| BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis L Scorrano, SA Oakes, JT Opferman, EH Cheng, MD Sorcinelli, T Pozzan, ... Science 300 (5616), 135-139, 2003 | 1799 | 2003 |
| Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1 JT Opferman, A Letai, C Beard, MD Sorcinelli, CC Ong, SJ Korsmeyer Nature 426 (6967), 671-676, 2003 | 1034 | 2003 |
| NIX is required for programmed mitochondrial clearance during reticulocyte maturation RL Schweers, J Zhang, MS Randall, MR Loyd, W Li, FC Dorsey, M Kundu, ... Proceedings of the National Academy of Sciences 104 (49), 19500-19505, 2007 | 976 | 2007 |
| Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells JT Opferman, H Iwasaki, CC Ong, H Suh, S Mizuno, K Akashi, ... Science 307 (5712), 1101-1104, 2005 | 740 | 2005 |
| Apoptosis in the development and maintenance of the immune system JT Opferman, SJ Korsmeyer Nature immunology 4 (5), 410-415, 2003 | 740 | 2003 |
| Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance G Wei, D Twomey, J Lamb, K Schlis, J Agarwal, RW Stam, JT Opferman, ... Cancer cell 10 (4), 331-342, 2006 | 600 | 2006 |
| Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum SA Oakes, L Scorrano, JT Opferman, MC Bassik, M Nishino, T Pozzan, ... Proceedings of the National Academy of Sciences 102 (1), 105-110, 2005 | 539 | 2005 |
| Linear differentiation of cytotoxic effectors into memory T lymphocytes JT Opferman, BT Ober, PG Ashton-Rickardt Science 283 (5408), 1745-1748, 1999 | 503 | 1999 |
| Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration RM Perciavalle, DP Stewart, B Koss, J Lynch, S Milasta, M Bathina, ... Nature cell biology 14 (6), 575-583, 2012 | 478 | 2012 |
| Anti-apoptotic BCL-2 family members in development JT Opferman, A Kothari Cell Death & Differentiation 25 (1), 37-45, 2018 | 363 | 2018 |
| GM1-ganglioside accumulation at the mitochondria-associated ER membranes links ER stress to Ca2+-dependent mitochondrial apoptosis R Sano, I Annunziata, A Patterson, S Moshiach, E Gomero, J Opferman, ... Molecular cell 36 (3), 500-511, 2009 | 328 | 2009 |
| LC3-associated phagocytosis in myeloid cells promotes tumor immune tolerance LD Cunha, M Yang, R Carter, C Guy, L Harris, JC Crawford, G Quarato, ... Cell 175 (2), 429-441. e16, 2018 | 299 | 2018 |
| Deletion of MCL-1 causes lethal cardiac failure and mitochondrial dysfunction X Wang, M Bathina, J Lynch, B Koss, C Calabrese, S Frase, JD Schuetz, ... Genes & development 27 (12), 1351-1364, 2013 | 286 | 2013 |
| Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons JR Chao, E Parganas, K Boyd, CY Hong, JT Opferman, JN Ihle Nature 452 (7183), 98-102, 2008 | 277 | 2008 |
| Delving deeper: MCL-1's contributions to normal and cancer biology RM Perciavalle, JT Opferman Trends in cell biology 23 (1), 22-29, 2013 | 273 | 2013 |
| Multiple signaling pathways promote B lymphocyte stimulator–dependent B-cell growth and survival RT Woodland, CJ Fox, MR Schmidt, PS Hammerman, JT Opferman, ... Blood, The Journal of the American Society of Hematology 111 (2), 750-760, 2008 | 255 | 2008 |
| Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage N Arbour, JL Vanderluit, JN Le Grand, A Jahani-Asl, VA Ruzhynsky, ... Journal of Neuroscience 28 (24), 6068-6078, 2008 | 238 | 2008 |
| Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules MA Markiewicz, C Girao, JT Opferman, J Sun, Q Hu, AA Agulnik, ... Proceedings of the National Academy of Sciences 95 (6), 3065-3070, 1998 | 232 | 1998 |
| Venetoclax and navitoclax in combination with chemotherapy in patients with relapsed or refractory acute lymphoblastic leukemia and lymphoblastic lymphoma VA Pullarkat, NJ Lacayo, E Jabbour, JE Rubnitz, A Bajel, TW Laetsch, ... Cancer discovery 11 (6), 1440-1453, 2021 | 216 | 2021 |
| MCL‐1 is a stress sensor that regulates autophagy in a developmentally regulated manner M Germain, AP Nguyen, JN Le Grand, N Arbour, JL Vanderluit, DS Park, ... The EMBO journal 30 (2), 395-407, 2011 | 210 | 2011 |