| IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses T Krausgruber, K Blazek, T Smallie, S Alzabin, H Lockstone, N Sahgal, ... Nature immunology 12 (3), 231-238, 2011 | 1511 | 2011 |
| Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling J Adam, E Hatipoglu, L O'Flaherty, N Ternette, N Sahgal, H Lockstone, ... Cancer cell 20 (4), 524-537, 2011 | 634 | 2011 |
| Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties E Billerbeck, YH Kang, L Walker, H Lockstone, S Grafmueller, V Fleming, ... Proceedings of the National Academy of Sciences 107 (7), 3006-3011, 2010 | 437 | 2010 |
| Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes BM Herrera, HE Lockstone, JM Taylor, M Ria, A Barrett, S Collins, ... Diabetologia 53, 1099-1109, 2010 | 363 | 2010 |
| Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain SC Vernes, PL Oliver, E Spiteri, HE Lockstone, R Puliyadi, JM Taylor, ... PLoS genetics 7 (7), e1002145, 2011 | 341 | 2011 |
| CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages JR Fergusson, KE Smith, VM Fleming, N Rajoriya, EW Newell, ... Cell reports 9 (3), 1075-1088, 2014 | 329 | 2014 |
| Gene expression profiling in the adult Down syndrome brain HE Lockstone, LW Harris, JE Swatton, MT Wayland, AJ Holland, S Bahn Genomics 90 (6), 647-660, 2007 | 293 | 2007 |
| Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes MM Ryan, HE Lockstone, SJ Huffaker, MT Wayland, MJ Webster, S Bahn Molecular psychiatry 11 (10), 965-978, 2006 | 256 | 2006 |
| Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells H Dolatshad, A Pellagatti, M Fernandez-Mercado, BH Yip, L Malcovati, ... Leukemia 29 (5), 1092-1103, 2015 | 238 | 2015 |
| Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations A Pellagatti, RN Armstrong, V Steeples, E Sharma, E Repapi, S Singh, ... Blood, The Journal of the American Society of Hematology 132 (12), 1225-1240, 2018 | 222 | 2018 |
| Sequencing of human genomes with nanopore technology R Bowden, RW Davies, A Heger, AT Pagnamenta, M de Cesare, ... Nature communications 10 (1), 1869, 2019 | 221 | 2019 |
| 53BP1 integrates DNA repair and p53-dependent cell fate decisions via distinct mechanisms R Cuella-Martin, C Oliveira, HE Lockstone, S Snellenberg, N Grolmusova, ... Molecular cell 64 (1), 51-64, 2016 | 200 | 2016 |
| BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors T Reisländer, EP Lombardi, FJ Groelly, A Miar, M Porru, S Di Vito, ... Nature communications 10 (1), 3143, 2019 | 191 | 2019 |
| Independent protein-profiling studies show a decrease in apolipoprotein A1 levels in schizophrenia CSF, brain and peripheral tissues JTJ Huang, L Wang, S Prabakaran, M Wengenroth, HE Lockstone, ... Molecular psychiatry 13 (12), 1118-1128, 2008 | 179 | 2008 |
| Expression of Idh1R132H in the murine subventricular zone stem cell niche recapitulates features of early gliomagenesis C Bardella, O Al-Dalahmah, D Krell, P Brazauskas, K Al-Qahtani, ... Cancer cell 30 (4), 578-594, 2016 | 175 | 2016 |
| MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes BM Herrera, HE Lockstone, JM Taylor, QF Wills, PJ Kaisaki, A Barrett, ... BMC medical genomics 2, 1-11, 2009 | 166 | 2009 |
| 2-D DIGE analysis of liver and red blood cells provides further evidence for oxidative stress in schizophrenia S Prabakaran, M Wengenroth, HE Lockstone, K Lilley, FM Leweke, ... Journal of proteome research 6 (1), 141-149, 2007 | 143 | 2007 |
| Gene expression in the prefrontal cortex during adolescence: implications for the onset of schizophrenia LW Harris, HE Lockstone, P Khaitovich, CS Weickert, MJ Webster, S Bahn BMC medical genomics 2, 1-14, 2009 | 135 | 2009 |
| Metabolic changes in schizophrenia and human brain evolution P Khaitovich, HE Lockstone, MT Wayland, TM Tsang, SD Jayatilaka, ... Genome biology 9, 1-11, 2008 | 129 | 2008 |
| Exon array data analysis using Affymetrix power tools and R statistical software HE Lockstone Briefings in bioinformatics 12 (6), 634-644, 2011 | 127 | 2011 |
Jean-Baptiste CazierCentre for Computational Biology, University of Birmingham, UKEmail verificata su bham.ac.uk