| An atlas of genetic influences on human blood metabolites SY Shin, EB Fauman, AK Petersen, J Krumsiek, R Santos, J Huang, ... Nature genetics 46 (6), 543-550, 2014 | 1426 | 2014 |
| Pharmacology and mechanism of action of pregabalin: the calcium channel α2–δ (alpha2–delta) subunit as a target for antiepileptic drug discovery CP Taylor, T Angelotti, E Fauman Epilepsy research 73 (2), 137-150, 2007 | 693 | 2007 |
| Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 Å and the complex with tungstate JA Stuckey, HL Schubert, EB Fauman, ZY Zhang, JE Dixon, MA Saper Nature 370 (6490), 571-575, 1994 | 522 | 1994 |
| Structure and function of the protein tyrosine phosphatases EB Fauman, MA Saper Trends in biochemical sciences 21 (11), 413-417, 1996 | 467 | 1996 |
| Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach C Menni, E Fauman, I Erte, JRB Perry, G Kastenmüller, SY Shin, ... Diabetes 62 (12), 4270-4276, 2013 | 464 | 2013 |
| Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals L Folkersen, S Gustafsson, Q Wang, DH Hansen, ÅK Hedman, A Schork, ... Nature metabolism 2 (10), 1135-1148, 2020 | 462 | 2020 |
| Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A EB Fauman, JP Cogswell, B Lovejoy, WJ Rocque, W Holmes, ... Cell 93 (4), 617-625, 1998 | 389 | 1998 |
| Plasma proteomic associations with genetics and health in the UK Biobank BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ... Nature 622 (7982), 329-338, 2023 | 351 | 2023 |
| An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci E Mountjoy, EM Schmidt, M Carmona, J Schwartzentruber, G Peat, ... Nature genetics 53 (11), 1527-1533, 2021 | 351 | 2021 |
| Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate WR Montfort, KM Perry, EB Fauman, JS Finer-Moore, GF Maley, L Hardy, ... Biochemistry 29 (30), 6964-6977, 1990 | 326 | 1990 |
| Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms JMM Howson, W Zhao, DR Barnes, WK Ho, R Young, DS Paul, LL Waite, ... Nature genetics 49 (7), 1113-1119, 2017 | 313 | 2017 |
| RNA methylation under heat shock control H Bügl, EB Fauman, BL Staker, F Zheng, SR Kushner, MA Saper, ... Molecular cell 6 (2), 349-360, 2000 | 303 | 2000 |
| Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease L Folkersen, E Fauman, M Sabater-Lleal, RJ Strawbridge, M Frånberg, ... PLoS genetics 13 (4), e1006706, 2017 | 285 | 2017 |
| The Cys (X) 5Arg catalytic motif in phosphoester hydrolysis ZY Zhang, Y Wang, L Wu, EB Fauman, JA Stuckey, HL Schubert, ... Biochemistry 33 (51), 15266-15270, 1994 | 232 | 1994 |
| Structure-based druggability assessment—identifying suitable targets for small molecule therapeutics EB Fauman, BK Rai, ES Huang Current opinion in chemical biology 15 (4), 463-468, 2011 | 204 | 2011 |
| S-adenosylmethionine-dependent methyltransferases: structures and functions X Cheng, R Blumenthal World Scientific, 1999 | 204 | 1999 |
| Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthases KM Perry, EB Fauman, JS Finer‐Moore, WR Montfort, GF Maley, F Maley, ... Proteins: Structure, Function, and Bioinformatics 8 (4), 315-333, 1990 | 203 | 1990 |
| A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes NR Van Zuydam, E Ahlqvist, N Sandholm, H Deshmukh, NW Rayner, ... Diabetes 67 (7), 1414-1427, 2018 | 169 | 2018 |
| Structure of a non-peptide inhibitor complexed with HIV-1 protease. Developing a cycle of structure-based drug design E Rutenber, EB Fauman, RJ Keenan, S Fong, PS Furth, ... Journal of Biological Chemistry 268 (21), 15343-15346, 1993 | 168 | 1993 |
| Structure and evolution of AdoMet-dependent methyltransferases EB FAUMAN, RM BLUMENTHAL, X CHENG S-Adenosylmethionine-dependent methyltransferases: structures and functions …, 1999 | 161 | 1999 |
Mark A Saper, Ph.D.Dept of Biological Chemistry, University of MichiganEmail verificata su umich.edu