The effect of pore geometry on the in vitro biological behavior of human periosteum-derived cells seeded on selective laser-melted Ti6Al4V bone scaffolds S Van Bael, YC Chai, S Truscello, M Moesen, G Kerckhofs, ... Acta biomaterialia 8 (7), 2824-2834, 2012 | 831 | 2012 |
A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells AMC Barradas, HAM Fernandes, N Groen, YC Chai, J Schrooten, ... Biomaterials 33 (11), 3205-3215, 2012 | 471 | 2012 |
Bone regeneration performance of surface-treated porous titanium SA Yavari, J van der Stok, YC Chai, R Wauthle, ZT Birgani, P Habibovic, ... Biomaterials 35 (24), 6172-6181, 2014 | 325 | 2014 |
Current views on calcium phosphate osteogenicity and the translation into effective bone regeneration strategies YC Chai, A Carlier, J Bolander, SJ Roberts, L Geris, J Schrooten, ... Acta biomaterialia 8 (11), 3876-3887, 2012 | 323 | 2012 |
Probing the Osteoinductive Effect of Calcium Phosphate by Using an In Vitro Biomimetic Model YC Chai, SJ Roberts, J Schrooten, FP Luyten Tissue Engineering Part A 17 (7-8), 1083-1097, 2011 | 137 | 2011 |
Mechanisms of ectopic bone formation by human osteoprogenitor cells on CaP biomaterial carriers YC Chai, SJ Roberts, E Desmet, G Kerckhofs, N van Gastel, L Geris, ... Biomaterials 33 (11), 3127-3142, 2012 | 122 | 2012 |
A computational model for cell/ECM growth on 3D surfaces using the level set method: a bone tissue engineering case study Y Guyot, I Papantoniou, YC Chai, S Van Bael, J Schrooten, L Geris Biomechanics and modeling in mechanobiology 13, 1361-1371, 2014 | 116 | 2014 |
Preclinical and clinical advances in transposon-based gene therapy J Tipanee, YC Chai, T VandenDriessche, MK Chuah Bioscience reports 37 (6), BSR20160614, 2017 | 94 | 2017 |
Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells S Dastidar, S Ardui, K Singh, D Majumdar, N Nair, Y Fu, D Reyon, ... Nucleic acids research 46 (16), 8275-8298, 2018 | 91 | 2018 |
Ectopic bone formation by 3D porous calcium phosphate-Ti6Al4V hybrids produced by perfusion electrodeposition YC Chai, G Kerckhofs, SJ Roberts, S Van Bael, E Schepers, J Vleugels, ... Biomaterials 33 (16), 4044-4058, 2012 | 79 | 2012 |
Early BMP, Wnt and Ca2+/PKC pathway activation predicts the bone forming capacity of periosteal cells in combination with calcium phosphates J Bolander, YC Chai, L Geris, J Schrooten, D Lambrechts, SJ Roberts, ... Biomaterials 86, 106-118, 2016 | 64 | 2016 |
Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects WL Tam, L Freitas Mendes, X Chen, R Lesage, I Van Hoven, E Leysen, ... Stem cell research & therapy 12, 1-16, 2021 | 62 | 2021 |
Advancing osteochondral tissue engineering: bone morphogenetic protein, transforming growth factor, and fibroblast growth factor signaling drive ordered differentiation of … LF Mendes, H Katagiri, WL Tam, YC Chai, L Geris, SJ Roberts, FP Luyten Stem cell research & therapy 9, 1-13, 2018 | 60 | 2018 |
Cell based advanced therapeutic medicinal products for bone repair: Keep it simple? J Leijten, YC Chai, I Papantoniou, L Geris, J Schrooten, FP Luyten Advanced drug delivery reviews 84, 30-44, 2015 | 58 | 2015 |
The combined mechanism of bone morphogenetic protein-and calcium phosphate-induced skeletal tissue formation by human periosteum derived cells. J Bolander, W Ji, L Geris, V Bloemen, YC Chai, J Schrooten, FP Luyten European Cells and Materials 31, 2016 | 57 | 2016 |
In vitro cell-biological performance and structural characterization of selective laser sintered and plasma surface functionalized polycaprolactone scaffolds for bone regeneration S Van Bael, T Desmet, YC Chai, G Pyka, P Dubruel, JP Kruth, J Schrooten Materials Science and Engineering: C 33 (6), 3404-3412, 2013 | 55 | 2013 |
Perfusion electrodeposition of calcium phosphate on additive manufactured titanium scaffolds for bone engineering YC Chai, S Truscello, S Van Bael, FP Luyten, J Vleugels, J Schrooten Acta biomaterialia 7 (5), 2310-2319, 2011 | 54 | 2011 |
Effects of anodizing parameters and heat treatment on nanotopographical features, bioactivity, and cell culture response of additively manufactured porous titanium SA Yavari, YC Chai, AJ Böttger, R Wauthle, J Schrooten, H Weinans, ... Materials Science and Engineering: C 51, 132-138, 2015 | 53 | 2015 |
Gelatin functionalised porous titanium alloy implants for orthopaedic applications E Vanderleyden, S Van Bael, YC Chai, JP Kruth, J Schrooten, P Dubruel Materials Science and Engineering: C 42, 396-404, 2014 | 47 | 2014 |
Combinatorial analysis of growth factors reveals the contribution of bone morphogenetic proteins to chondrogenic differentiation of human periosteal cells LF Mendes, WL Tam, YC Chai, L Geris, FP Luyten, SJ Roberts Tissue Engineering Part C: Methods 22 (5), 473-486, 2016 | 46 | 2016 |