352012
Ischemia-induced interleukin-6 as a potential endogenous neuroprotective cytokine against NMDA receptor-mediated excitoxicity in the brain
C Ali, O Nicole, F Docagne, S Lesne, ET MacKenzie, A Nouvelot, ...
Journal of Cerebral Blood Flow & Metabolism 20 (6), 956-966, 2000
3182000
Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity
LA Kotilinek, MA Westerman, Q Wang, K Panizzon, GP Lim, A Simonyi, ...
Brain 131 (3), 651-664, 2008
2942008
NMDA receptor activation inhibits α-secretase and promotes neuronal amyloid-β production
S Lesné, C Ali, C Gabriel, N Croci, ET MacKenzie, CG Glabe, M Plotkine, ...
Journal of Neuroscience 25 (41), 9367-9377, 2005
2732005
Plaque-bearing mice with reduced levels of oligomeric amyloid-β assemblies have intact memory function
S Lesné, L Kotilinek, KH Ashe
Neuroscience 151 (3), 745-749, 2008
2412008
Orally available compound prevents deficits in memory caused by the Alzheimer amyloid‐β oligomers
M Townsend, JP Cleary, T Mehta, J Hofmeister, S Lesne, E O'Hare, ...
Annals of Neurology: Official Journal of the American Neurological …, 2006
2092006
Cognitive effects of cell-derived and synthetically derived Aβ oligomers
MN Reed, JJ Hofmeister, L Jungbauer, AT Welzel, C Yu, MA Sherman, ...
Neurobiology of aging 32 (10), 1784-1794, 2011
1752011
Transforming growth factor-β1 potentiates amyloid-β generation in astrocytes and in transgenic mice
S Lesné, F Docagne, C Gabriel, G Liot, DK Lahiri, L Buée, L Plawinski, ...
Journal of Biological Chemistry 278 (20), 18408-18418, 2003
1692003
Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology
ME Larson, MA Sherman, S Greimel, M Kuskowski, JA Schneider, ...
Journal of Neuroscience 32 (30), 10253-10266, 2012
1612012
Transforming growth factor-β and ischemic brain injury
A Buisson, S Lesne, F Docagne, C Ali, O Nicole, ET MacKenzie, D Vivien
Cellular and molecular neurobiology 23, 539-550, 2003
1582003
β-amyloid modulation of synaptic transmission and plasticity
DV Venkitaramani, J Chin, WJ Netzer, GK Gouras, S Lesne, R Malinow, ...
Journal of Neuroscience 27 (44), 11832-11837, 2007
1472007
Angiopoietin‐1‐induced phosphatidyl‐inositol 3‐kinase activation prevents neuronal apoptosis
S Valable, A Bellail, S Lesne, G Liot, ET Mackenzie, D Vivien, ...
The FASEB journal 17 (3), 1-19, 2003
1422003
Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity
H Ma, S Lesné, L Kotilinek, JV Steidl-Nichols, M Sherman, L Younkin, ...
Proceedings of the National Academy of Sciences 104 (19), 8167-8172, 2007
1382007
The amyloid-β oligomer Aβ* 56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation
F Amar, MA Sherman, T Rush, M Larson, G Boyle, L Chang, J Götz, ...
Science signaling 10 (478), eaal2021, 2017
1252017
Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-β1 against NMDA-induced necrosis
F Docagne, O Nicole, C Gabriel, M Fernández-Monreal, S Lesné, C Ali, ...
Molecular and Cellular Neuroscience 21 (4), 634-644, 2002
1072002
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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