High-resolution TADs reveal DNA sequences underlying genome organization in flies F Ramírez, V Bhardwaj, L Arrigoni, KC Lam, BA Grüning, J Villaveces, ... Nature communications 9 (1), 189, 2018 | 770 | 2018 |
PrimeDesign software for rapid and simplified design of prime editing guide RNAs JY Hsu, J Grünewald, R Szalay, J Shih, AV Anzalone, KC Lam, MW Shen, ... Nature Communications 12 (1), 1034, 2021 | 160 | 2021 |
The NSL Complex Regulates Housekeeping Genes in Drosophila KC Lam, F Muehlpfordt, JM Vaquerizas, SJ Raja, H Holz, NM Luscombe, ... PLoS genetics 8 (6), e1002736, 2012 | 113 | 2012 |
High-affinity sites form an interaction network to facilitate spreading of the MSL complex across the X chromosome in Drosophila F Ramirez, T Lingg, S Toscano, KC Lam, P Georgiev, HR Chung, ... Molecular cell 60 (1), 146-162, 2015 | 92 | 2015 |
The NSL complex-mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise KC Lam, HR Chung, G Semplicio, SS Iyer, A Gaub, V Bhardwaj, H Holz, ... Genes & Development 33 (7-8), 452-465, 2019 | 18 | 2019 |
MOSAIC enables in situ saturation mutagenesis of genes and CRISPR prime editing guide RNA optimization in human cells JY Hsu, KC Lam, J Shih, L Pinello, JK Joung bioRxiv, 2024.04. 25.591078, 2024 | | 2024 |
CRISPR PERSIST-On enables heritable and fine-tunable human gene activation YE Tak, JY Hsu, J Shih, HT Schultz, IT Nguyen, KC Lam, L Pinello, ... bioRxiv, 2024.04. 26.590475, 2024 | | 2024 |
MOSAIC Enables In Situ Saturation Mutagenesis of Genes and Optimization of CRISPR Prime Editor Activities in Human Cells JY Hsu, KC Lam, JY Shih, L Pinello, K Joung MOLECULAR THERAPY 30 (5), 2-2, 2022 | | 2022 |