Accesso pubblico

Signatures of mutational processes in human cancer

LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...

nature 500 (7463), 415-421, 2013

Mandati: US National Institutes of Health, Wellcome Trust

Systematic identification of genomic markers of drug sensitivity in cancer cells

MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ...

Nature 483 (7391), 570-575, 2012

Mandati: US National Institutes of Health, Howard Hughes Medical Institute, Cancer …

[HTML] cell.com

Mutational processes molding the genomes of 21 breast cancers

S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ...

Cell 149 (5), 979-993, 2012

Mandati: US National Institutes of Health

The landscape of cancer genes and mutational processes in breast cancer

PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ...

Nature 486 (7403), 400-404, 2012

Mandati: US National Institutes of Health, Research Foundation (Flanders), National …

[PDF] cell.com

A landscape of pharmacogenomic interactions in cancer

F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...

Cell 166 (3), 740-754, 2016

Mandati: US National Institutes of Health, Netherlands Organisation for Scientific …

[PDF] cell.com

The life history of 21 breast cancers

S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ...

Cell 149 (5), 994-1007, 2012

Mandati: US National Institutes of Health, Research Foundation (Flanders)

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

I Varela, P Tarpey, K Raine, D Huang, CK Ong, P Stephens, H Davies, ...

Nature 469 (7331), 539-542, 2011

Mandati: Swiss National Science Foundation, US National Institutes of Health, Cancer …

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ...

Nature communications 5 (1), 2997, 2014

Mandati: US National Institutes of Health, Research Foundation (Flanders), Wellcome Trust

Signatures of mutation and selection in the cancer genome

GR Bignell, CD Greenman, H Davies, AP Butler, S Edkins, JM Andrews, ...

Nature 463 (7283), 893-898, 2010

Mandati: US National Institutes of Health

[HTML] cell.com

The advantages of targeted protein degradation over inhibition: an RTK case study

GM Burslem, BE Smith, AC Lai, S Jaime-Figueroa, DC McQuaid, ...

Cell chemical biology 25 (1), 67-77. e3, 2018

Mandati: US National Institutes of Health

Recurrent SETBP1 mutations in atypical chronic myeloid leukemia

R Piazza, S Valletta, N Winkelmann, S Redaelli, R Spinelli, A Pirola, ...

Nature genetics 45 (1), 18-24, 2013

Mandati: Fondazione Cariplo

[HTML] jci.org

Whole exome sequencing of adenoid cystic carcinoma

PJ Stephens, HR Davies, Y Mitani, P Van Loo, A Shlien, PS Tarpey, ...

The Journal of clinical investigation 123 (7), 2965-2968, 2013

Mandati: US National Institutes of Health, Research Foundation (Flanders), Wellcome Trust

[PDF] cshlp.org

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

GR Bignell, T Santarius, JCM Pole, AP Butler, J Perry, E Pleasance, ...

Genome research 17 (9), 1296-1303, 2007

Mandati: Cancer Research UK

[HTML] aacrjournals.org

Transcription factor activities enhance markers of drug sensitivity in cancer

L Garcia-Alonso, F Iorio, A Matchan, N Fonseca, P Jaaks, G Peat, ...

Cancer research 78 (3), 769-780, 2018

Mandati: Wellcome Trust

[HTML] oup.com

Single-cell paired-end genome sequencing reveals structural variation per cell cycle

T Voet, P Kumar, P Van Loo, SL Cooke, J Marshall, ML Lin, ...

Nucleic acids research 41 (12), 6119-6138, 2013

Mandati: Research Foundation (Flanders), Wellcome Trust

[PDF] cell.com

Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development

R Wiedemeyer, C Brennan, TP Heffernan, Y Xiao, J Mahoney, ...

Cancer cell 13 (4), 355-364, 2008

Mandati: US National Institutes of Health

[HTML] sciencedirect.com

Recurrent ETNK1 mutations in atypical chronic myeloid leukemia

CB Gambacorti-Passerini, C Donadoni, A Parmiani, A Pirola, S Redaelli, ...

Blood, The Journal of the American Society of Hematology 125 (3), 499-503, 2015

Mandati: Wellcome Trust, Fondazione Cariplo

[HTML] plos.org

Amplification and overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24. 22-q24. 23 in medulloblastoma

Y Lu, SL Ryan, DJ Elliott, GR Bignell, PA Futreal, DW Ellison, S Bailey, ...

PloS one 4 (7), e6159, 2009

Mandati: Cancer Research UK

Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening

G Picco, ED Chen, LG Alonso, FM Behan, E Gonçalves, G Bignell, ...

Nature communications 10 (1), 2198, 2019

Mandati: UK Medical Research Council