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Joanna Howson
Joanna Howson
Lecturer in Statistical Genomics, University of Cambridge
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Titolo
Citata da
Citata da
Anno
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
H Ueda, JMM Howson, L Esposito, J Heward, Snook, G Chamberlain, ...
Nature 423 (6939), 506-511, 2003
27162003
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
JA Todd, NM Walker, JD Cooper, DJ Smyth, K Downes, V Plagnol, ...
Nature genetics 39 (7), 857-864, 2007
1754*2007
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, ...
Nature genetics 50 (4), 524-537, 2018
14022018
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
E Evangelou, HR Warren, D Mosen-Ansorena, B Mifsud, R Pazoki, H Gao, ...
Nature genetics 50 (10), 1412-1425, 2018
12922018
The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ...
Nature 536 (7614), 41-47, 2016
12892016
Shared and distinct genetic variants in type 1 diabetes and celiac disease
DJ Smyth, V Plagnol, NM Walker, JD Cooper, K Downes, JHM Yang, ...
New England Journal of Medicine 359 (26), 2767-2777, 2008
9462008
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A
S Nejentsev, JMM Howson, NM Walker, J Szeszko, SF Field, HE Stevens, ...
Nature 450 (7171), 887, 2007
7152007
Rare and low-frequency coding variants alter human adult height
E Marouli, M Graff, C Medina-Gomez, KS Lo, AR Wood, TR Kjaer, RS Fine, ...
Nature 542 (7640), 186-190, 2017
6782017
Population structure, differential bias and genomic control in a large-scale, case-control association study
DG Clayton, NM Walker, DJ Smyth, R Pask, JD Cooper, LM Maier, ...
Nature genetics 37 (11), 1243-1246, 2005
6582005
Association analyses based on false discovery rate implicate new loci for coronary artery disease
CP Nelson, A Goel, AS Butterworth, S Kanoni, TR Webb, E Marouli, ...
Nature genetics 49 (9), 1385-1391, 2017
6572017
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus
D Smyth, JD Cooper, JE Collins, JM Heward, JA Franklyn, JMM Howson, ...
Diabetes 53 (11), 3020-3023, 2004
6562004
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
HR Warren, E Evangelou, CP Cabrera, H Gao, M Ren, B Mifsud, I Ntalla, ...
Nature genetics 49 (3), 403-415, 2017
6122017
Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease
P Zanoni, SA Khetarpal, DB Larach, WF Hancock-Cerutti, JS Millar, ...
Science 351 (6278), 1166-1171, 2016
5872016
Exome-wide association study of plasma lipids in> 300,000 individuals
DJ Liu, GM Peloso, H Yu, AS Butterworth, X Wang, A Mahajan, ...
Nature genetics 49 (12), 1758-1766, 2017
5672017
Bayesian refinement of association signals for 14 loci in 3 common diseases
JB Maller, G McVean, J Byrnes, D Vukcevic, K Palin, Z Su, JMM Howson, ...
Nature genetics 44 (12), 1294-1301, 2012
5332012
Association of LPA variants with risk of coronary disease and the implications for lipoprotein (a)-lowering therapies: a Mendelian randomization analysis
S Burgess, BA Ference, JR Staley, DF Freitag, AM Mason, SF Nielsen, ...
JAMA cardiology 3 (7), 619-627, 2018
5162018
The polygenic and monogenic basis of blood traits and diseases
D Vuckovic, EL Bao, P Akbari, CA Lareau, A Mousas, T Jiang, MH Chen, ...
Cell 182 (5), 1214-1231. e11, 2020
5152020
Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations
MH Chen, LM Raffield, A Mousas, S Sakaue, JE Huffman, A Moscati, ...
Cell 182 (5), 1198-1213. e14, 2020
4852020
A robust and efficient method for Mendelian randomization with hundreds of genetic variants
S Burgess, CN Foley, E Allara, JR Staley, JMM Howson
Nature communications 11 (1), 376, 2020
4622020
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
A Mahajan, J Wessel, SM Willems, W Zhao, NR Robertson, AY Chu, ...
Nature genetics 50 (4), 559-571, 2018
4432018
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