The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans GTEx Consortium, KG Ardlie, DS Deluca, AV Segrè, TJ Sullivan, ... Science 348 (6235), 648-660, 2015 | 4775 | 2015 |
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3615 | 2010 |
Genetic effects on gene expression across human tissues GTEx Consortium Lead analysts: Aguet François 1 Brown Andrew A. 2 3 4 Castel ... Nature 550 (7675), 204-213, 2017 | 3551 | 2017 |
The GTEx Consortium atlas of genetic regulatory effects across human tissues GTEx Consortium Science 369 (6509), 1318-1330, 2020 | 3071 | 2020 |
Hundreds of variants clustered in genomic loci and biological pathways affect human height H Lango Allen, K Estrada, G Lettre, SI Berndt, MN Weedon, F Rivadeneira, ... Nature 467 (7317), 832-838, 2010 | 2355 | 2010 |
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC ... Nature genetics 44 (9), 981-990, 2012 | 2207 | 2012 |
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis BF Voight, LJ Scott, V Steinthorsdottir, AP Morris, C Dina, RP Welch, ... Nature genetics 42 (7), 579-589, 2010 | 2204 | 2010 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1923* | 2020 |
The human transcriptome across tissues and individuals M Melé, PG Ferreira, F Reverter, DS DeLuca, J Monlong, M Sammeth, ... Science 348 (6235), 660-665, 2015 | 1363 | 2015 |
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium Nature genetics 46 (3), 234-244, 2014 | 1022 | 2014 |
The Lin28/let-7 axis regulates glucose metabolism H Zhu, N Shyh-Chang, AV Segrè, G Shinoda, SP Shah, WS Einhorn, ... Cell 147 (1), 81-94, 2011 | 1010 | 2011 |
A novel approach to high-quality postmortem tissue procurement: the GTEx project LJ Carithers, K Ardlie, M Barcus, PA Branton, A Britton, SA Buia, ... Biopreservation and biobanking 13 (5), 311-319, 2015 | 889 | 2015 |
The impact of sex on gene expression across human tissues M Oliva, M Muñoz-Aguirre, S Kim-Hellmuth, V Wucher, ADH Gewirtz, ... Science 369 (6509), eaba3066, 2020 | 808 | 2020 |
Colocalization of GWAS and eQTL signals detects target genes F Hormozdiari, M Van De Bunt, AV Segre, X Li, JWJ Joo, M Bilow, JH Sul, ... The American Journal of Human Genetics 99 (6), 1245-1260, 2016 | 735 | 2016 |
Parental origin of sequence variants associated with complex diseases A Kong, V Steinthorsdottir, G Masson, G Thorleifsson, P Sulem, ... Nature 462 (7275), 868-874, 2009 | 669 | 2009 |
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies CE Elks, JRB Perry, P Sulem, DI Chasman, N Franceschini, C He, ... Nature genetics 42 (12), 1077-1085, 2010 | 618 | 2010 |
Dynamic landscape and regulation of RNA editing in mammals MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017 | 583 | 2017 |
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals Z Dastani, MF Hivert, N Timpson, JRB Perry, X Yuan, RA Scott, ... PLoS genetics 8 (3), e1002607, 2012 | 577 | 2012 |
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes J Flannick, G Thorleifsson, NL Beer, SBR Jacobs, N Grarup, NP Burtt, ... Nature genetics 46 (4), 357-363, 2014 | 555 | 2014 |
Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits AV Segrè, Diagram Consortium, Magic Investigators, L Groop, VK Mootha, ... PLoS genetics 6 (8), e1001058, 2010 | 553 | 2010 |