| Synergistic and tunable human gene activation by combinations of synthetic transcription factors P Perez-Pinera, DG Ousterout, JM Brunger, AM Farin, KA Glass, F Guilak, ... Nature methods 10 (3), 239, 2013 | 334 | 2013 |
| Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage JM Brunger, NPT Huynh, CM Guenther, P Perez-Pinera, FT Moutos, ... Proceedings of the National Academy of Sciences 111 (9), E798-E806, 2014 | 147 | 2014 |
| Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration AT Francisco, RJ Mancino, RD Bowles, JM Brunger, DM Tainter, YT Chen, ... Biomaterials 34 (30), 7381-7388, 2013 | 136 | 2013 |
| Chondrogenesis and Mineralization During In Vitro Culture of Human Mesenchymal Stem Cells on Three-Dimensional Woven Scaffolds CK Abrahamsson, F Yang, H Park, JM Brunger, PK Valonen, R Langer, ... Tissue Engineering Part A 16 (12), 3709-3718, 2010 | 122 | 2010 |
| Tissue-engineered cartilage with inducible and tunable immunomodulatory properties KA Glass, JM Link, JM Brunger, FT Moutos, CA Gersbach, F Guilak Biomaterials 35 (22), 5921-5931, 2014 | 121 | 2014 |
| CRISPR-based epigenome editing of cytokine receptors for the promotion of cell survival and tissue deposition in inflammatory environments N Farhang, JM Brunger, JD Stover, PI Thakore, B Lawrence, F Guilak, ... Tissue Engineering Part A 23 (15-16), 738-749, 2017 | 94 | 2017 |
| Genome engineering of stem cells for autonomously regulated, closed-loop delivery of biologic drugs JM Brunger, A Zutshi, VP Willard, CA Gersbach, F Guilak Stem cell reports 8 (5), 1202-1213, 2017 | 94 | 2017 |
| Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin H Kim, K Leng, J Park, AG Sorets, S Kim, A Shostak, RJ Embalabala, ... Nature communications 13 (1), 6581, 2022 | 85 | 2022 |
| CRISPR/Cas9 editing of murine induced pluripotent stem cells for engineering inflammation‐resistant tissues JM Brunger, A Zutshi, VP Willard, CA Gersbach, F Guilak Arthritis & Rheumatology 69 (5), 1111-1121, 2017 | 77 | 2017 |
| Genome engineering for personalized arthritis therapeutics SS Adkar, JM Brunger, VP Willard, CL Wu, CA Gersbach, F Guilak Trends in molecular medicine 23 (10), 917-931, 2017 | 62 | 2017 |
| Cortical tenting screw JM Brunger, JM Badura, JB Thomas US Patent 8,968,373, 2015 | 53 | 2015 |
| Long non-coding RNA GRASLND enhances chondrogenesis via suppression of interferon type II signaling pathway NPT Huynh, CC Gloss, J Lorentz, R Tang, JM Brunger, A McAlinden, ... eLife 9, e49558, 2020 | 42 | 2020 |
| Long non-coding RNA GRASLND enhances chondrogenesis via suppression of interferon type II signaling pathway NPT Huynh, CC Gloss, J Lorentz, R Tang, A McAlinden, B Zhang, ... bioRxiv, 650010, 2019 | 42 | 2019 |
| A synthetic gene circuit for self-regulating delivery of biologic drugs in engineered tissues L Pferdehirt, AK Ross, JM Brunger, F Guilak Tissue Engineering Part A 25 (9-10), 809-820, 2019 | 40 | 2019 |
| A Genome-engineered Bioartificial Implant for Autoregulated Anti-Cytokine Drug Delivery YR Choi, KH Collins, LE Springer, L Pferdehirt, AK Ross, CL Wu, ... bioRxiv, 535609, 2019 | 33 | 2019 |
| Synthetic development: learning to program multicellular self-organization S Toda, JM Brunger, WA Lim Current Opinion in Systems Biology, 2019 | 28 | 2019 |
| Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells BO Diekman, PI Thakore, SK O'Connor, VP Willard, JM Brunger, ... Tissue Engineering Part A 21 (7-8), 1261-1274, 2015 | 24 | 2015 |
| Genetic engineering of mesenchymal stem cells for differential matrix deposition on 3D woven scaffolds NPT Huynh, JM Brunger, CC Gloss, FT Moutos, CA Gersbach, F Guilak Tissue Engineering Part A 24 (19-20), 1531-1544, 2018 | 18 | 2018 |
| Instructional materials that control cellular activity through synthetic Notch receptors JC Lee, HJ Brien, BL Walton, ZM Eidman, S Toda, WA Lim, JM Brunger Biomaterials 297, 122099, 2023 | 17 | 2023 |
| Engineering approaches for RNA-based and cell-based osteoarthritis therapies CR DeJulius, BL Walton, JM Colazo, R d’Arcy, N Francini, JM Brunger, ... Nature Reviews Rheumatology 20 (2), 81-100, 2024 | 16 | 2024 |