Identification of ubiquitin ligases required for skeletal muscle atrophy SC Bodine, E Latres, S Baumhueter, VKM Lai, L Nunez, BA Clarke, ... Science 294 (5547), 1704-1708, 2001 | 4089 | 2001 |
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. H Flores-Rozas, Z Kelman, FB Dean, ZQ Pan, JW Harper, SJ Elledge, ... Proceedings of the National Academy of Sciences 91 (18), 8655-8659, 1994 | 610 | 1994 |
The cullin protein family A Sarikas, T Hartmann, ZQ Pan Genome biology 12, 1-12, 2011 | 579 | 2011 |
Nedd8 on cullin: building an expressway to protein destruction ZQ Pan, A Kentsis, DC Dias, K Yamoah, K Wu Oncogene 23 (11), 1985-1997, 2004 | 507 | 2004 |
Inhibition of p21‐mediated ROS accumulation can rescue p21‐induced senescence S Macip, M Igarashi, L Fang, A Chen, ZQ Pan, SW Lee, SA Aaronson The EMBO journal, 2002 | 457 | 2002 |
Recruitment of a ROC1–CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of IκBα P Tan, SY Fuchs, A Chen, K Wu, C Gomez, Z Ronai, ZQ Pan Molecular cell 3 (4), 527-533, 1999 | 432 | 1999 |
SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53 T Buschmann, SY Fuchs, CG Lee, ZQ Pan, Z Ronai Cell 101 (7), 753-762, 2000 | 376 | 2000 |
Commensal bacteria modulate cullin‐dependent signaling via generation of reactive oxygen species A Kumar, H Wu, LS Collier‐Hyams, JM Hansen, T Li, K Yamoah, ZQ Pan, ... The EMBO journal 26 (21), 4457-4466, 2007 | 304 | 2007 |
Studies on the activator 1 protein complex, an accessory factor for proliferating cell nuclear antigen-dependent DNA polymerase delta. SH Lee, AD Kwong, ZQ Pan, J Hurwitz Journal of Biological Chemistry 266 (1), 594-602, 1991 | 296 | 1991 |
Autoubiquitination of the BRCA1· BARD1 RING ubiquitin ligase A Chen, FE Kleiman, JL Manley, T Ouchi, ZQ Pan Journal of Biological Chemistry 277 (24), 22085-22092, 2002 | 289 | 2002 |
Clamp loading, unloading and intrinsic stability of the PCNA, β and gp45 sliding clamps of human, E. coli and T4 replicases N Yao, J Turner, Z Kelman, PT Stukenberg, F Dean, D Shechter, ZQ Pan, ... Genes to Cells 1 (1), 101-113, 1996 | 282 | 1996 |
The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation X Xu, A Sarikas, DC Dias-Santagata, G Dolios, PJ Lafontant, SC Tsai, ... Molecular cell 30 (4), 403-414, 2008 | 263 | 2008 |
Synthesis of DNA by DNA polymerase epsilon in vitro. SH Lee, ZQ Pan, AD Kwong, PM Burgers, J Hurwitz Journal of Biological Chemistry 266 (33), 22707-22717, 1991 | 258 | 1991 |
p53 Is Phosphorylated by CDK7-Cyclin H in a p36MAT1-Dependent Manner LJ Ko, SY Shieh, X Chen, L Jayaraman, K Tamai, Y Taya, C Prives, ... Molecular and cellular biology 17 (12), 7220-7229, 1997 | 250 | 1997 |
Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization K Wu, A Chen, ZQ Pan Journal of Biological Chemistry 275 (41), 32317-32324, 2000 | 247 | 2000 |
The Mdm2 RING domain C‐terminus is required for supramolecular assembly and ubiquitin ligase activity MV Poyurovsky, C Priest, A Kentsis, KLB Borden, ZQ Pan, N Pavletich, ... The EMBO journal 26 (1), 90-101, 2007 | 241 | 2007 |
Identification and characterization of DEN1, a deneddylase of the ULP family T Gan-Erdene, K Nagamalleswari, L Yin, K Wu, ZQ Pan, KD Wilkinson Journal of Biological Chemistry 278 (31), 28892-28900, 2003 | 240 | 2003 |
HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IκB and β-catenin SY Fuchs, A Chen, Y Xiong, ZQ Pan, Z Ronai Oncogene 18 (12), 2039-2046, 1999 | 239 | 1999 |
Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21 ZQ Pan, JT Reardon, L Li, H Flores-Rozas, R Legerski, A Sancar, ... Journal of Biological Chemistry 270 (37), 22008-22016, 1995 | 239 | 1995 |
DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1 K Wu, K Yamoah, G Dolios, T Gan-Erdene, P Tan, A Chen, C Lee, N Wei, ... Journal of Biological Chemistry 278 (31), 28882-28891, 2003 | 222 | 2003 |