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Emily M. Eshleman
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Microbiota-derived metabolite promotes HDAC3 activity in the gut
S Wu, S Hashimoto-Hill, V Woo, EM Eshleman, J Whitt, L Engleman, ...
Nature 586 (7827), 108-112, 2020
1772020
Varicella zoster virus latency
E Eshleman, A Shahzad, RJ Cohrs
Future virology 6 (3), 341-355, 2011
822011
Commensal segmented filamentous bacteria-derived retinoic acid primes host defense to intestinal infection
V Woo, EM Eshleman, S Hashimoto-Hill, J Whitt, S Wu, L Engleman, ...
Cell host & microbe 29 (12), 1744-1756. e5, 2021
622021
Type I interferons in bacterial infections: taming of myeloid cells and possible implications for autoimmunity
EM Eshleman, LL Lenz
Frontiers in immunology 5, 431, 2014
612014
Type I IFNs downregulate myeloid cell IFN-γ receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription
SJ Kearney, C Delgado, EM Eshleman, KK Hill, BP O’Connor, LL Lenz
The Journal of Immunology 191 (6), 3384-3392, 2013
562013
Histone deacetylase inhibition by gut microbe-generated short-chain fatty acids entrains intestinal epithelial circadian rhythms
JA Fawad, DH Luzader, GF Hanson, TJ Moutinho Jr, CA McKinney, ...
Gastroenterology 163 (5), 1377-1390. e11, 2022
552022
Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity
EM Eshleman, TY Shao, V Woo, T Rice, L Engleman, BJ Didriksen, ...
The Journal of clinical investigation 133 (4), 2023
332023
Down regulation of macrophage IFNGR1 exacerbates systemic L. monocytogenes infection
EM Eshleman, C Delgado, SJ Kearney, RS Friedman, LL Lenz
PLoS Pathogens 13 (5), e1006388, 2017
322017
Microbiota inhibit epithelial pathogen adherence by epigenetically regulating C-type lectin expression
V Woo, EM Eshleman, T Rice, J Whitt, BA Vallance, T Alenghat
Frontiers in Immunology 10, 928, 2019
272019
Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity
EM Eshleman, T Rice, C Potter, A Waddell, S Hashimoto-Hill, V Woo, ...
Immunity 57 (2), 319-332. e6, 2024
262024
Human anti-varicella-zoster virus (VZV) recombinant monoclonal antibody produced after Zostavax immunization recognizes the gH/gL complex and neutralizes VZV infection
M Birlea, GP Owens, EM Eshleman, A Ritchie, I Traktinskiy, N Bos, S Seitz, ...
Journal of Virology 87 (1), 415-421, 2013
242013
Epithelial sensing of microbiota-derived signals
EM Eshleman, T Alenghat
Genes & Immunity 22 (5), 237-246, 2021
172021
IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation
GR Overcast, HE Meibers, EM Eshleman, I Saha, L Waggoner, KN Patel, ...
Journal of Experimental Medicine 220 (6), e20212523, 2023
102023
Ligand-induced IFNGR1 down-regulation calibrates myeloid cell IFNγ responsiveness
WJ Crisler, EM Eshleman, LL Lenz
Life Science Alliance 2 (5), 2019
72019
Myeloid cell responsiveness to interferon-gamma is sufficient for initial resistance to Listeria monocytogenes
EM Eshleman, N Bortell, DS McDermott, WJ Crisler, LL Lenz
Current research in immunology 1, 1-9, 2020
42020
Epithelial cell intrinsic IL-1R signaling regulates intestinal homeostasis and inflammation
G Overcast, E Eshleman, T Alenghat, C Pasare
The Journal of Immunology 204 (1_Supplement), 235.6-235.6, 2020
32020
Type I interferons down regulate myeloid cell IFNGR by inducing recruitment of an Egr3/Nab1 complex that silences ifngr1 transcription
SJ Kearney, C Delgado, EM Eshleman, KK Hill, BP O'Connor, LL Lenz
Journal of immunology (Baltimore, Md.: 1950) 191 (6), 3384, 2013
32013
Epithelial regulation of microbiota-immune cell dynamics
BJ Didriksen, EM Eshleman, T Alenghat
Mucosal Immunology, 2024
22024
Microbiota dampen type 2 immunity by epigenetically restricting tuft cell differentiation
EM Eshleman, T Rice, C Potter, V Woo, S Field, S Hashimoto-Hill, ...
The Journal of Immunology 210 (1_Supplement), 150.08-150.08, 2023
22023
Microbiota‐derived butyrate dampens linaclotide stimulation of the guanylate cyclase C pathway in patient‐derived colonoids
A Velez Lopez, A Waddell, S Antonacci, D Castillo, N Santucci, ...
Neurogastroenterology & Motility 35 (12), e14681, 2023
12023
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