Preferential binding of a G-quadruplex ligand to human chromosome ends C Granotier, G Pennarun, L Riou, F Hoffschir, LR Gauthier, A De Cian, ... Nucleic acids research 33 (13), 4182-4190, 2005 | 329 | 2005 |
Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands G Pennarun, C Granotier, LR Gauthier, D Gomez, F Hoffschir, E Mandine, ... Oncogene 24 (18), 2917-2928, 2005 | 315 | 2005 |
Telomerase downregulation induced by the G‐quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing D Gomez, T Lemarteleur, L Lacroix, P Mailliet, JL Mergny, JF Riou Nucleic acids research 32 (1), 371-379, 2004 | 301 | 2004 |
Stabilization of the c-myc gene promoter quadruplex by specific ligands’ inhibitors of telomerase T Lemarteleur, D Gomez, R Paterski, E Mandine, P Mailliet, JF Riou Biochemical and biophysical research communications 323 (3), 802-808, 2004 | 271 | 2004 |
The G-quadruplex Ligand Telomestatin Inhibits POT1 Binding to Telomeric Sequences In vitro and Induces GFP-POT1 Dissociation from Telomeres in Human Cells D Gomez, MF O'Donohue, T Wenner, C Douarre, J Macadré, P Koebel, ... Cancer research 66 (14), 6908-6912, 2006 | 256 | 2006 |
Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells D Gomez, T Wenner, B Brassart, C Douarre, MF O'Donohue, V El Khoury, ... Journal of Biological Chemistry 281 (50), 38721-38729, 2006 | 248 | 2006 |
Alternative end-joining pathway (s): bricolage at DNA breaks P Frit, N Barboule, Y Yuan, D Gomez, P Calsou DNA repair 17, 81-97, 2014 | 213 | 2014 |
A G-quadruplex structure within the 5′-UTR of TRF2 mRNA represses translation in human cells D Gomez, A Guedin, JL Mergny, B Salles, JF Riou, MP Teulade-Fichou, ... Nucleic acids research 38 (20), 7187-7198, 2010 | 204 | 2010 |
Interaction of telomestatin with the telomeric single-strand overhang D Gomez, R Paterski, T Lemarteleur, K Shin-Ya, JL Mergny, JF Riou Journal of Biological Chemistry 279 (40), 41487-41494, 2004 | 188 | 2004 |
Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks Q Cheng, N Barboule, P Frit, D Gomez, O Bombarde, B Couderc, GS Ren, ... Nucleic acids research 39 (22), 9605-9619, 2011 | 153 | 2011 |
Modelación de las funciones de crecimiento aplicadas a la producción animal DA Agudelo Gómez, MF Cerón Muñoz, LF Restrepo Betancur Revista Colombiana de Ciencias Pecuarias 21 (1), 39-58, 2008 | 152 | 2008 |
Reconocimiento de formas y visión artificial DM Gómez-Allende Ra-ma, 1993 | 144 | 1993 |
Detection of telomerase inhibitors based on G-quadruplex ligands by a modified telomeric repeat amplification protocol assay D Gomez, JL Mergny, JF Riou Cancer research 62 (12), 3365-3368, 2002 | 132 | 2002 |
A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells B Brassart, D Gomez, A De Cian, R Paterski, A Montagnac, KH Qui, ... Molecular pharmacology 72 (3), 631-640, 2007 | 112 | 2007 |
Improvement of porphyrins for G-quadruplex DNA targeting C Romera, O Bombarde, R Bonnet, D Gomez, P Dumy, P Calsou, ... Biochimie 93 (8), 1310-1317, 2011 | 102 | 2011 |
TRF2/RAP1 and DNA–PK mediate a double protection against joining at telomeric ends O Bombarde, C Boby, D Gomez, P Frit, MJ Giraud‐Panis, E Gilson, ... The EMBO journal 29 (9), 1573-1584, 2010 | 91 | 2010 |
Topoisomerase IIIα is required for normal proliferation and telomere stability in alternative lengthening of telomeres N Temime‐Smaali, L Guittat, T Wenner, E Bayart, C Douarre, D Gomez, ... The EMBO journal 27 (10), 1513-1524, 2008 | 82 | 2008 |
Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase D Gomez, N Aouali, A Renaud, C Douarre, K Shin-Ya, J Tazi, S Martinez, ... Cancer research 63 (19), 6149-6153, 2003 | 79 | 2003 |
Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration D Gomez, N Aouali, A Londono-Vallejo, L Lacroix, F Mégnin-Chanet, ... Journal of Biological Chemistry 278 (50), 50554-50562, 2003 | 76 | 2003 |
Transcription-associated topoisomerase 2α (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands M Bossaert, A Pipier, JF Riou, C Noirot, LT Nguyên, RF Serre, O Bouchez, ... Elife 10, e65184, 2021 | 62 | 2021 |