| Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study B Hellenkamp, S Schmid, O Doroshenko, O Opanasyuk, R Kühnemuth, ... Nature methods 15 (9), 669-676, 2018 | 468 | 2018 |
| Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions G Krainer, TJ Welsh, JA Joseph, P St George-Hyslop, AA Hyman, ... Nature Communications, 2021 | 366 | 2021 |
| Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions M Kar, F Dar, TJ Welsh, LT Vogel, R Kühnemuth, A Majumdar, G Krainer, ... Proceedings of the National Academy of Sciences 119 (28), e2202222119, 2022 | 174 | 2022 |
| Learning the molecular grammar of protein condensates from sequence determinants and embeddings KL Saar, AS Morgunov, R Qi, WE Arter, G Krainer, AA Lee, TPJ Knowles Proceedings of the National Academy of Sciences 118 (15), 2021 | 143 | 2021 |
| Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2 A Pechstein, J Bacetic, A Vahedi-Faridi, K Gromova, A Sundborger, ... Proceedings of the National Academy of Sciences 107 (9), 4206-4211, 2010 | 99 | 2010 |
| Surface electrostatics govern the emulsion stability of biomolecular condensates TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, ... Nano letters 22 (2), 612-621, 2022 | 98* | 2022 |
| Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses F Geiger, J Acker, G Papa, X Wang, WE Arter, KL Saar, NA Erkamp, R Qi, ... The EMBO Journal 40 (21), e107711, 2021 | 97 | 2021 |
| Conformational expansion of tau in condensates promotes irreversible aggregation J Wen, L Hong, G Krainer, QQ Yao, TPJ Knowles, S Wu, S Perrett Journal of the American Chemical Society 143 (33), 13056-13064, 2021 | 92 | 2021 |
| Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins G Agam, C Gebhardt, M Popara, R Mächtel, J Folz, B Ambrose, ... Nature methods 20 (4), 523-535, 2023 | 78 | 2023 |
| Structural stability of DNA origami nanostructures in the presence of chaotropic agents S Ramakrishnan, G Krainer, G Grundmeier, M Schlierf, A Keller Nanoscale 8 (19), 10398-10405, 2016 | 78 | 2016 |
| farFRET: extending the range in single-molecule FRET experiments beyond 10 nm G Krainer, A Hartmann, M Schlierf Nano letters 15 (9), 5826-5829, 2015 | 72 | 2015 |
| Interactions of α-synuclein oligomers with lipid membranes G Musteikytė, AK Jayaram, CK Xu, M Vendruscolo, G Krainer, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1863 (4), 183536, 2021 | 71 | 2021 |
| Single-experiment displacement assay for quantifying high-affinity binding by isothermal titration calorimetry G Krainer, S Keller Methods 76, 116-123, 2015 | 71 | 2015 |
| Aging can transform single-component protein condensates into multiphase architectures A Garaizar, JR Espinosa, JA Joseph, G Krainer, Y Shen, TPJ Knowles, ... Proceedings of the National Academy of Sciences 119 (26), e2119800119, 2022 | 69 | 2022 |
| Isothermal titration calorimetry for drug design: precision of the enthalpy and binding constant measurements and comparison of the instruments V Linkuvienė, G Krainer, WY Chen, D Matulis Analytical Biochemistry 515, 61-64, 2016 | 60 | 2016 |
| The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends MM Schneider, S Gautam, TW Herling, E Andrzejewska, G Krainer, ... Nature Communications 12 (1), 5999, 2021 | 59 | 2021 |
| Quantifying high-affinity binding of hydrophobic ligands by isothermal titration calorimetry G Krainer, J Broecker, C Vargas, J Fanghänel, S Keller Analytical chemistry 84 (24), 10715-10722, 2012 | 57 | 2012 |
| Biomolecular condensate phase diagrams with a combinatorial microdroplet platform WE Arter, R Qi, NA Erkamp, G Krainer, K Didi, TJ Welsh, J Acker, ... Nature Communications 13 (1), 7845, 2022 | 55* | 2022 |
| Tie-line analysis reveals interactions driving heteromolecular condensate formation D Qian, TJ Welsh, NA Erkamp, S Qamar, J Nixon-Abell, G Krainer, ... Physical Review X 12 (4), 041038, 2022 | 48 | 2022 |
| Microfluidic approaches for the analysis of protein–protein interactions in solution WE Arter, A Levin, G Krainer, TPJ Knowles Biophysical reviews 12 (2), 575-585, 2020 | 47 | 2020 |
Tuomas KnowlesProfessor of Physical Chemistry and Biophysics, University of CambridgeEmail verificata su cam.ac.uk