Microbiota-derived metabolite promotes HDAC3 activity in the gut S Wu, S Hashimoto-Hill, V Woo, EM Eshleman, J Whitt, L Engleman, ... Nature 586 (7827), 108-112, 2020 | 177 | 2020 |
Varicella zoster virus latency E Eshleman, A Shahzad, RJ Cohrs Future virology 6 (3), 341-355, 2011 | 82 | 2011 |
Commensal segmented filamentous bacteria-derived retinoic acid primes host defense to intestinal infection V Woo, EM Eshleman, S Hashimoto-Hill, J Whitt, S Wu, L Engleman, ... Cell host & microbe 29 (12), 1744-1756. e5, 2021 | 62 | 2021 |
Type I interferons in bacterial infections: taming of myeloid cells and possible implications for autoimmunity EM Eshleman, LL Lenz Frontiers in immunology 5, 431, 2014 | 61 | 2014 |
Type I IFNs downregulate myeloid cell IFN-γ receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription SJ Kearney, C Delgado, EM Eshleman, KK Hill, BP O’Connor, LL Lenz The Journal of Immunology 191 (6), 3384-3392, 2013 | 56 | 2013 |
Histone deacetylase inhibition by gut microbe-generated short-chain fatty acids entrains intestinal epithelial circadian rhythms JA Fawad, DH Luzader, GF Hanson, TJ Moutinho Jr, CA McKinney, ... Gastroenterology 163 (5), 1377-1390. e11, 2022 | 55 | 2022 |
Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity EM Eshleman, TY Shao, V Woo, T Rice, L Engleman, BJ Didriksen, ... The Journal of clinical investigation 133 (4), 2023 | 33 | 2023 |
Down regulation of macrophage IFNGR1 exacerbates systemic L. monocytogenes infection EM Eshleman, C Delgado, SJ Kearney, RS Friedman, LL Lenz PLoS Pathogens 13 (5), e1006388, 2017 | 32 | 2017 |
Microbiota inhibit epithelial pathogen adherence by epigenetically regulating C-type lectin expression V Woo, EM Eshleman, T Rice, J Whitt, BA Vallance, T Alenghat Frontiers in Immunology 10, 928, 2019 | 27 | 2019 |
Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity EM Eshleman, T Rice, C Potter, A Waddell, S Hashimoto-Hill, V Woo, ... Immunity 57 (2), 319-332. e6, 2024 | 26 | 2024 |
Human anti-varicella-zoster virus (VZV) recombinant monoclonal antibody produced after Zostavax immunization recognizes the gH/gL complex and neutralizes VZV infection M Birlea, GP Owens, EM Eshleman, A Ritchie, I Traktinskiy, N Bos, S Seitz, ... Journal of Virology 87 (1), 415-421, 2013 | 24 | 2013 |
Epithelial sensing of microbiota-derived signals EM Eshleman, T Alenghat Genes & Immunity 22 (5), 237-246, 2021 | 17 | 2021 |
IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation GR Overcast, HE Meibers, EM Eshleman, I Saha, L Waggoner, KN Patel, ... Journal of Experimental Medicine 220 (6), e20212523, 2023 | 10 | 2023 |
Ligand-induced IFNGR1 down-regulation calibrates myeloid cell IFNγ responsiveness WJ Crisler, EM Eshleman, LL Lenz Life Science Alliance 2 (5), 2019 | 7 | 2019 |
Myeloid cell responsiveness to interferon-gamma is sufficient for initial resistance to Listeria monocytogenes EM Eshleman, N Bortell, DS McDermott, WJ Crisler, LL Lenz Current research in immunology 1, 1-9, 2020 | 4 | 2020 |
Epithelial cell intrinsic IL-1R signaling regulates intestinal homeostasis and inflammation G Overcast, E Eshleman, T Alenghat, C Pasare The Journal of Immunology 204 (1_Supplement), 235.6-235.6, 2020 | 3 | 2020 |
Type I interferons down regulate myeloid cell IFNGR by inducing recruitment of an Egr3/Nab1 complex that silences ifngr1 transcription SJ Kearney, C Delgado, EM Eshleman, KK Hill, BP O'Connor, LL Lenz Journal of immunology (Baltimore, Md.: 1950) 191 (6), 3384, 2013 | 3 | 2013 |
Epithelial regulation of microbiota-immune cell dynamics BJ Didriksen, EM Eshleman, T Alenghat Mucosal Immunology, 2024 | 2 | 2024 |
Microbiota dampen type 2 immunity by epigenetically restricting tuft cell differentiation EM Eshleman, T Rice, C Potter, V Woo, S Field, S Hashimoto-Hill, ... The Journal of Immunology 210 (1_Supplement), 150.08-150.08, 2023 | 2 | 2023 |
Microbiota‐derived butyrate dampens linaclotide stimulation of the guanylate cyclase C pathway in patient‐derived colonoids A Velez Lopez, A Waddell, S Antonacci, D Castillo, N Santucci, ... Neurogastroenterology & Motility 35 (12), e14681, 2023 | 1 | 2023 |