Rational HIV immunogen design to target specific germline B cell receptors J Jardine, JP Julien, S Menis, T Ota, O Kalyuzhniy, A McGuire, D Sok, ... Science 340 (6133), 711-716, 2013 | 830 | 2013 |
Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling AL Gavin, K Hoebe, B Duong, T Ota, C Martin, B Beutler, D Nemazee Science 314 (5807), 1936-1938, 2006 | 711 | 2006 |
PI3K-mediated negative feedback regulation of IL-12 production in DCs T Fukao, M Tanabe, Y Terauchi, T Ota, S Matsuda, T Asano, T Kadowaki, ... Nature immunology 3 (9), 875-881, 2002 | 667 | 2002 |
Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen JG Jardine, T Ota, D Sok, M Pauthner, DW Kulp, O Kalyuzhniy, PD Skog, ... Science 349 (6244), 156-161, 2015 | 448 | 2015 |
Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3 K Tsunoda, T Ota, M Aoki, T Yamada, T Nagai, T Nakagawa, S Koyasu, ... The Journal of Immunology 170 (4), 2170-2178, 2003 | 361 | 2003 |
Precursor frequency and affinity determine B cell competitive fitness in germinal centers, tested with germline-targeting HIV vaccine immunogens RK Abbott, JH Lee, S Menis, P Skog, M Rossi, T Ota, DW Kulp, D Bhullar, ... Immunity 48 (1), 133-146. e6, 2018 | 320 | 2018 |
Critical role of IL-15–IL-15R for antigen-presenting cell functions in the innate immune response T Ohteki, K Suzue, C Maki, T Ota, S Koyasu Nature immunology 2 (12), 1138-1143, 2001 | 246 | 2001 |
Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice T Fukao, T Yamada, M Tanabe, Y Terauchi, T Ota, T Takayama, T Asano, ... Nature immunology 3 (3), 295-304, 2002 | 243 | 2002 |
Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo BH Duong, H Tian, T Ota, G Completo, S Han, JL Vela, M Ota, M Kubitz, ... Journal of Experimental Medicine 207 (1), 173-187, 2010 | 188 | 2010 |
Regulation of the B cell receptor repertoire and self-reactivity by BAFF M Ota, BH Duong, A Torkamani, CM Doyle, AL Gavin, T Ota, D Nemazee The Journal of Immunology 185 (7), 4128-4136, 2010 | 128 | 2010 |
Enhanced plasma ghrelin levels in rats with streptozotocin‐induced diabetes T Masaoka, H Suzuki, H Hosoda, T Ota, Y Minegishi, H Nagata, ... FEBS letters 541 (1-3), 64-68, 2003 | 124 | 2003 |
Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci K Beck, MM Peak, T Ota, D Nemazee, C Murre Journal of Experimental Medicine 206 (10), 2271-2284, 2009 | 122 | 2009 |
Helicobacter pylori infection modifies gastric and plasma ghrelin dynamics in Mongolian gerbils H Suzuki, T Masaoka, H Hosoda, T Ota, Y Minegishi, S Nomura, ... Gut 53 (2), 187-194, 2004 | 117 | 2004 |
Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10 C Doyle-Cooper, KE Hudson, AB Cooper, T Ota, P Skog, PE Dawson, ... The Journal of Immunology 191 (6), 3186-3191, 2013 | 115 | 2013 |
Pathogenic autoantibody production requires loss of tolerance against desmoglein 3 in both T and B cells in experimental pemphigus vulgaris K Tsunoda, T Ota, H Suzuki, M Ohyama, T Nagai, T Nishikawa, M Amagai, ... European journal of immunology 32 (3), 627-633, 2002 | 102 | 2002 |
IgG binds to desmoglein 3 in desmosomes and causes a desmosomal split without keratin retraction in a pemphigus mouse model A Shimizu, A Ishiko, T Ota, K Tsunoda, M Amagai, T Nishikawa Journal of Investigative Dermatology 122 (5), 1145-1153, 2004 | 96 | 2004 |
Genetic identification and detection of human pathogenic Rhizopus species, a major mucormycosis agent, by multiplex PCR based on internal transcribed spacer region of rRNA gene K Nagao, T Ota, A Tanikawa, Y Takae, T Mori, S Udagawa, T Nishikawa Journal of dermatological science 39 (1), 23-31, 2005 | 94 | 2005 |
Down‐regulation of a morphogen (sonic hedgehog) gradient in the gastric epithelium of Helicobacter pylori‐infected Mongolian gerbils H Suzuki, Y Minegishi, Y Nomoto, T Ota, T Masaoka, GR van den Brink, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2005 | 89 | 2005 |
Covalent linkage of HIV-1 trimers to synthetic liposomes elicits improved B cell and antibody responses S Bale, G Goebrecht, A Stano, R Wilson, T Ota, K Tran, J Ingale, MB Zwick, ... Journal of virology 91 (16), 10.1128/jvi. 00443-17, 2017 | 84 | 2017 |
Skewed primary Igκ repertoire and V–J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing M Aoki-Ota, A Torkamani, T Ota, N Schork, D Nemazee The Journal of Immunology 188 (5), 2305-2315, 2012 | 74 | 2012 |