| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2671 | 2019 |
| Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 1011 | 2017 |
| A catalog of genetic loci associated with kidney function from analyses of a million individuals M Wuttke, Y Li, M Li, KB Sieber, MF Feitosa, M Gorski, A Tin, L Wang, ... Nature genetics 51 (6), 957-972, 2019 | 748 | 2019 |
| Susceptibility genes for age-related maculopathy on chromosome 10q26 J Jakobsdottir, YP Conley, DE Weeks, TS Mah, RE Ferrell, MB Gorin The American Journal of Human Genetics 77 (3), 389-407, 2005 | 706 | 2005 |
| Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration W Chen, D Stambolian, AO Edwards, KE Branham, M Othman, ... Proceedings of the National Academy of Sciences 107 (16), 7401-7406, 2010 | 622 | 2010 |
| Exome-wide association study of plasma lipids in> 300,000 individuals DJ Liu, GM Peloso, H Yu, AS Butterworth, X Wang, A Mahajan, ... Nature genetics 49 (12), 1758-1766, 2017 | 590 | 2017 |
| Co-regulatory networks of human serum proteins link genetics to disease V Emilsson, M Ilkov, JR Lamb, N Finkel, EF Gudmundsson, R Pitts, ... Science 361 (6404), 769-773, 2018 | 543 | 2018 |
| Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks GM Peloso, PL Auer, JC Bis, A Voorman, AC Morrison, NO Stitziel, ... The American Journal of Human Genetics 94 (2), 223-232, 2014 | 390 | 2014 |
| Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels A Tin, J Marten, VL Halperin Kuhns, Y Li, M Wuttke, H Kirsten, KB Sieber, ... Nature genetics 51 (10), 1459-1474, 2019 | 357 | 2019 |
| Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers J Jakobsdottir, MB Gorin, YP Conley, RE Ferrell, DE Weeks PLoS genetics 5 (2), e1000337, 2009 | 326 | 2009 |
| A novel Alzheimer disease locus located near the gene encoding tau protein G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ... Molecular psychiatry 21 (1), 108-117, 2016 | 311 | 2016 |
| Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci C Liu, AT Kraja, JA Smith, JA Brody, N Franceschini, JC Bis, K Rice, ... Nature genetics 48 (10), 1162-1170, 2016 | 286 | 2016 |
| Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol LA Lange, Y Hu, H Zhang, C Xue, EM Schmidt, ZZ Tang, C Bizon, ... The American Journal of Human Genetics 94 (2), 233-245, 2014 | 239 | 2014 |
| Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility J Wessel, AY Chu, SM Willems, S Wang, H Yaghootkar, JA Brody, ... Nature communications 6 (1), 5897, 2015 | 236 | 2015 |
| Candidate gene analysis suggests a role for fatty acid biosynthesis and regulation of the complement system in the etiology of age-related maculopathy YP Conley, A Thalamuthu, J Jakobsdottir, DE Weeks, T Mah, RE Ferrell, ... Human molecular genetics 14 (14), 1991-2002, 2005 | 225 | 2005 |
| CFH, ELOVL4, PLEKHA1 and LOC387715 genes and susceptibility to age-related maculopathy: AREDS and CHS cohorts and meta-analyses YP Conley, J Jakobsdottir, T Mah, DE Weeks, R Klein, L Kuller, RE Ferrell, ... Human molecular genetics 15 (21), 3206-3218, 2006 | 201 | 2006 |
| Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria A Teumer, Y Li, S Ghasemi, BP Prins, M Wuttke, T Hermle, A Giri, ... Nature communications 10 (1), 4130, 2019 | 187 | 2019 |
| Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study I Magnúsdóttir, A Lovik, AB Unnarsdóttir, D McCartney, H Ask, K Kõiv, ... The Lancet Public Health 7 (5), e406-e416, 2022 | 161 | 2022 |
| C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes J Jakobsdottir, YP Conley, DE Weeks, RE Ferrell, MB Gorin PloS one 3 (5), e2199, 2008 | 129 | 2008 |
| Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium A Moayyeri, YH Hsu, D Karasik, K Estrada, SM Xiao, C Nielson, ... Human molecular genetics 23 (11), 3054-3068, 2014 | 113 | 2014 |
Daniel E. WeeksProfessor of Human Genetics and Biostatistics, University of PittsburghEmail verificata su pitt.edu