Segui
Graham Robert Bignell
Graham Robert Bignell
Senior Staff Scientist, Wellcome Trust Sanger Institute
Email verificata su sanger.ac.uk
Titolo
Citata da
Citata da
Anno
Mutations of the BRAF gene in human cancer
H Davies, GR Bignell, C Cox, P Stephens, S Edkins, S Clegg, J Teague, ...
Nature 417 (6892), 949-954, 2002
129992002
Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
nature 500 (7463), 415-421, 2013
103382013
Identification of the breast cancer susceptibility gene BRCA2
R Wooster, G Bignell, J Lancaster, S Swift, S Seal, J Mangion, N Collins, ...
Nature 378 (6559), 789-792, 1995
49511995
Patterns of somatic mutation in human cancer genomes
C Greenman, P Stephens, R Smith, GL Dalgliesh, C Hunter, G Bignell, ...
Nature 446 (7132), 153-158, 2007
38112007
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ...
cell 144 (1), 27-40, 2011
26782011
Systematic identification of genomic markers of drug sensitivity in cancer cells
MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ...
Nature 483 (7391), 570-575, 2012
26402012
Mutational processes molding the genomes of 21 breast cancers
S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ...
Cell 149 (5), 979-993, 2012
21412012
A serine/threonine kinase gene defective in Peutz–Jeghers syndrome
A Hemminki, D Markie, I Tomlinson, E Avizienyte, S Roth, A Loukola, ...
Nature 391 (6663), 184-187, 1998
21151998
A comprehensive catalogue of somatic mutations from a human cancer genome
ED Pleasance, RK Cheetham, PJ Stephens, DJ McBride, SJ Humphray, ...
Nature 463 (7278), 191-196, 2010
20582010
The landscape of cancer genes and mutational processes in breast cancer
PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ...
Nature 486 (7403), 400-404, 2012
19462012
A landscape of pharmacogenomic interactions in cancer
F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...
Cell 166 (3), 740-754, 2016
18832016
The life history of 21 breast cancers
S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ...
Cell 149 (5), 994-1007, 2012
16092012
BRAF and RAS mutations in human lung cancer and melanoma
MS Brose, P Volpe, M Feldman, M Kumar, I Rishi, R Gerrero, E Einhorn, ...
Cancer research 62 (23), 6997, 2002
15052002
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
I Varela, P Tarpey, K Raine, D Huang, CK Ong, P Stephens, H Davies, ...
Nature 469 (7331), 539-542, 2011
14292011
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
GL Dalgliesh, K Furge, C Greenman, L Chen, G Bignell, A Butler, ...
Nature 463 (7279), 360-363, 2010
13822010
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ...
Nature communications 5 (1), 2997, 2014
10112014
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
PJ Campbell, PJ Stephens, ED Pleasance, S O'Meara, H Li, T Santarius, ...
Nature genetics 40 (6), 722-729, 2008
9962008
Intragenic ERBB2 kinase mutations in tumours
P Stephens, C Hunter, G Bignell, S Edkins, H Davies, J Teague, ...
Nature 431 (7008), 525-526, 2004
9622004
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
G Van Haaften, GL Dalgliesh, H Davies, L Chen, G Bignell, C Greenman, ...
Nature genetics 41 (5), 521-523, 2009
9372009
Identification of the familial cylindromatosis tumour-suppressor gene
GR Bignell, W Warren, S Seal, M Takahashi, E Rapley, R Barfoot, ...
Nature genetics 25 (2), 160-165, 2000
8492000
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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