Sphingosine-1-phosphate: an enigmatic signalling lipid S Spiegel, S Milstien Nature reviews Molecular cell biology 4 (5), 397-407, 2003 | 2525 | 2003 |
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate O Cuvillier, G Pirianov, B Kleuser, PG Vanek, OA Coso, JS Gutkind, ... Nature 381 (6585), 800-803, 1996 | 1928 | 1996 |
Edg-1, the G protein–coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation Y Liu, R Wada, T Yamashita, Y Mi, CX Deng, JP Hobson, HM Rosenfeldt, ... The Journal of clinical investigation 106 (8), 951-961, 2000 | 1402 | 2000 |
Sphingolipid metabolites in inflammatory disease M Maceyka, S Spiegel Nature 510 (7503), 58-67, 2014 | 1243 | 2014 |
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1 MJ Lee, JR Van Brocklyn, S Thangada, CH Liu, AR Hand, R Menzeleev, ... Science 279 (5356), 1552-1555, 1998 | 1221 | 1998 |
Sphingosine-1-phosphate signaling and its role in disease M Maceyka, KB Harikumar, S Milstien, S Spiegel Trends in cell biology 22 (1), 50-60, 2012 | 1168 | 2012 |
Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate NC Hait, J Allegood, M Maceyka, GM Strub, KB Harikumar, SK Singh, ... Science 325 (5945), 1254-1257, 2009 | 1138 | 2009 |
Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens A Olivera, S Spiegel Nature 365 (6446), 557-560, 1993 | 1128 | 1993 |
Essential role for sphingosine kinases in neural and vascular development K Mizugishi, T Yamashita, A Olivera, GF Miller, S Spiegel, RL Proia Molecular and cellular biology 25 (24), 11113-11121, 2005 | 916 | 2005 |
Sphingolipid metabolism and cell growth regulation S Spiegel, AH Merrill Jr The FASEB Journal 10 (12), 1388-1397, 1996 | 896 | 1996 |
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2 SE Alvarez, KB Harikumar, NC Hait, J Allegood, GM Strub, EY Kim, ... Nature 465 (7301), 1084-1088, 2010 | 893 | 2010 |
The outs and the ins of sphingosine-1-phosphate in immunity S Spiegel, S Milstien Nature Reviews Immunology 11 (6), 403-415, 2011 | 892 | 2011 |
“Inside-out” signaling of sphingosine-1-phosphate: therapeutic targets K Takabe, SW Paugh, S Milstien, S Spiegel Pharmacological reviews 60 (2), 181-195, 2008 | 868 | 2008 |
Sphingolipids—the enigmatic lipid class: biochemistry, physiology, and pathophysiology AH Merrill Jr, EM Schmelz, DL Dillehay, S Spiegel, JA Shayman, ... Toxicology and applied pharmacology 142 (1), 208-225, 1997 | 842 | 1997 |
Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform H Liu, M Sugiura, VE Nava, LC Edsall, K Kono, S Poulton, S Milstien, ... Journal of Biological Chemistry 275 (26), 19513-19520, 2000 | 832 | 2000 |
Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. H Zhang, NN Desai, A Olivera, T Seki, G Brooker, S Spiegel The Journal of cell biology 114 (1), 155-167, 1991 | 820 | 1991 |
Sphingosine 1-phosphate, a key cell signaling molecule S Spiegel, S Milstien Journal of Biological Chemistry 277 (29), 25851-25854, 2002 | 770 | 2002 |
SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism M Maceyka, H Sankala, NC Hait, H Le Stunff, H Liu, R Toman, C Collier, ... Journal of Biological Chemistry 280 (44), 37118-37129, 2005 | 769 | 2005 |
Sphingosine kinase, sphingosine-1-phosphate, and apoptosis M Maceyka, SG Payne, S Milstien, S Spiegel Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2002 | 723 | 2002 |
Molecular cloning and functional characterization of murine sphingosine kinase T Kohama, A Olivera, L Edsall, MM Nagiec, R Dickson, S Spiegel Journal of Biological Chemistry 273 (37), 23722-23728, 1998 | 714 | 1998 |