Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance A Limmer, J Ohl, C Kurts, HG Ljunggren, Y Reiss, M Groettrup, ... Nature medicine 6 (12), 1348-1354, 2000 | 906 | 2000 |
A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis T Muchamuel, M Basler, MA Aujay, E Suzuki, KW Kalim, C Lauer, ... Nature medicine 15 (7), 781-787, 2009 | 697 | 2009 |
Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells E Scandella, Y Men, S Gillessen, R Förster, M Groettrup Blood, The Journal of the American Society of Hematology 100 (4), 1354-1361, 2002 | 656 | 2002 |
Immuno-and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity EM Huber, M Basler, R Schwab, W Heinemeyer, CJ Kirk, M Groettrup, ... Cell 148 (4), 727-738, 2012 | 564 | 2012 |
Analysis and expression of a cloned pre-T cell receptor gene C Saint-Ruf, K Ungewiss, M Groettrup, L Bruno, HJ Fehling, ... Science 266 (5188), 1208-1212, 1994 | 527 | 1994 |
A role for the proteasome regulator PA28α in antigen presentation M Groettrup, A Soza, M Eggers, L Kuehn, TP Dick, H Schild, ... Nature 381 (6578), 166-168, 1996 | 463 | 1996 |
A novel disulfide-linked heterodimer on pre—T cells consists of the T cell receptor β chain and a 33 kd glycoprotein M Groettrup, K Ungewiss, O Azogui, R Palacios, MJ Owen, AC Hayday, ... Cell 75 (2), 283-294, 1993 | 442 | 1993 |
Proteasomes in immune cells: more than peptide producers? M Groettrup, CJ Kirk, M Basler Nature Reviews Immunology 10 (1), 73-78, 2010 | 422 | 2010 |
Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands TP Dick, T Ruppert, M Groettrup, PM Kloetzel, L Kuehn, UH Koszinowski, ... Cell 86 (2), 253-262, 1996 | 378 | 1996 |
An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses P Andre, M Groettrup, P Klenerman, R De Giuli, BL Booth Jr, V Cerundolo, ... Proceedings of the National Academy of Sciences 95 (22), 13120-13124, 1998 | 358 | 1998 |
TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses E Schlosser, M Mueller, S Fischer, S Basta, DH Busch, B Gander, ... Vaccine 26 (13), 1626-1637, 2008 | 355 | 2008 |
The immunoproteasome in antigen processing and other immunological functions M Basler, CJ Kirk, M Groettrup Current opinion in immunology 25 (1), 74-80, 2013 | 317 | 2013 |
The Interferon-γ-inducible 11 S Regulator (PA28) and the LMP2/LMP7 Subunits Govern the Peptide Production by the 20 S Proteasome in Vitro (∗) M Groettrup, T Ruppert, L Kuehn, M Seeger, S Standera, U Koszinowski, ... Journal of Biological Chemistry 270 (40), 23808-23815, 1995 | 312 | 1995 |
The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome M Groettrup, S Standera, R Stohwasser, PM Kloetzel Proceedings of the National Academy of Sciences 94 (17), 8970-8975, 1997 | 307 | 1997 |
CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2 E Scandella, Y Men, DF Legler, S Gillessen, L Prikler, B Ludewig, ... Blood 103 (5), 1595-1601, 2004 | 305 | 2004 |
Prevention of experimental colitis by a selective inhibitor of the immunoproteasome M Basler, M Dajee, C Moll, M Groettrup, CJ Kirk The Journal of Immunology 185 (1), 634-641, 2010 | 303 | 2010 |
Peptide antigen production by the proteasome: complexity provides efficiency M Groettrup, A Soza, U Kuckelkorn, PM Kloetzel Immunology today 17 (9), 429-435, 1996 | 288 | 1996 |
A third interferon‐γ‐induced subunit exchange in the 20S proteasome M Groettrup, R Kraft, S Kostka, S Standera, R Stohwasser, PM Kloetzel European journal of immunology 26 (4), 863-869, 1996 | 270 | 1996 |
Posttraumatic stress disorder is associated with an enhanced spontaneous production of pro-inflammatory cytokines by peripheral blood mononuclear cells H Gola, H Engler, A Sommershof, H Adenauer, S Kolassa, M Schedlowski, ... BMC psychiatry 13, 1-8, 2013 | 264 | 2013 |
Prostaglandin E2 is generally required for human dendritic cell migration and exerts its effect via EP2 and EP4 receptors DF Legler, P Krause, E Scandella, E Singer, M Groettrup The Journal of Immunology 176 (2), 966-973, 2006 | 260 | 2006 |