| Gene ontology: tool for the unification of biology M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, ... Nature genetics 25 (1), 25-29, 2000 | 45503 | 2000 |
| Molecular portraits of human breast tumours CM Perou, T Sørlie, MB Eisen, M Van De Rijn, SS Jeffrey, CA Rees, ... nature 406 (6797), 747-752, 2000 | 21682 | 2000 |
| Cluster analysis and display of genome-wide expression patterns MB Eisen, PT Spellman, PO Brown, D Botstein Proceedings of the National Academy of Sciences 95 (25), 14863-14868, 1998 | 20670 | 1998 |
| Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications T Sørlie, CM Perou, R Tibshirani, T Aas, S Geisler, H Johnsen, T Hastie, ... Proceedings of the National Academy of Sciences 98 (19), 10869-10874, 2001 | 17562* | 2001 |
| Construction of a genetic linkage map in man using restriction fragment length polymorphisms. D Botstein, RL White, M Skolnick, RW Davis American journal of human genetics 32 (3), 314, 1980 | 15194 | 1980 |
| Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling AA Alizadeh, MB Eisen, RE Davis, C Ma, IS Lossos, A Rosenwald, ... Nature 403 (6769), 503-511, 2000 | 12695 | 2000 |
| Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. ES Lander, D Botstein Genetics 121 (1), 185-199, 1989 | 7126 | 1989 |
| Comprehensive Identification of Cell Cycle–regulated Genes of the Yeast Saccharomyces cerevisiae by Microarray Hybridization PT Spellman, G Sherlock, MQ Zhang, VR Iyer, K Anders, MB Eisen, ... Molecular biology of the cell 9 (12), 3273-3297, 1998 | 6539 | 1998 |
| Genomic expression programs in the response of yeast cells to environmental changes AP Gasch, PT Spellman, CM Kao, O Carmel-Harel, MB Eisen, G Storz, ... Molecular biology of the cell 11 (12), 4241-4257, 2000 | 5925 | 2000 |
| The Gene Ontology (GO) database and informatics resource Gene Ontology Consortium Nucleic acids research 32 (suppl_1), D258-D261, 2004 | 5653* | 2004 |
| Missing value estimation methods for DNA microarrays O Troyanskaya, M Cantor, G Sherlock, P Brown, T Hastie, R Tibshirani, ... Bioinformatics 17 (6), 520-525, 2001 | 4856 | 2001 |
| Exploring the new world of the genome with DNA microarrays PO Brown, D Botstein Nature genetics 21 (1), 33-37, 1999 | 3547 | 1999 |
| Advanced bacterial genetics: a manual for genetic engineering RW Davis, D Botstein, JR Roth Cold Spring Harbor Laboratory, 1980 | 3078 | 1980 |
| Systematic variation in gene expression patterns in human cancer cell lines DT Ross, U Scherf, MB Eisen, CM Perou, C Rees, P Spellman, V Iyer, ... Nature genetics 24 (3), 227-235, 2000 | 2755 | 2000 |
| Singular value decomposition for genome-wide expression data processing and modeling O Alter, PO Brown, D Botstein Proceedings of the National Academy of Sciences 97 (18), 10101-10106, 2000 | 2657 | 2000 |
| The transcriptional program in the response of human fibroblasts to serum VR Iyer, MB Eisen, DT Ross, G Schuler, T Moore, JCF Lee, JM Trent, ... science 283 (5398), 83-87, 1999 | 2645 | 1999 |
| The transcriptional program of sporulation in budding yeast S Chu, J DeRisi, M Eisen, J Mulholland, D Botstein, PO Brown, ... Science 282 (5389), 699-705, 1998 | 2452 | 1998 |
| GO:: TermFinder—open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes EI Boyle, S Weng, J Gollub, H Jin, D Botstein, JM Cherry, G Sherlock Bioinformatics 20 (18), 3710-3715, 2004 | 2314 | 2004 |
| Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data E Segal, M Shapira, A Regev, D Pe'er, D Botstein, D Koller, N Friedman Nature genetics 34 (2), 166-176, 2003 | 2215 | 2003 |
| Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease D Botstein, N Risch Nature genetics 33 (3), 228-237, 2003 | 2127 | 2003 |
