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Mohsin Badat
Titolo
Citata da
Citata da
Anno
Gene therapy in a patient with sickle cell disease
JA Ribeil, S Hacein-Bey-Abina, E Payen, A Magnani, M Semeraro, ...
New England Journal of Medicine 376 (9), 848-855, 2017
7982017
Defining genome architecture at base-pair resolution
P Hua, M Badat, LLP Hanssen, LD Hentges, N Crump, DJ Downes, ...
Nature 595 (7865), 125-129, 2021
1422021
Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia
S Mettananda, CA Fisher, D Hay, M Badat, L Quek, K Clark, P Hublitz, ...
Nature communications 8 (1), 424, 2017
1092017
Editing an alpha-globin enhancer in primary human hematopoietic stem cells as a treatment for beta-thalassemia. Nat Commun 8 (1): 424
S Mettananda, CA Fisher, D Hay, M Badat, L Quek, K Clark, P Hublitz, ...
282017
Treatment of diffuse large B‐cell lymphoma with secondary central nervous system involvement: encouraging efficacy using CNS‐penetrating R‐IDARAM chemotherapy
P Maciocia, M Badat, S Cheesman, S D'Sa, R Joshi, J Lambert, ...
British journal of haematology 172 (4), 545-553, 2016
282016
Direct correction of haemoglobin E β-thalassaemia using base editors
M Badat, A Ejaz, P Hua, S Rice, W Zhang, LD Hentges, CA Fisher, ...
Nature Communications 14 (1), 2238, 2023
172023
Combination-therapy with concurrent deferoxamine and deferiprone is effective in treating resistant cardiac iron-loading in aceruloplasminaemia.
M Badat, B Kaya, P Telfer
British Journal of Haematology 171 (3), 2015
172015
A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression
M Badat, JOJ Davies, CA Fisher, DJ Downes, A Rose, AB Glenthøj, ...
Blood, The Journal of the American Society of Hematology 137 (4), 572-575, 2021
92021
Vaccine‐induced immune thrombocytopenia and thrombosis: The decline in anti‐platelet factor 4 antibodies is assay‐dependent.
S Platton, L Schönborn, S Charrot, M Badat, J Boot, V McDonald, ...
British Journal of Haematology 197 (4), 2022
82022
Expression of the human alpha-globin cluster in the absence of the major regulatory element MCS-R2
M Badat, JOJ Davies, EJ van Beers, C Harteveld, D Downes, DR Higgs
Blood 132, 3632, 2018
22018
The evolving genetic landscape of telomere biology disorder dyskeratosis congenita
H Tummala, AJ Walne, M Badat, M Patel, AM Walne, J Alnajar, CC Chow, ...
EMBO Molecular Medicine, 1-23, 2024
12024
Base Editing Repairs the HbE Mutation Restoring the Production of Normal Globin Chains in Severe HbE/β-Thalassemia Patient Hematopoietic Stem Cells and Erythroid Cells
M Badat, P Hua, S Mettananda, C Fisher, N Roy, S Rice, A Roy, DR Higgs, ...
Blood 138, 2935, 2021
12021
Scientific business abstracts of the 113th annual meeting of the Association of Physicians of Great Britain and Ireland
TM Cacciottolo, A Perikari, A van der Klaauw, E Henning, LKJ Stadler, ...
QJM: An International Journal of Medicine 112 (9), 724-729, 2019
12019
Beginnings: the molecular pathology of hemoglobin
D Higgs, M Badat
Molecular Hematology, 1-16, 2024
2024
Ancient genomic linkage couples metabolism with erythroid development
AE Preston, JN Frost, M Badat, M Teh, AE Armitage, R Norfo, ...
bioRxiv, 2023
2023
An Ancient Transcriptional Hub Couples Developmentally Regulated Gene Expression with Metabolism during Erythropoiesis
AE Preston, JN Frost, M Badat, AE Armitage, S Wideman, M Teh, R Norfo, ...
Blood 140 (Supplement 1), 4-5, 2022
2022
Editing of haemoglobin genes
J Davies, D Higgs, M Badat
US Patent App. 17/278,679, 2022
2022
P104: base editing repairs the HbE mutation restoring the production of normal globin chains in severe HbE/β-thalassemia patient hematopoietic stem and erythroid cells
M Badat, P Hua, S Mettananda, C Fisher, N Roy, S Rice, A Roy, D Higgs, ...
HemaSphere 6, 19-20, 2022
2022
Developing genome-editing strategies to ameliorate HbE/beta-thalassaemia
M Badat
University of Oxford, 2021
2021
Genome editing of haemopoietic stem cells for treatment of thalassaemia
M Badat, S Mettananda, P Hua, R Schwessinger, J Hughes, D Higgs, ...
Oxford University Press, 2019
2019
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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