Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion F Yu, J Li, H Chen, J Fu, S Ray, S Huang, H Zheng, W Ai Oncogene 30 (18), 2161-2172, 2011 | 526 | 2011 |
Early-onset colorectal cancer: initial clues and current views LJ Hofseth, JR Hebert, A Chanda, H Chen, BL Love, MM Pena, ... Nature reviews Gastroenterology & hepatology 17 (6), 352-364, 2020 | 356 | 2020 |
HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition X Wu, H Chen, B Parker, E Rubin, T Zhu, JS Lee, P Argani, S Sukumar Cancer research 66 (19), 9527-9534, 2006 | 253 | 2006 |
CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin–TGFβ signaling PK Lo, D Kanojia, X Liu, UP Singh, FG Berger, Q Wang, H Chen Oncogene 31 (21), 2614-2626, 2012 | 231 | 2012 |
Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway X Zhang, G Wan, S Mlotshwa, V Vance, FG Berger, H Chen, X Lu Cancer research 70 (18), 7176-7186, 2010 | 187 | 2010 |
HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8 H Chen, S Chung, S Sukumar Molecular and cellular biology, 2004 | 170 | 2004 |
In vitro tumorsphere formation assays S Johnson, H Chen, PK Lo Bio-protocol 3 (3), e325-e325, 2013 | 132 | 2013 |
A role for the HOXB7 homeodomain protein in DNA repair E Rubin, X Wu, T Zhu, JCY Cheung, H Chen, A Lorincz, RK Pandita, ... Cancer research 67 (4), 1527-1535, 2007 | 121 | 2007 |
Role of homeobox genes in normal mammary gland development and breast tumorigenesis H Chen, S Sukumar Journal of mammary gland biology and neoplasia 8, 159-175, 2003 | 110 | 2003 |
Electrospun fibrous scaffolds promote breast cancer cell alignment and epithelial–mesenchymal transition S Saha, X Duan, L Wu, PK Lo, H Chen, Q Wang Langmuir 28 (4), 2028-2034, 2012 | 106 | 2012 |
Emodin reduces breast cancer lung metastasis by suppressing macrophage-induced breast cancer cell epithelial-mesenchymal transition and cancer stem cell formation Q Liu, J Hodge, J Wang, Y Wang, L Wang, UP Singh, Y Li, Y Yao, D Wang, ... Theranostics 10 (18), 8365, 2020 | 104 | 2020 |
HER2 overexpression triggers an IL1α proinflammatory circuit to drive tumorigenesis and promote chemotherapy resistance S Liu, JS Lee, C Jie, MH Park, Y Iwakura, Y Patel, M Soni, D Reisman, ... Cancer research 78 (8), 2040-2051, 2018 | 97 | 2018 |
MicroRNAs in pathogenesis of breast cancer: Implications in diagnosis and treatment NR Shah, H Chen World journal of clinical oncology 5 (2), 48, 2014 | 95 | 2014 |
HOXA5 acts directly downstream of retinoic acid receptor β and contributes to retinoic acid–induced apoptosis and growth inhibition H Chen, H Zhang, J Lee, X Liang, X Wu, T Zhu, P Lo, X Zhang, S Sukumar Cancer research 67 (17), 8007-8013, 2007 | 94 | 2007 |
Expansion of breast cancer stem cells with fibrous scaffolds S Feng, X Duan, PK Lo, S Liu, X Liu, H Chen, Q Wang Integrative Biology 5 (5), 768-777, 2013 | 93 | 2013 |
HIV infection of choroid plexus in AIDS and asymptomatic HIV-infected patients suggests that the choroid plexus may be a reservoir of productive infection CK Petito, H Chen, AR Mastri, J Torres-Munoz, B Roberts, C Wood Journal of neurovirology 5 (6), 670-677, 1999 | 86 | 1999 |
Hoxb7 inhibits transgenic HER-2/neu–induced mouse mammary tumor onset but promotes progression and lung metastasis H Chen, JS Lee, X Liang, H Zhang, T Zhu, Z Zhang, ME Taylor, C Zahnow, ... Cancer research 68 (10), 3637-3644, 2008 | 82 | 2008 |
Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination H Jo, PK Lo, Y Li, F Loison, S Green, J Wang, LE Silberstein, K Ye, ... Proceedings of the National Academy of Sciences 108 (16), 6486-6491, 2011 | 80 | 2011 |
A novel double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis regulates breast cancer cell proliferation and tumor growth Y Patel, N Shah, JS Lee, E Markoutsa, C Jie, S Liu, R Botbyl, D Reisman, ... Oncotarget 7 (14), 18295, 2016 | 78 | 2016 |
HOXB7 promotes malignant progression by activating the TGFβ signaling pathway S Liu, K Jin, Y Hui, J Fu, C Jie, S Feng, D Reisman, Q Wang, D Fan, ... Cancer research 75 (4), 709-719, 2015 | 77 | 2015 |