| The interplay of glutathione-related processes in antioxidant defense NHP Cnubben, IMCM Rietjens, H Wortelboer, J van Zanden, ... Environmental toxicology and pharmacology 10 (4), 141-152, 2001 | 545 | 2001 |
| The impact of food bioactives on health: in vitro and ex vivo models K Verhoeckx, P Cotter, I López-Expósito, C Kleiveland, T Lea, A Mackie, ... Springer Nature, 2015 | 404 | 2015 |
| Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2 JJ van Zanden, HM Wortelboer, S Bijlsma, A Punt, M Usta, ... Biochemical pharmacology 69 (4), 699-708, 2005 | 229 | 2005 |
| Structure elucidation of acid reaction products of indole-3-carbinol: detection in vivo and enzyme induction in vitro CA De Kruif, JW Marsman, JC Venekamp, HE Falke, J Noordhoek, ... Chemico-biological interactions 80 (3), 303-315, 1991 | 224 | 1991 |
| Variability in P-glycoprotein inhibitory potency (IC50) using various in vitro experimental systems: implications for universal digoxin drug-drug interaction risk assessment … J Bentz, MP O’Connor, D Bednarczyk, JA Coleman, C Lee, J Palm, ... Drug metabolism and disposition 41 (7), 1347-1366, 2013 | 178 | 2013 |
| The isoenzyme pattern of cytochrome P450 in rat hepatocytes in primary culture, comparing different enzyme activities in microsomal incubations and in intact monolayers HM Wortelboer, CA De Kruif, AAJ Van Iersel, HE Falke, J Noordhoek, ... Biochemical pharmacology 40 (11), 2525-2534, 1990 | 169 | 1990 |
| Docosahexaenoic acid and eicosapentaenoic acid are converted by 3T3-L1 adipocytes to N-acyl ethanolamines with anti-inflammatory properties MGJ Balvers, KCM Verhoeckx, P Plastina, HM Wortelboer, J Meijerink, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010 | 165 | 2010 |
| Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells JJ van Zanden, L Geraets, HM Wortelboer, PJ van Bladeren, ... Biochemical pharmacology 67 (8), 1607-1617, 2004 | 165 | 2004 |
| Interplay between MRP inhibition and metabolism of MRP inhibitors: the case of curcumin HM Wortelboer, M Usta, AE van der Velde, MG Boersma, B Spenkelink, ... Chemical research in toxicology 16 (12), 1642-1651, 2003 | 147 | 2003 |
| Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures: the effects of model inducers on apoproteins and biotransformation activities HM Wortelboer, CA De Kruif, AAJ Van Iersel, HE Falke, J Noordhoek, ... Biochemical pharmacology 42 (2), 381-390, 1991 | 134 | 1991 |
| Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues MGJ Balvers, KCM Verhoeckx, S Bijlsma, CM Rubingh, J Meijerink, ... Metabolomics 8, 1130-1147, 2012 | 130 | 2012 |
| A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices J Westerhout, E van de Steeg, D Grossouw, EE Zeijdner, CAM Krul, ... European Journal of Pharmaceutical Sciences 63, 167-177, 2014 | 127 | 2014 |
| Variability in mass spectrometry-based quantification of clinically relevant drug transporters and drug metabolizing enzymes C Wegler, FZ Gaugaz, TB Andersson, JR Wiśniewski, D Busch, C Gröer, ... Molecular pharmaceutics 14 (9), 3142-3151, 2017 | 114 | 2017 |
| Effects of indole-3-carbinol on biotransformation enzymes in the rat: in vivo changes in liver and small intestinal mucosa in comparison with primary hepatocyte cultures HM Wortelboer, ECM Van Der Linden, CA De Kruif, J Noordhoek, ... Food and chemical toxicology 30 (7), 589-599, 1992 | 103 | 1992 |
| The effect of quercetin phase II metabolism on its MRP1 and MRP2 inhibiting potential JJ van Zanden, H van der Woude, J Vaessen, M Usta, HM Wortelboer, ... Biochemical pharmacology 74 (2), 345-351, 2007 | 100 | 2007 |
| Regional expression levels of drug transporters and metabolizing enzymes along the pig and human intestinal tract and comparison with Caco-2 cells SFC Vaessen, MMH van Lipzig, RHH Pieters, CAM Krul, HM Wortelboer, ... Drug metabolism and disposition 45 (4), 353-360, 2017 | 95 | 2017 |
| Acid reaction products of indole-3-carbinol and their effects on cytochrome P450 and phase II enzymes in rat and monkey hepatocytes HM Wortelboer, CA De Kruif, AAJ Van Iersel, HE Falke, J Noordhoek, ... Biochemical pharmacology 43 (7), 1439-1447, 1992 | 95 | 1992 |
| Interlaboratory comparison of microsomal ethoxyresorufin and pentoxyresorufin O-dealkylation determinations: standardization of assay conditions A Rutten, HE Falke, JF Catsburg, HM Wortelboer, BJ Blaauboer, L Doorn, ... Archives of toxicology 66, 237-244, 1992 | 86 | 1992 |
| Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of α, β-unsaturated carbonyl compounds HM Wortelboer, M Usta, JJ van Zanden, PJ van Bladeren, IMCM Rietjens, ... Biochemical pharmacology 69 (12), 1879-1890, 2005 | 84 | 2005 |
| Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4 AAK El-Sheikh, R Greupink, HM Wortelboer, JJMW Van Den Heuvel, ... Translational research 162 (6), 398-409, 2013 | 80 | 2013 |
Ben van OmmenPrincipal Scientist, TNOEmail verificata su tno.nl