| The causes and consequences of genetic heterogeneity in cancer evolution RA Burrell, N McGranahan, J Bartek, C Swanton Nature 501 (7467), 338-345, 2013 | 2628 | 2013 |
| Replication stress links structural and numerical cancer chromosomal instability RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ... Nature 494 (7438), 492-496, 2013 | 957 | 2013 |
| Tumour heterogeneity and the evolution of polyclonal drug resistance RA Burrell, C Swanton Molecular oncology 8 (6), 1095-1111, 2014 | 488 | 2014 |
| Cancer chromosomal instability: therapeutic and diagnostic challenges: ‘Exploring aneuploidy: the significance of chromosomal imbalance’review series N McGranahan, RA Burrell, D Endesfelder, MR Novelli, C Swanton EMBO reports 13 (6), 528-538, 2012 | 486 | 2012 |
| Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution SM Dewhurst, N McGranahan, RA Burrell, AJ Rowan, E Grönroos, ... Cancer discovery 4 (2), 175-185, 2014 | 452 | 2014 |
| Cancer: evolution within a lifetime M Gerlinger, N McGranahan, SM Dewhurst, RA Burrell, I Tomlinson, ... Annual review of genetics 48 (1), 215-236, 2014 | 247 | 2014 |
| Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer R Roylance, D Endesfelder, P Gorman, RA Burrell, J Sander, I Tomlinson, ... Cancer epidemiology, biomarkers & prevention 20 (10), 2183-2194, 2011 | 198 | 2011 |
| SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair N Kanu, E Grönroos, P Martinez, RA Burrell, X Yi Goh, J Bartkova, ... Oncogene 34 (46), 5699-5708, 2015 | 192 | 2015 |
| Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast … N Juul, Z Szallasi, AC Eklund, Q Li, RA Burrell, M Gerlinger, V Valero, ... The lancet oncology 11 (4), 358-365, 2010 | 151 | 2010 |
| Genome‐wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target M Gerlinger, CR Santos, B Spencer‐Dene, P Martinez, D Endesfelder, ... The Journal of pathology 227 (2), 146-156, 2012 | 136 | 2012 |
| Chromosomal instability: a composite phenotype that influences sensitivity to chemotherapy SE McClelland, RA Burrell, C Swanton Cell cycle 8 (20), 3262-3266, 2009 | 136 | 2009 |
| BCL9L dysfunction impairs caspase-2 expression permitting aneuploidy tolerance in colorectal cancer C López-García, L Sansregret, E Domingo, N McGranahan, S Hobor, ... Cancer cell 31 (1), 79-93, 2017 | 102 | 2017 |
| Parallel evolution of tumour subclones mimics diversity between tumours P Martinez, NJ Birkbak, M Gerlinger, N McGranahan, RA Burrell, ... The Journal of pathology 230 (4), 356-364, 2013 | 102 | 2013 |
| Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+ Breast Cancer D Endesfelder, RA Burrell, N Kanu, N McGranahan, M Howell, PJ Parker, ... Cancer research 74 (17), 4853-4863, 2014 | 86 | 2014 |
| The evolution of the unstable cancer genome RA Burrell, C Swanton Current opinion in genetics & development 24, 61-67, 2014 | 86 | 2014 |
| Breast cancer genome heterogeneity: a challenge to personalised medicine? C Swanton, RA Burrell, PA Futreal Breast Cancer Research 13, 1-2, 2011 | 71 | 2011 |
| RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress N Kanu, T Zhang, RA Burrell, A Chakraborty, J Cronshaw, C DaCosta, ... Oncogene 35 (30), 4009-4019, 2016 | 59 | 2016 |
| Targeting chromosomal instability and tumour heterogeneity in HER2‐positive breast cancer RA Burrell, N Juul, SR Johnston, JS Reis‐Filho, Z Szallasi, C Swanton Journal of cellular biochemistry 111 (4), 782-790, 2010 | 54 | 2010 |
| Re-evaluating clonal dominance in cancer evolution RA Burrell, C Swanton Trends in Cancer 2 (5), 263-276, 2016 | 44 | 2016 |
| Expression of regulators of mitotic fidelity are associated with intercellular heterogeneity and chromosomal instability in primary breast cancer R Roylance, D Endesfelder, M Jamal-Hanjani, RA Burrell, P Gorman, ... Breast cancer research and treatment 148, 221-229, 2014 | 14 | 2014 |
Nicholas McGranahanGroup Leader, CRUK Lung Cancer Centre of Excellence, UCL Cancer InstituteEmail verificata su ucl.ac.uk
