The structure of Pyrococcus furiosus glutamate dehydrogenase reveals a key role for ion-pair networks in maintaining enzyme stability at extreme temperatures KSP Yip, TJ Stillman, KL Britton, PJ Artymiuk, PJ Baker, SE Sedelnikova, ... Structure 3 (11), 1147-1158, 1995 | 566 | 1995 |
The production of superoxide anion radicals in the reaction of reduced flavins and flavoproteins with molecular oxygen V Massey, S Strickland, SG Mayhew, LG Howell, PC Engel, RG Matthews, ... Biochemical and biophysical research communications 36 (6), 891-897, 1969 | 554 | 1969 |
Causes and elimination of erratic blanks in enzymatic metabolite assays involving the use of NAD+ in alkaline hydrazine buffers: improved conditions for the assay of L … PC Engel, JB Jones Analytical biochemistry 88 (2), 475-484, 1978 | 283 | 1978 |
Subunit assembly and active site location in the structure of glutamate dehydrogenase PJ Baker, KL Britton, PC Engel, GW Farrants, KS Lilley, DW Rice, ... Proteins: Structure, Function, and Bioinformatics 12 (1), 75-86, 1992 | 282 | 1992 |
Medium-chain acyl-CoA dehydrogenase (MCAD) mutations identified by MS/MS-based prospective screening of newborns differ from those observed in patients with clinical symptoms … BS Andresen, SF Dobrowolski, L O'Reilly, J Muenzer, SE McCandless, ... The American Journal of Human Genetics 68 (6), 1408-1418, 2001 | 278 | 2001 |
Enzyme kinetics: the steady-state approach PC Engel Springer, 2013 | 203 | 2013 |
Protein thermostability in extremophiles R Scandurra, V Consalvi, R Chiaraluce, L Politi, PC Engel Biochimie 80 (11), 933-941, 1998 | 194 | 1998 |
Kinetic studies of glutamate dehydrogenase with glutamate and norvaline as substrates. Coenzyme activation and negative homotropic interactions in allosteric enzymes PC Engel, K Dalziel Biochemical Journal 115 (4), 621-631, 1969 | 194 | 1969 |
Insights into Thermal Stability from a Comparison of the Glutamate Dehydrogenases from Pyrococcus furiosus and Thermococcus litoralis KL Britton, PJ Baker, KMM Borges, PC Engel, A Pasquo, DW Rice, ... European journal of biochemistry 229 (3), 688-695, 1995 | 163 | 1995 |
Defects of metabolism of fatty acids in the sudden infant death syndrome. AJ Howat, MJ Bennett, S Variend, L Shaw, PC Engel Br Med J (Clin Res Ed) 290 (6484), 1771-1773, 1985 | 156 | 1985 |
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa A Aherne, A Kennan, PF Kenna, N McNally, DG Lloyd, IL Alberts, ... Human molecular genetics 13 (6), 641-650, 2004 | 125 | 2004 |
The equilibrium constants of the glutamate dehydrogenase systems PC Engel, K Dalziel Biochemical Journal 105 (2), 691-695, 1967 | 118 | 1967 |
Antagonistic homotropic interactions as a possible explanation of coenzyme activation of glutamate dehydrogenase K Dalziel, PC Engel FEBS letters 1 (5), 349-352, 1968 | 116 | 1968 |
Guanylyl cyclases with the topology of mammalian adenylyl cyclases and an N-terminal P-type ATPase-like domain in Paramecium, Tetrahymena and Plasmodium JU Linder, P Engel, A Reimer, T Krüger, H Plattner, A Schultz, JE Schultz The EMBO journal 18 (15), 4222-4232, 1999 | 112 | 1999 |
The glutamate dehydrogenase gene of Clotridium symbiosum Cloning by polymerase chain reaction, sequence analysis and over‐expression in Escherichia coli JK Teller, RJ Smith, MJ McPHERSON, PC Engel, JR Guest European Journal of Biochemistry 206 (1), 151-159, 1992 | 110 | 1992 |
Kinetic studies of glutamate dehydrogenase. The reductive amination of 2-oxoglutarate PC Engel, K Dalziel Biochemical Journal 118 (3), 409-419, 1970 | 102 | 1970 |
The purification and properties of butyryl-coenzyme A dehydrogenase from Peptostreptococcus elsdenii PC Engel, V Massey Biochemical Journal 125 (3), 879-887, 1971 | 97 | 1971 |
Green butyryl-coenzyme A dehydrogenase. An enzyme–acyl-coenzyme A complex PC Engel, V Massey Biochemical Journal 125 (3), 889-902, 1971 | 95 | 1971 |
Evidence that the greening ligand in native butyryl-CoA dehydrogenase is a CoA persulfide. G Williamson, PC Engel, JP Mizzer, C Thorpe, V Massey Journal of Biological Chemistry 257 (8), 4314-4320, 1982 | 92 | 1982 |
Specific diagnosis of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in dried blood spots by a polymerase chain reaction (PCR) assay detecting a point-mutation (G985) in … N Gregersen, AIF Blakemore, V Winter, B Andresen, S Kølvraa, L Bolund, ... Clinica chimica acta 203 (1), 23-34, 1991 | 90 | 1991 |