Bradly Wouters

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Philippe LambinProfessor of Precision Medicine, Maastricht University & Scientist ULBEmail verificata su maastrichtuniversity.nl
Ludwig DuboisMaastricht UniversityEmail verificata su maastrichtuniversity.nl
kasper RouschopUniversitair Docent Radiotherapie, Universiteit van MaastrichtEmail verificata su maastrichtuniversity.nl
Constantinos KoumenisDepartment of Radiation Oncology, University of Pennsylvania School of MedicineEmail verificata su upenn.edu
Martin BrownRadiation oncology, Stanford UniversityEmail verificata su stanford.edu
Maud de Klerk-StarmansVieCuri Medical CenterEmail verificata su viecuri.nl
Soren M BentzenProfessor of Epidemiology and Public HealthEmail verificata su som.umaryland.edu
Dan CojocariAmgenEmail verificata su amgen.com
Paul C. BoutrosUniversity of California, Los AngelesEmail verificata su mednet.ucla.edu
Nahum SonenbergGilman Cheney Professor in BiochemistryEmail verificata su mcgill.ca
Adrian L HarrisProfessor of Medical Oncology, Oxford UniversityEmail verificata su oncology.ox.ac.uk
Hugo AertsDirector AI in Medicine (AIM) @ Harvard-MGB | Professor @ MaastrichtUEmail verificata su dfci.harvard.edu
Francesca BuffaProfessor Computing Sciences @Bocconi University - CBIG Lab @Oxford University - AI Lab @IFOM MilanEmail verificata su unibocconi.it
Andre DekkerProfessor of Clinical Data Science, MAASTRO Clinic, Maastricht University, GROW, Maastricht UMC+Email verificata su maastro.nl
Niels BasslerAarhus UniversityEmail verificata su clin.au.dk
Chris EveloHead Department of Bioinformatics - BiGCaT, Maastricht University ORCID:0000-0002-5301-3142Email verificata su maastrichtuniversity.nl
Nicholas Denkoprofessor of radiation oncology ohio state uiversityEmail verificata su osumc.edu
Randall S. JohnsonUniversity of Cambridge and Karolinska Institutet and UC San DiegoEmail verificata su cam.ac.uk
Pierre ThibaultProfessor, Universite de MontrealEmail verificata su umontreal.ca
Tiffany N. SeagrovesProfessor of Medicine, Section of Hematology & Medical Oncology, Tulane School of MedicineEmail verificata su tulane.edu

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Bradly Wouters

Princess Margaret Cancer Centre, University Health Network, University of Toronto

Email verificata su uhn.ca

Hypoxia UPR epigenetics radiobiology radiation oncology


Titolo Ordina per citazioni Ordina per anno Ordina per titolo	Citata da Citata da	Anno
Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ... Autophagy 8 (4), 445-544, 2012	13739*	2012
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study F Pagès, B Mlecnik, F Marliot, G Bindea, FS Ou, C Bifulco, A Lugli, ... The Lancet 391 (10135), 2128-2139, 2018	1950	2018
Towards the introduction of the ‘Immunoscore’in the classification of malignant tumours J Galon, B Mlecnik, G Bindea, HK Angell, A Berger, C Lagorce, A Lugli, ... The Journal of pathology 232 (2), 199-209, 2014	1552	2014
Hypoxia signalling through mTOR and the unfolded protein response in cancer BG Wouters, M Koritzinsky Nature Reviews Cancer 8 (11), 851-864, 2008	1067	2008
Apoptosis, p53, and tumor cell sensitivity to anticancer agents JM Brown, BG Wouters Cancer research 59 (7), 1391-1399, 1999	994	1999
Cancer classification using the Immunoscore: a worldwide task force J Galon, F Pagès, FM Marincola, HK Angell, M Thurin, A Lugli, I Zlobec, ... Journal of translational medicine 10, 1-10, 2012	976	2012
ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth M Bi, C Naczki, M Koritzinsky, D Fels, J Blais, N Hu, H Harding, I Novoa, ... The EMBO journal 24 (19), 3470-3481, 2005	929	2005
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5 KMA Rouschop, T van den Beucken, L Dubois, H Niessen, J Bussink, ... The Journal of clinical investigation 120 (1), 127-141, 2010	918	2010
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α C Koumenis, C Naczki, M Koritzinsky, S Rastani, A Diehl, N Sonenberg, ... Molecular and cellular biology 22 (21), 7405-7416, 2002	869	2002
Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells TN Seagroves, HE Ryan, H Lu, BG Wouters, M Knapp, P Thibault, ... Molecular and cellular biology, 2001	787	2001
Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and-Independent Mechanisms and Contributes to Drug Resistance JT Erler, CJ Cawthorne, KJ Williams, M Koritzinsky, BG Wouters, C Wilson, ... Molecular and Cellular Biology 24 (7), 2875-2889, 2004	536	2004
Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis JC Sluimer, JM Gasc, JL van Wanroij, N Kisters, M Groeneweg, ... Journal of the American College of Cardiology 51 (13), 1258-1265, 2008	535	2008
Activating transcription factor 4 is translationally regulated by hypoxic stress JD Blais, V Filipenko, M Bi, HP Harding, D Ron, C Koumenis, BG Wouters, ... Molecular and cellular biology 24 (17), 7469-7482, 2004	522	2004
Cells at intermediate oxygen levels can be more important than the" hypoxic fraction" in determining tumor response to fractionated radiotherapy BG Wouters, JM Brown Radiation research 147 (5), 541-550, 1997	432	1997
Time between the first day of chemotherapy and the last day of chest radiation is the most important predictor of survival in limited-disease small-cell lung cancer D De Ruysscher, M Pijls-Johannesma, SM Bentzen, A Minken, ... Journal of Clinical Oncology 24 (7), 1057-1063, 2006	427	2006
Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control M Koritzinsky, MG Magagnin, T van den Beucken, R Seigneuric, ... The EMBO journal 25 (5), 1114-1125, 2006	414	2006
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress P van Galen, A Kreso, N Mbong, DG Kent, T Fitzmaurice, JE Chambers, ... Nature 510 (7504), 268-272, 2014	376	2014
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance N Chan, M Koritzinsky, H Zhao, R Bindra, PM Glazer, S Powell, ... Cancer research 68 (2), 605-614, 2008	363	2008
Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response VE Zannella, A Dal Pra, H Muaddi, TD McKee, S Stapleton, J Sykes, ... Clinical cancer research 19 (24), 6741-6750, 2013	327	2013
“Translating” tumor hypoxia: Unfolded protein response (UPR)–dependent and UPR-independent pathways C Koumenis, BG Wouters Molecular Cancer Research 4 (7), 423-436, 2006	288	2006

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