Glutathionylation of human thioredoxin: a possible crosstalk between the glutathione and thioredoxin systems S Casagrande, V Bonetto, M Fratelli, E Gianazza, I Eberini, T Massignan, ... Proceedings of the National Academy of Sciences 99 (15), 9745-9749, 2002 | 426 | 2002 |
Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis F Casoni, M Basso, T Massignan, E Gianazza, C Cheroni, M Salmona, ... Journal of Biological Chemistry 280 (16), 16295-16304, 2005 | 225 | 2005 |
Redox regulation of surface protein thiols: identification of integrin α-4 as a molecular target by using redox proteomics T Laragione, V Bonetto, F Casoni, T Massignan, G Bianchi, E Gianazza, ... Proceedings of the National Academy of Sciences 100 (25), 14737-14741, 2003 | 166 | 2003 |
Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis M Basso, G Samengo, G Nardo, T Massignan, G D'Alessandro, S Tartari, ... PloS one 4 (12), e8130, 2009 | 135 | 2009 |
Insoluble mutant SOD1 is partly oligoubiquitinated in amyotrophic lateral sclerosis mice M Basso, T Massignan, G Samengo, C Cheroni, S De Biasi, M Salmona, ... Journal of Biological Chemistry 281 (44), 33325-33335, 2006 | 116 | 2006 |
Structural properties of Gerstmann-Sträussler-Scheinker disease amyloid protein M Salmona, M Morbin, T Massignan, L Colombo, G Mazzoleni, ... Journal of Biological Chemistry 278 (48), 48146-48153, 2003 | 94 | 2003 |
The N-terminal, polybasic region of PrPC dictates the efficiency of prion propagation by binding to PrPSc JA Turnbaugh, U Unterberger, P Saá, T Massignan, BR Fluharty, ... Journal of Neuroscience 32 (26), 8817-8830, 2012 | 89 | 2012 |
Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse T Massignan, F Casoni, M Basso, P Stefanazzi, E Biasini, M Tortarolo, ... Biochemical and biophysical research communications 353 (3), 719-725, 2007 | 84 | 2007 |
An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity IH Solomon, N Khatri, E Biasini, T Massignan, JE Huettner, DA Harris Journal of Biological Chemistry 286 (16), 14724-14736, 2011 | 80 | 2011 |
The neurotoxicity of prion protein (PrP) peptide 106–126 is independent of the expression level of PrP and is not mediated by abnormal PrP species L Fioriti, E Quaglio, T Massignan, L Colombo, RS Stewart, M Salmona, ... Molecular and Cellular Neuroscience 28 (1), 165-176, 2005 | 78 | 2005 |
Redox regulation of cyclophilin A by glutathionylation P Ghezzi, S Casagrande, T Massignan, M Basso, E Bellacchio, L Mollica, ... Proteomics 6 (3), 817-825, 2006 | 58 | 2006 |
A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity E Biasini, U Unterberger, IH Solomon, T Massignan, A Senatore, H Bian, ... Journal of Neuroscience 33 (6), 2408-2418, 2013 | 52 | 2013 |
Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor α (GDI)/Rab11 pathway T Massignan, E Biasini, E Lauranzano, P Veglianese, M Pignataro, ... Molecular & Cellular Proteomics 9 (4), 611-622, 2010 | 47 | 2010 |
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein T Massignan, S Cimini, C Stincardini, M Cerovic, I Vanni, SR Elezgarai, ... Scientific reports 6 (1), 23180, 2016 | 46 | 2016 |
A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein T Massignan, RS Stewart, E Biasini, IH Solomon, V Bonetto, R Chiesa, ... Journal of Biological Chemistry 285 (10), 7752-7765, 2010 | 45 | 2010 |
Synthetic miniprion PrP106 V Bonetto, T Massignan, R Chiesa, M Morbin, G Mazzoleni, L Diomede, ... Journal of Biological Chemistry 277 (35), 31327-31334, 2002 | 45 | 2002 |
Pharmacological inactivation of the prion protein by targeting a folding intermediate G Spagnolli, T Massignan, A Astolfi, S Biggi, M Rigoli, P Brunelli, ... Communications Biology 4 (1), 62, 2021 | 44 | 2021 |
Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes E Lauranzano, S Pozzi, L Pasetto, R Stucchi, T Massignan, K Paolella, ... Brain 138 (4), 974-991, 2015 | 41 | 2015 |
Regulation of redox-sensitive exofacial protein thiols in CHO cells T Laragione, E Gianazza, R Tonelli, P Bigini, T Mennini, F Casoni, ... Walter de Gruyter 387 (10_11), 1371-1376, 2006 | 36 | 2006 |
The hydrophobic core region governs mutant prion protein aggregation and intracellular retention E Biasini, L Tapella, E Restelli, M Pozzoli, T Massignan, R Chiesa Biochemical Journal 430 (3), 477-486, 2010 | 26 | 2010 |