Paul B. McCray, Jr., M.D.

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David MeyerholzProfessor, Department of Pathology, Carver College of Medicine, University of IowaEmail verificata su uiowa.edu
Patrick SinnProfessor of Pediatrics, University of IowaEmail verificata su uiowa.edu
Joseph ZabnerUniversity of IowaEmail verificata su uiowa.edu
hongpeng jiaJohns Hopkins University School of MedicineEmail verificata su jhmi.edu
Stanley Perlmanuniversity of iowaEmail verificata su uiowa.edu
David A. StoltzProfessor of MedicineEmail verificata su uiowa.edu
Alejandro PezzuloAssistant Professor, Pulmonary and Critical Care Medicine, University of Iowa Carver College ofEmail verificata su uiowa.edu
Shyam RamachandranSanofiEmail verificata su sanofi.com
Kim A. BrogdenProfessor, College of Dentistry, University of IowaEmail verificata su uiowa.edu
Mark BehlkeIntegrated DNA TechnologiesEmail verificata su idtdna.com
Mahmoud Abou AlaiwaAssistant Professor , University of IowaEmail verificata su uiowa.edu
John F. Engelhardt, Ph.D.Professor and Chair, Department of Anatomy and Cell BiologyEmail verificata su uiowa.edu
Tomas GanzDistinguished Professor of Medicine and Pathology, UCLAEmail verificata su mednet.ucla.edu
Todd ScheetzUniversity of IowaEmail verificata su uiowa.edu
Tom GallagherProfessor of Microbiology and Immunology, Loyola University ChicagoEmail verificata su luc.edu
Anthony J FischerUniversity of IowaEmail verificata su uiowa.edu
Jian ZhengDepartment of Medical Ultrasonics, Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, ChinaEmail verificata su mail2.sysu.edu.cn
Cliff TaggartQueen's University BelfastEmail verificata su qub.ac.uk
Thomas MoningerAssistant Director, Central Microscopy Research Facility, University of IowaEmail verificata su uiowa.edu
Peter S. ThorneUniversity Distinguished Chair; Professor, Occup & Envir Health; Dir, Human Tox. PrgmEmail verificata su uiowa.edu

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Paul B. McCray, Jr., M.D.

Professor, Department of Pediatrics, Pappajohn Biomedical Institute, University of Iowa

Email verificata su uiowa.edu - Home page

cystic fibrosis host-pathogen interactions innate immunity gene therapy


Titolo Ordina per citazioni Ordina per anno Ordina per titolo	Citata da Citata da	Anno
ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia HP Jia, DC Look, L Shi, M Hickey, L Pewe, J Netland, M Farzan, ... Journal of virology 79 (23), 14614-14621, 2005	1194	2005
Lethal Infection of K18-hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus PB McCray Jr, L Pewe, C Wohlford-Lenane, M Hickey, L Manzel, L Shi, ... Journal of virology 81 (2), 813-821, 2007	1127	2007
Rapid “open-source” engineering of customized zinc-finger nucleases for highly efficient gene modification ML Maeder, S Thibodeau-Beganny, A Osiak, DA Wright, RM Anthony, ... Molecular cell 31 (2), 294-301, 2008	1004	2008
Human beta-defensin-1: an antimicrobial peptide of urogenital tissues. EV Valore, CH Park, AJ Quayle, KR Wiles, PB McCray, T Ganz The Journal of clinical investigation 101 (8), 1633-1642, 1998	999	1998
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung AA Pezzulo, XX Tang, MJ Hoegger, MH Abou Alaiwa, S Ramachandran, ... Nature 487 (7405), 109-113, 2012	988	2012
Current prospects for RNA interference-based therapies BL Davidson, PB McCray Jr Nature Reviews Genetics 12 (5), 329-340, 2011	933	2011
Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs CS Rogers, DA Stoltz, DK Meyerholz, LS Ostedgaard, T Rokhlina, PJ Taft, ... Science 321 (5897), 1837-1841, 2008	900	2008
Production of β-defensins by human airway epithelia PK Singh, HP Jia, K Wiles, J Hesselberth, L Liu, BAD Conway, ... Proceedings of the National Academy of Sciences 95 (25), 14961-14966, 1998	821	1998
Adherens junction protein nectin-4 is the epithelial receptor for measles virus MD Mühlebach, M Mateo, PL Sinn, S Prüfer, KM Uhlig, VHJ Leonard, ... Nature 480 (7378), 530-533, 2011	681	2011
Discovery of five conserved β-defensin gene clusters using a computational search strategy BC Schutte, JP Mitros, JA Bartlett, JD Walters, HP Jia, MJ Welsh, ... Proceedings of the National Academy of Sciences 99 (4), 2129-2133, 2002	676	2002
Antimicrobial peptides in animals and their role in host defences KA Brogden, M Ackermann, PB McCray Jr, BF Tack International journal of antimicrobial agents 22 (5), 465-478, 2003	670	2003
IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes R Channappanavar, AR Fehr, J Zheng, C Wohlford-Lenane, ... The Journal of clinical investigation 129 (9), 3625-3639, 2019	653	2019
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth DA Stoltz, DK Meyerholz, AA Pezzulo, S Ramachandran, MP Rogan, ... Science translational medicine 2 (29), 29ra31-29ra31, 2010	589	2010
Middle East respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4 K Li, C Wohlford-Lenane, S Perlman, J Zhao, AK Jewell, LR Reznikov, ... The Journal of infectious diseases 213 (5), 712-722, 2016	548	2016
A SARS-CoV-2 infection model in mice demonstrates protection by neutralizing antibodies AO Hassan, JB Case, ES Winkler, LB Thackray, NM Kafai, AL Bailey, ... Cell 182 (3), 744-753. e4, 2020	541	2020
Rapid generation of a mouse model for Middle East respiratory syndrome J Zhao, K Li, C Wohlford-Lenane, SS Agnihothram, C Fett, J Zhao, ... Proceedings of the National Academy of Sciences 111 (13), 4970-4975, 2014	531	2014
Production of β-defensin antimicrobial peptides by the oral mucosa and salivary glands M Mathews, HP Jia, JM Guthmiller, G Losh, S Graham, GK Johnson, ... Infection and immunity 67 (6), 2740-2745, 1999	523	1999
The solution structures of the human β-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus DJ Schibli, HN Hunter, V Aseyev, TD Starner, JM Wiencek, PB McCray, ... Journal of Biological Chemistry 277 (10), 8279-8289, 2002	522	2002
Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-α secretion through IKK regulation of NF-κB S Sanlioglu, CM Williams, L Samavati, NS Butler, G Wang, PB McCray, ... Journal of Biological Chemistry 276 (32), 30188-30198, 2001	502	2001
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice J Zheng, LYR Wong, K Li, AK Verma, ME Ortiz, C Wohlford-Lenane, ... Nature 589 (7843), 603-607, 2021	478	2021

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