Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection DD Ho, AU Neumann, AS Perelson, W Chen, JM Leonard, M Markowitz Nature 373 (6510), 123-126, 1995 | 5777 | 1995 |
HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time AS Perelson, AU Neumann, M Markowitz, JM Leonard, DD Ho Science 271 (5255), 1582-1586, 1996 | 4773 | 1996 |
Self-nonself discrimination in a computer S Forrest, AS Perelson, L Allen, R Cherukuri Proceedings of 1994 IEEE computer society symposium on research in security …, 1994 | 3275 | 1994 |
Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-α therapy AU Neumann, NP Lam, H Dahari, DR Gretch, TE Wiley, TJ Layden, ... Science 282 (5386), 103-107, 1998 | 2819 | 1998 |
Decay characteristics of HIV-1-infected compartments during combination therapy AS Perelson, P Essunger, Y Cao, M Vesanen, A Hurley, K Saksela, ... Nature 387 (6629), 188-191, 1997 | 2382 | 1997 |
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection BF Keele, EE Giorgi, JF Salazar-Gonzalez, JM Decker, KT Pham, ... Proceedings of the National Academy of Sciences 105 (21), 7552-7557, 2008 | 2360 | 2008 |
The immune system, adaptation, and machine learning JD Farmer, NH Packard, AS Perelson Physica D: Nonlinear Phenomena 22 (1-3), 187-204, 1986 | 2350 | 1986 |
Mathematical analysis of HIV-1 dynamics in vivo AS Perelson, PW Nelson SIAM review 41 (1), 3-44, 1999 | 1994 | 1999 |
Dramatic Rise in Plasma Viremia after CD8+ T Cell Depletion in Simian Immunodeficiency Virus–infected Macaques X Jin, DE Bauer, SE Tuttleton, S Lewin, A Gettie, J Blanchard, CE Irwin, ... The Journal of experimental medicine 189 (6), 991-998, 1999 | 1827 | 1999 |
Modelling viral and immune system dynamics AS Perelson Nature reviews immunology 2 (1), 28-36, 2002 | 1257 | 2002 |
Dynamics of HIV infection of CD4+ T cells AS Perelson, DE Kirschner, R De Boer Mathematical biosciences 114 (1), 81-125, 1993 | 1232 | 1993 |
Nonlinear dynamics of immunogenic tumors: parameter estimation and global bifurcation analysis VA Kuznetsov, IA Makalkin, MA Taylor, AS Perelson Bulletin of mathematical biology 56 (2), 295-321, 1994 | 1177 | 1994 |
Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy L Zhang, B Ramratnam, K Tenner-Racz, Y He, M Vesanen, S Lewin, ... New England Journal of Medicine 340 (21), 1605-1613, 1999 | 998 | 1999 |
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection JF Salazar-Gonzalez, MG Salazar, BF Keele, GH Learn, EE Giorgi, H Li, ... Journal of Experimental Medicine 206 (6), 1273-1289, 2009 | 986 | 2009 |
Theoretical studies of clonal selection: minimal antibody repertoire size and reliability of self-non-self discrimination AS Perelson, GF Oster Journal of theoretical biology 81 (4), 645-670, 1979 | 894 | 1979 |
Kinetics of influenza A virus infection in humans P Baccam, C Beauchemin, CA Macken, FG Hayden, AS Perelson Journal of virology 80 (15), 7590-7599, 2006 | 889 | 2006 |
Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies … GD Tomaras, NL Yates, P Liu, L Qin, GG Fouda, LL Chavez, AC Decamp, ... Journal of virology 82 (24), 12449-12463, 2008 | 850 | 2008 |
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection N Goonetilleke, MKP Liu, JF Salazar-Gonzalez, G Ferrari, E Giorgi, ... Journal of experimental medicine 206 (6), 1253-1272, 2009 | 839 | 2009 |
Immunology for physicists AS Perelson, G Weisbuch Reviews of modern physics 69 (4), 1219, 1997 | 783 | 1997 |
Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues CV Fletcher, K Staskus, SW Wietgrefe, M Rothenberger, C Reilly, ... Proceedings of the National Academy of Sciences 111 (6), 2307-2312, 2014 | 782 | 2014 |