| PI 3-kinase p110β: a new target for antithrombotic therapy SP Jackson, SM Schoenwaelder, I Goncalves, WS Nesbitt, CL Yap, ... Nature medicine 11 (5), 507-514, 2005 | 738 | 2005 |
| Inhibition of phosphoinositide 3-kinase β SP Jackson, AD Robertson, V Kenche, P Thompson, H Prabaharan, ... US Patent 7,598,377, 2009 | 88 | 2009 |
| Structural determinants defining the allosteric inhibition of an essential antibiotic target TPS da Costa, S Desbois, C Dogovski, MA Gorman, NE Ketaren, ... Structure 24 (8), 1282-1291, 2016 | 43 | 2016 |
| PDE2 inhibition by the PI3 kinase inhibitor LY294002 and analogues BM Abbott, PE Thompson Bioorganic & medicinal chemistry letters 14 (11), 2847-2851, 2004 | 34 | 2004 |
| A total synthesis of a highly N-methylated cyclodepsipeptide [2S,3S-Hmp]-aureobasidin L using solid-phase methods R Maharani, RTC Brownlee, AB Hughes, BM Abbott Tetrahedron 70 (14), 2351-2358, 2014 | 30 | 2014 |
| The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors LF Duncan, G Wang, OV Ilyichova, MJ Scanlon, B Heras, BM Abbott Molecules 24 (20), 3756, 2019 | 28 | 2019 |
| A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4 PR Gilson, R Kumarasingha, J Thompson, X Zhang, JS Penington, ... Scientific Reports 9 (1), 10292, 2019 | 28 | 2019 |
| Quaternary structure analyses of an essential oligomeric enzyme TPS da Costa, JB Christensen, S Desbois, SE Gordon, R Gupta, ... Methods in Enzymology 562, 205-223, 2015 | 28 | 2015 |
| A novel small molecule inhibitor of human Drp1 AA Rosdah, BM Abbott, CG Langendorf, Y Deng, JQ Truong, ... Scientific reports 12 (1), 21531, 2022 | 26 | 2022 |
| Synthesis and biological evaluation of substituted 3-anilino-quinolin-2 (1H)-ones as PDK1 inhibitors NJ O’Brien, M Brzozowski, DJD Wilson, LW Deady, BM Abbott Bioorganic & Medicinal Chemistry 22 (14), 3781-3790, 2014 | 25 | 2014 |
| Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants TPS da Costa, CJ Hall, S Panjikar, JA Wyllie, RM Christoff, S Bayat, ... Elife 10, e69444, 2021 | 24 | 2021 |
| Recent progress towards an effective treatment of amyotrophic lateral sclerosis using the SOD1 mouse model in a preclinical setting EC Browne, BM Abbott European journal of medicinal chemistry 121, 918-925, 2016 | 23 | 2016 |
| Synthetic studies of the phosphatidylinositol 3-kinase inhibitor LY294002 and related analogues B Abbott, P Thompson Australian journal of chemistry 56 (11), 1099-1106, 2003 | 23 | 2003 |
| Molecular evolution of an oligomeric biocatalyst functioning in lysine biosynthesis TP Soares da Costa, BM Abbott, AR Gendall, S Panjikar, MA Perugini Biophysical Reviews 10, 153-162, 2018 | 22 | 2018 |
| Synthesis of novel 1, 2, 5-oxadiazoles and evaluation of action against Acinetobacter baumannii RM Christoff, GL Murray, XP Kostoulias, AY Peleg, BM Abbott Bioorganic & Medicinal Chemistry 25 (24), 6267-6272, 2017 | 20 | 2017 |
| Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation MJ Buskes, KL Harvey, BJ Richards, R Kalhor, RM Christoff, CK Gardhi, ... Organic & biomolecular chemistry 14 (20), 4617-4639, 2016 | 18 | 2016 |
| Synthesis and biological evaluation of 2-anilino-4-substituted-7H-pyrrolopyrimidines as PDK1 inhibitors NJ O’Brien, M Brzozowski, MJ Buskes, LW Deady, BM Abbott Bioorganic & medicinal chemistry 22 (15), 3879-3886, 2014 | 17 | 2014 |
| Potent inhibitors of phosphatidylinositol 3 (PI3) kinase that have antiproliferative activity only when delivered as prodrug forms NJ O'Brien, S Amran, J Medan, B Cleary, LW Deady, IG Jennings, ... ChemMedChem 8 (6), 914-918, 2013 | 16 | 2013 |
| Pursuing DHDPS: an enzyme of unrealised potential as a novel antibacterial target RM Christoff, CK Gardhi, TPS da Costa, MA Perugini, BM Abbott MedChemComm 10 (9), 1581-1588, 2019 | 15 | 2019 |
| Inhibition of phosphoinositide 3-kinase beta SP Jackson, AD Robertson, V Kenche, P Thompson, H Prabaharan, ... PCT Int Appl. WO2004016607, 2004 | 13 | 2004 |
