| Regulation of pH by carbonic anhydrase 9 mediates survival of pancreatic cancer cells with activated KRAS in response to hypoxia PC McDonald, SC Chafe, WS Brown, S Saberi, M Swayampakula, ... Gastroenterology 157 (3), 823-837, 2019 | 190 | 2019 |
| An Organotrifluoroborate for Broadly Applicable One‐Step 18F‐Labeling Z Liu, M Pourghiasian, MA Radtke, J Lau, J Pan, GM Dias, D Yapp, KS Lin, ... Angewandte Chemie 126 (44), 12070-12074, 2014 | 187 | 2014 |
| Autophagy inhibition augments the anticancer effects of epirubicin treatment in anthracycline-sensitive and-resistant triple-negative breast cancer S Chittaranjan, S Bortnik, WH Dragowska, J Xu, N Abeysundara, A Leung, ... Clinical Cancer Research 20 (12), 3159-3173, 2014 | 166 | 2014 |
| Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK) LA Edwards, J Woo, LA Huxham, M Verreault, WH Dragowska, G Chiu, ... Molecular cancer therapeutics 7 (1), 59-70, 2008 | 105 | 2008 |
| RGD conjugates of the H2dedpa scaffold: synthesis, labeling and imaging with 68Ga E Boros, CL Ferreira, DTT Yapp, RK Gill, EW Price, MJ Adam, C Orvig Nuclear medicine and biology 39 (6), 785-794, 2012 | 95 | 2012 |
| Metronomic gemcitabine suppresses tumour growth, improves perfusion, and reduces hypoxia in human pancreatic ductal adenocarcinoma KKY Cham, JHE Baker, KS Takhar, JA Flexman, MQ Wong, DA Owen, ... British journal of cancer 103 (1), 52-60, 2010 | 95 | 2010 |
| Increasing the Bioavailability of RuIII Anticancer Complexes through Hydrophobic Albumin Interactions MI Webb, B Wu, T Jang, RA Chard, EWY Wong, MQ Wong, DTT Yapp, ... Chemistry–A European Journal 19 (50), 17031-17042, 2013 | 81 | 2013 |
| Evaluation of novel bifunctional chelates for the development of Cu-64-based radiopharmaceuticals CL Ferreira, DT Yapp, E Lamsa, M Gleave, C Bensimon, P Jurek, ... Nuclear medicine and biology 35 (8), 875-882, 2008 | 75 | 2008 |
| Kit-like 18F-labeling of RGD-19F-arytrifluroborate in high yield and at extraordinarily high specific activity with preliminary in vivo tumor imaging Z Liu, Y Li, J Lozada, MQ Wong, J Greene, KS Lin, D Yapp, DM Perrin Nuclear medicine and biology 40 (6), 841-849, 2013 | 70 | 2013 |
| Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin … M Verreault, D Strutt, D Masin, M Anantha, A Yung, P Kozlowski, ... BMC cancer 11, 1-18, 2011 | 70 | 2011 |
| Irinophore C, a novel nanoformulation of irinotecan, alters tumor vascular function and enhances the distribution of 5-fluorouracil and doxorubicin JHE Baker, J Lam, AH Kyle, J Sy, T Oliver, SJ Co, WH Dragowska, ... Clinical Cancer Research 14 (22), 7260-7271, 2008 | 68 | 2008 |
| 68Ga Small Peptide Imaging: Comparison of NOTA and PCTA CL Ferreira, DTT Yapp, D Mandel, RK Gill, E Boros, MQ Wong, P Jurek, ... Bioconjugate Chemistry 23 (11), 2239-2246, 2012 | 64 | 2012 |
| Comparison of bifunctional chelates for 64Cu antibody imaging CL Ferreira, DTT Yapp, S Crisp, BW Sutherland, SSW Ng, M Gleave, ... European Journal of Nuclear Medicine and Molecular Imaging 37, 2117-2126, 2010 | 60 | 2010 |
| Characterization of cationic liposome formulations designed to exhibit extended plasma residence times and tumor vasculature targeting properties EA Ho, E Ramsay, M Ginj, M Anantha, I Bregman, J Sy, J Woo, ... Journal of Pharmaceutical Sciences 99 (6), 2839-2853, 2010 | 59 | 2010 |
| Dual Mode Fluorescent 18F-PET Tracers: Efficient Modular Synthesis of Rhodamine-[cRGD]2-[18F]-Organotrifluoroborate, Rapid, and High Yielding One-Step 18F-Labeling at High … Z Liu, MA Radtke, MQ Wong, KS Lin, DT Yapp, DM Perrin Bioconjugate Chemistry 25 (11), 1951-1962, 2014 | 58 | 2014 |
| Functional imaging of oxidative stress with a novel PET imaging agent, 18F-5-fluoro-L-aminosuberic acid JM Webster, CA Morton, BF Johnson, H Yang, MJ Rishel, BD Lee, Q Miao, ... Journal of Nuclear Medicine 55 (4), 657-664, 2014 | 57 | 2014 |
| Induction of cytotoxicity in pyridine analogues of the anti-metastatic Ru (III) complex NAMI-A by ferrocene functionalization C Mu, SW Chang, KE Prosser, AWY Leung, S Santacruz, T Jang, ... Inorganic chemistry 55 (1), 177-190, 2016 | 50 | 2016 |
| Development and assessment of conventional and targeted drug combinations for use in the treatment of aggressive breast cancers DN Waterhouse, KA Gelmon, R Klasa, K Chi, D Huntsman, E Ramsay, ... Current cancer drug targets 6 (6), 455-489, 2006 | 50 | 2006 |
| Lansium domesticum: skin and leaf extracts of this fruit tree interrupt the lifecycle of Plasmodium falciparum, and are active towards a chloroquine-resistant strain of the … DTT Yapp, SY Yap Journal of Ethnopharmacology 85 (1), 145-150, 2003 | 50 | 2003 |
| The phosphoinositide-dependent kinase-1 inhibitor 2-amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] phenyl]-acetamide (OSU-03012) prevents Y-box binding … K To, Y Zhao, H Jiang, K Hu, M Wang, J Wu, C Lee, DW Yokom, ... Molecular pharmacology 72 (3), 641-652, 2007 | 46 | 2007 |
Jennifer H.E. BakerStaff Scientist, BC Cancer Agency Vancouver UBCEmail verificata su bccrc.ca