| Multiple high-throughput analyses monitor the response of E. coli to perturbations N Ishii, K Nakahigashi, T Baba, M Robert, T Soga, A Kanai, T Hirasawa, ... Science 316 (5824), 593-597, 2007 | 799 | 2007 |
| Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae K Yoshikawa, T Tanaka, C Furusawa, K Nagahisa, T Hirasawa, H Shimizu FEMS yeast research 9 (1), 32-44, 2009 | 292 | 2009 |
| Identification of target genes conferring ethanol stress tolerance to Saccharomyces cerevisiae based on DNA microarray data analysis T Hirasawa, K Yoshikawa, Y Nakakura, K Nagahisa, C Furusawa, ... Journal of biotechnology 131 (1), 34-44, 2007 | 268 | 2007 |
| Comprehensive phenotypic analysis of single‐gene deletion and overexpression strains of Saccharomyces cerevisiae K Yoshikawa, T Tanaka, Y Ida, C Furusawa, T Hirasawa, H Shimizu Yeast 28 (5), 349-361, 2011 | 165 | 2011 |
| Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress T Horinouchi, K Tamaoka, C Furusawa, N Ono, S Suzuki, T Hirasawa, ... BMC genomics 11, 1-11, 2010 | 161 | 2010 |
| Differential importance of trehalose accumulation in Saccharomyces cerevisiae in response to various environmental stresses SA Mahmud, T Hirasawa, H Shimizu Journal of Bioscience and Bioengineering 109 (3), 262-266, 2010 | 139 | 2010 |
| Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum Y Shinfuku, N Sorpitiporn, M Sono, C Furusawa, T Hirasawa, H Shimizu Microbial cell factories 8, 1-15, 2009 | 134 | 2009 |
| 13C‐metabolic flux analysis for batch culture of Escherichia coli and its pyk and pgi gene knockout mutants based on mass isotopomer distribution of intracellular … Y Toya, N Ishii, K Nakahigashi, T Hirasawa, T Soga, M Tomita, K Shimizu Biotechnology progress 26 (4), 975-992, 2010 | 132 | 2010 |
| Recent advances in amino acid production by microbial cells T Hirasawa, H Shimizu Current opinion in biotechnology 42, 133-146, 2016 | 129 | 2016 |
| Adaptation of Saccharomyces cerevisiae cells to high ethanol concentration and changes in fatty acid composition of membrane and cell size TN Dinh, K Nagahisa, T Hirasawa, C Furusawa, H Shimizu PLoS One 3 (7), e2623, 2008 | 125 | 2008 |
| Integrated Metabolic Flux and Omics Analysis of Synechocystis sp. PCC 6803 under Mixotrophic and Photoheterotrophic Conditions T Nakajima, S Kajihata, K Yoshikawa, F Matsuda, C Furusawa, ... Plant and Cell Physiology 55 (9), 1605-1612, 2014 | 105 | 2014 |
| Effect of trehalose accumulation on response to saline stress in Saccharomyces cerevisiae SA Mahmud, K Nagahisa, T Hirasawa, K Yoshikawa, K Ashitani, ... Yeast 26 (1), 17-30, 2009 | 92 | 2009 |
| Reconstruction and verification of a genome-scale metabolic model for Synechocystis sp. PCC6803 K Yoshikawa, Y Kojima, T Nakajima, C Furusawa, T Hirasawa, H Shimizu Applied microbiology and biotechnology 92, 347-358, 2011 | 89 | 2011 |
| Comparative analysis of transcriptional responses to saline stress in the laboratory and brewing strains of Saccharomyces cerevisiae with DNA microarray T Hirasawa, Y Nakakura, K Yoshikawa, K Ashitani, K Nagahisa, ... Applied Microbiology and Biotechnology 70, 346-357, 2006 | 87 | 2006 |
| Direct measurement of isotopomer of intracellular metabolites using capillary electrophoresis time-of-flight mass spectrometry for efficient metabolic flux analysis Y Toya, N Ishii, T Hirasawa, M Naba, K Hirai, K Sugawara, S Igarashi, ... Journal of chromatography A 1159 (1-2), 134-141, 2007 | 85 | 2007 |
| Distinct roles of two anaplerotic pathways in glutamate production induced by biotin limitation in Corynebacterium glutamicum H Sato, K Orishimo, T Shirai, T Hirasawa, K Nagahisa, H Shimizu, ... Journal of bioscience and bioengineering 106 (1), 51-58, 2008 | 79 | 2008 |
| Increased 3-hydroxypropionic acid production from glycerol, by modification of central metabolism in Escherichia coli K Tokuyama, S Ohno, K Yoshikawa, T Hirasawa, S Tanaka, C Furusawa, ... Microbial cell factories 13, 1-11, 2014 | 74 | 2014 |
| Metabolic engineering of Saccharomyces cerevisiae to improve succinic acid production based on metabolic profiling Y Ito, T Hirasawa, H Shimizu Bioscience, biotechnology, and biochemistry 78 (1), 151-159, 2014 | 74 | 2014 |
| Integrated transcriptomic and metabolomic analysis of the central metabolism of Synechocystis sp. PCC 6803 under different trophic conditions K Yoshikawa, T Hirasawa, K Ogawa, Y Hidaka, T Nakajima, C Furusawa, ... Biotechnology journal 8 (5), 571-580, 2013 | 74 | 2013 |
| Effect of odhA overexpression and odhA antisense RNA expression on Tween-40-triggered glutamate production by Corynebacterium glutamicum J Kim, T Hirasawa, Y Sato, K Nagahisa, C Furusawa, H Shimizu Applied microbiology and biotechnology 81, 1097-1106, 2009 | 74 | 2009 |
