Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles ME Davis, JE Zuckerman, CHJ Choi, D Seligson, A Tolcher, CA Alabi, ... Nature 464 (7291), 1067-1070, 2010 | 3004 | 2010 |
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling G Sahay, W Querbes, C Alabi, A Eltoukhy, S Sarkar, C Zurenko, ... Nature biotechnology 31 (7), 653-658, 2013 | 887 | 2013 |
Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticles CHJ Choi, CA Alabi, P Webster, ME Davis Proceedings of the National Academy of Sciences 107 (3), 1235-1240, 2010 | 872 | 2010 |
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates Y Dong, KT Love, JR Dorkin, S Sirirungruang, Y Zhang, D Chen, ... Proceedings of the National Academy of Sciences 111 (11), 3955-3960, 2014 | 533 | 2014 |
Sequence-defined polymers via orthogonal allyl acrylamide building blocks M Porel, CA Alabi Journal of the American Chemical Society 136 (38), 13162-13165, 2014 | 232 | 2014 |
Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets RD de Vries, KS Schmitz, FT Bovier, C Predella, J Khao, D Noack, ... Science 371 (6536), 1379-1382, 2021 | 204 | 2021 |
Pharmacokinetics and tumor dynamics of the nanoparticle IT-101 from PET imaging and tumor histological measurements T Schluep, J Hwang, IJ Hildebrandt, J Czernin, CHJ Choi, CA Alabi, ... Proceedings of the National Academy of Sciences 106 (27), 11394-11399, 2009 | 201 | 2009 |
Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery CA Alabi, KT Love, G Sahay, H Yin, KM Luly, R Langer, DG Anderson Proceedings of the National Academy of Sciences 110 (32), 12881-12886, 2013 | 193 | 2013 |
Effect of molecular weight of amine end-modified poly (β-amino ester) s on gene delivery efficiency and toxicity AA Eltoukhy, DJ Siegwart, CA Alabi, JS Rajan, R Langer, DG Anderson Biomaterials 33 (13), 3594-3603, 2012 | 164 | 2012 |
Sequence-defined bioactive macrocycles via an acid-catalysed cascade reaction M Porel, DN Thornlow, NN Phan, CA Alabi Nature chemistry 8 (6), 590-596, 2016 | 151 | 2016 |
Degradable terpolymers with alkyl side chains demonstrate enhanced gene delivery potency and nanoparticle stability AA Eltoukhy, D Chen, CA Alabi, R Langer, DG Anderson Advanced Materials (Deerfield Beach, Fla.) 25 (10), 2013 | 145 | 2013 |
Amino acid-, peptide-and polypeptide-lipids, isomers, compositions, and uses thereof Y Dong, KT Love, RS Langer, DG Anderson, D Chen, Y Chen, AJ Vegas, ... US Patent 9,512,073, 2016 | 126 | 2016 |
Synergistic silencing: combinations of lipid-like materials for efficacious siRNA delivery KA Whitehead, G Sahay, GZ Li, KT Love, CA Alabi, M Ma, C Zurenko, ... Molecular Therapy 19 (9), 1688-1694, 2011 | 86 | 2011 |
Attacking the genome: emerging siRNA nanocarriers from concept to clinic C Alabi, A Vegas, D Anderson Current opinion in pharmacology 12 (4), 427-433, 2012 | 77 | 2012 |
FRET-labeled siRNA probes for tracking assembly and disassembly of siRNA nanocomplexes CA Alabi, KT Love, G Sahay, T Stutzman, WT Young, R Langer, ... ACS nano 6 (7), 6133-6141, 2012 | 74 | 2012 |
1, 3, 5-triazinane-2, 4, 6-trione derivatives and uses thereof Y Dong, AC Alabi, H Yin, JR Dorkin, D Chen, RS Langer, DG Anderson, ... US Patent 9,315,472, 2016 | 71 | 2016 |
Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo Y Dong, AA Eltoukhy, CA Alabi, OF Khan, O Veiseh, JR Dorkin, ... Advanced healthcare materials 3 (9), 1392, 2014 | 69 | 2014 |
Sequence-defined backbone modifications regulate antibacterial activity of oligoTEAs M Porel, DN Thornlow, CM Artim, CA Alabi ACS chemical biology 12 (3), 715-723, 2017 | 61 | 2017 |
Biomimetic electronic devices for measuring bacterial membrane disruption C Pitsalidis, AM Pappa, M Porel, CM Artim, GC Faria, DD Duong, ... Advanced Materials 30 (39), 1803130, 2018 | 57 | 2018 |
Thiol–Ene Networks from Sequence-Defined Polyurethane Macromers EA Hoff, GX De Hoe, CM Mulvaney, MA Hillmyer, CA Alabi Journal of the American Chemical Society 142 (14), 6729-6736, 2020 | 54 | 2020 |