| Design, synthesis, and biological evaluation of a robust, biodegradable dendrimer DG Van Der Poll, HM Kieler-Ferguson, WC Floyd, SJ Guillaudeu, K Jerger, ... Bioconjugate chemistry 21 (4), 764-773, 2010 | 123 | 2010 |
| Anti-tumor activity of liposome encapsulated fluoroorotic acid as a single agent and in combination with liposome irinotecan K Riviere, HM Kieler-Ferguson, K Jerger, FC Szoka Jr Journal of controlled release 153 (3), 288-296, 2011 | 78 | 2011 |
| Clinical developments of chemotherapeutic nanomedicines: polymers and liposomes for delivery of camptothecins and platinum (II) drugs HM Kieler‐Ferguson, JMJ Fréchet, FC Szoka Jr Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 5 (2 …, 2013 | 59 | 2013 |
| Discovery of potent and orally available bicyclo [1.1. 1] pentane-derived indoleamine-2, 3-dioxygenase 1 (IDO1) inhibitors Q Pu, H Zhang, L Guo, M Cheng, AC Doty, H Ferguson, X Fradera, ... ACS Medicinal Chemistry Letters 11 (8), 1548-1554, 2020 | 58 | 2020 |
| Inhibition of RORγT skews TCRα gene rearrangement and limits T cell repertoire diversity Y Guo, KD MacIsaac, Y Chen, RJ Miller, R Jain, B Joyce-Shaikh, ... Cell reports 17 (12), 3206-3218, 2016 | 54 | 2016 |
| Encapsulation, controlled release, and antitumor efficacy of cisplatin delivered in liposomes composed of sterol-modified phospholipids HM Kieler-Ferguson, D Chan, J Sockolosky, L Finney, E Maxey, S Vogt, ... European Journal of Pharmaceutical Sciences 103, 85-93, 2017 | 47 | 2017 |
| Discovery of amino-cyclobutarene-derived indoleamine-2, 3-dioxygenase 1 (IDO1) inhibitors for cancer immunotherapy H Zhang, K Liu, Q Pu, A Achab, MJ Ardolino, M Cheng, Y Deng, AC Doty, ... ACS medicinal chemistry letters 10 (11), 1530-1536, 2019 | 43 | 2019 |
| Combination of EP4 antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells Y Wang, L Cui, P Georgiev, L Singh, Y Zheng, Y Yu, J Grein, C Zhang, ... Oncoimmunology 10 (1), 1896643, 2021 | 42 | 2021 |
| Chemotherapeutic evaluation of a synthetic tubulysin analogue–dendrimer conjugate in c26 tumor bearing mice WC Floyd III, GK Datta, S Imamura, HM Kieler‐Ferguson, K Jerger, ... ChemMedChem 6 (1), 49-53, 2011 | 41 | 2011 |
| The NLRP3 inflammasome mediates DSS-induced intestinal inflammation in Nod2 knockout mice B Umiker, HH Lee, J Cope, NJ Ajami, JP Laine, C Fregeau, H Ferguson, ... Innate Immunity 25 (2), 132-143, 2019 | 33 | 2019 |
| Development of high-throughput assays for evaluation of hematopoietic progenitor kinase 1 inhibitors BM Lacey, Z Xu, X Chai, J Laskey, X Fradera, P Mittal, S Mishra, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (1), 88-99, 2021 | 27 | 2021 |
| Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation GF Smith, MD Altman, B Andresen, J Baker, JD Brubaker, H Chen, ... Bioorganic & medicinal chemistry letters 27 (12), 2721-2726, 2017 | 27 | 2017 |
| Carbamate and N-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors D Li, Y Deng, A Achab, I Bharathan, BA Hopkins, W Yu, H Zhang, ... ACS medicinal chemistry letters 12 (3), 389-396, 2021 | 20 | 2021 |
| Discovery of N-(Indazol-3-yl)piperidine-4-carboxylic Acids as RORγt Allosteric Inhibitors for Autoimmune Diseases H Zhang, BT Lapointe, N Anthony, R Azevedo, J Cals, CC Correll, ... ACS Medicinal Chemistry Letters 11 (2), 114-119, 2020 | 20 | 2020 |
| Racemic iron (iii) and cobalt (iii) complexes containing a new pentadentate “helmet” phthalocyaninato ligand HM Kieler, MJ Bierman, IA Guzei, PJ Liska, RW McGaff Chemical communications, 3326-3328, 2006 | 20 | 2006 |
| Why magnesium is five-coordinate in methanol (phthalocyaninato) magnesium (II) IA Guzei, RW McGaff, HM Kieler Acta Crystallographica Section C: Crystal Structure Communications 61 (11 …, 2005 | 20 | 2005 |
| A robust and quantitative method for tracking liposome contents after intravenous administration AG Kohli, HM Kieler-Ferguson, D Chan, FC Szoka Journal of Controlled Release 176, 86-93, 2014 | 19 | 2014 |
| Oxetane promise delivered: discovery of long-acting IDO1 inhibitors suitable for Q3W oral or parenteral dosing D Li, DL Sloman, A Achab, H Zhou, MA McGowan, C White, C Gibeau, ... Journal of Medicinal Chemistry 65 (8), 6001-6016, 2022 | 13 | 2022 |
| Hierarchical particle approach for co-precipitated amorphous solid dispersions for use in preclinical in vivo studies L Schenck, C Boyce, D Frank, S Koranne, HM Ferguson, N Strotman Pharmaceutics 13 (7), 1034, 2021 | 13 | 2021 |
| Flexibility in drug product development: a perspective Y Kapoor, RF Meyer, HM Ferguson, D Skomski, P Daublain, GM Troup, ... Molecular Pharmaceutics 18 (7), 2455-2469, 2021 | 11 | 2021 |
