| Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism RM Perera, S Stoykova, BN Nicolay, KN Ross, J Fitamant, M Boukhali, ... Nature 524 (7565), 361-365, 2015 | 797 | 2015 |
| Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate L Bunse, S Pusch, T Bunse, F Sahm, K Sanghvi, M Friedrich, D Alansary, ... Nature medicine 24 (8), 1192-1203, 2018 | 468 | 2018 |
| The metabolic function of cyclin D3–CDK6 kinase in cancer cell survival H Wang, BN Nicolay, JM Chick, X Gao, Y Geng, H Ren, H Gao, G Yang, ... Nature 546 (7658), 426-430, 2017 | 336 | 2017 |
| Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers E Mullarky, NC Lucki, R Beheshti Zavareh, JL Anglin, AP Gomes, ... Proceedings of the National Academy of Sciences 113 (7), 1778-1783, 2016 | 313 | 2016 |
| LKB1 loss links serine metabolism to DNA methylation and tumorigenesis F Kottakis, BN Nicolay, A Roumane, R Karnik, H Gu, JM Nagle, ... Nature 539 (7629), 390-395, 2016 | 309 | 2016 |
| Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML S Choe, H Wang, CD DiNardo, EM Stein, S de Botton, GJ Roboz, ... Blood advances 4 (9), 1894-1905, 2020 | 163 | 2020 |
| Vorasidenib (AG-881): a first-in-class, brain-penetrant dual inhibitor of mutant IDH1 and 2 for treatment of glioma Z Konteatis, E Artin, B Nicolay, K Straley, AK Padyana, L Jin, Y Chen, ... ACS Medicinal Chemistry Letters 11 (2), 101-107, 2020 | 145 | 2020 |
| E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis PD Denechaud, IC Lopez-Mejia, A Giralt, Q Lai, E Blanchet, ... The Journal of clinical investigation 126 (1), 137-150, 2016 | 133 | 2016 |
| CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers AM Heilmann, RM Perera, V Ecker, BN Nicolay, N Bardeesy, CH Benes, ... Cancer research 74 (14), 3947-3958, 2014 | 119 | 2014 |
| Loss of RBF1 changes glutamine catabolism BN Nicolay, PA Gameiro, K Tschöp, M Korenjak, AM Heilmann, JM Asara, ... Genes & development 27 (2), 182-196, 2013 | 98 | 2013 |
| Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation BN Nicolay, PS Danielian, F Kottakis, JD Lapek, I Sanidas, WO Miles, ... Genes & development 29 (17), 1875-1889, 2015 | 96 | 2015 |
| Suppression of genome instability in pRB-deficient cells by enhancement of chromosome cohesion AL Manning, SA Yazinski, B Nicolay, A Bryll, L Zou, NJ Dyson Molecular cell 53 (6), 993-1004, 2014 | 93 | 2014 |
| Cocaine-mediated enhancement of virus replication in macrophages: Implications for human immunodeficiency virus–associated dementia NK Dhillon, R Williams, F Peng, Y Tsai, S Dhillon, B Nicolay, M Gadgil, ... Journal of neurovirology 13 (6), 483-495, 2007 | 92 | 2007 |
| Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia L Stuani, M Sabatier, E Saland, G Cognet, N Poupin, C Bosc, FA Castelli, ... Journal of Experimental Medicine 218 (5), e20200924, 2021 | 87 | 2021 |
| Mutant IDH inhibits IFNγ–TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma MJ Wu, L Shi, J Dubrot, J Merritt, V Vijay, TY Wei, E Kessler, KE Olander, ... Cancer discovery 12 (3), 812-835, 2022 | 86 | 2022 |
| The multiple connections between pRB and cell metabolism BN Nicolay, NJ Dyson Current opinion in cell biology 25 (6), 735-740, 2013 | 86 | 2013 |
| Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit BN Nicolay, B Bayarmagnai, AB Islam, N Lopez-Bigas, MV Frolov Genes & development 25 (4), 323-335, 2011 | 64 | 2011 |
| Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous MTAP Deletion Z Konteatis, J Travins, S Gross, K Marjon, A Barnett, E Mandley, B Nicolay, ... Journal of Medicinal Chemistry 64 (8), 4430-4449, 2021 | 56 | 2021 |
| Combined Inactivation of pRB and Hippo Pathways Induces Dedifferentiation in the Drosophila Retina BN Nicolay, B Bayarmagnai, NS Moon, EV Benevolenskaya, MV Frolov PLoS genetics 6 (4), e1000918, 2010 | 56 | 2010 |
| Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy BS Nelson, L Lin, DM Kremer, CM Sousa, C Cotta-Ramusino, A Myers, ... Cancer & metabolism 8, 1-16, 2020 | 37 | 2020 |